Results 1 to 10 of about 1,219 (173)

An MSRE-Assisted Glycerol-Enhanced RPA-CRISPR/Cas12a Method for Methylation Detection [PDF]

Biosensors
Background: Nasopharyngeal carcinoma (NPC) is a malignant tumor with high prevalence in southern China. Aberrant DNA methylation, as a hallmark of cancer, is extensively present in NPC, the detection of which facilitates early diagnosis and prognostic ...
Yike Jiang, Lan Ma
exaly   +4 more sources

MSRE TRANSIENT BENCHMARKS USING SAM [PDF]

EPJ Web of Conferences, 2021
In recent years, there has been renewed interest in Molten Salter Reactors (MSRs) for their potential advantages compared to reactors that rely on solid fuel.
Fei T., Hua T., Feng B., Heidet F., Hu R.   +4 more
doaj   +2 more sources

Application of a modified MSRE-qPCR method for detecting circulating cell-free DNA methylation in cervical cancer [PDF]

Frontiers in Oncology
BackgroundThe methylation status of cell-free DNA (cfDNA) shows promise for the clinical detection of cervical cancer and its precursors; however, its measurement in liquid biopsies is hindered by low cfDNA yields and technically demanding protocols ...
Yaru Liu, Yaru Liu, Yaru Liu, Tuping He, Shang Chen, Shenglong Wang, Zhihao Luo, Haixi Liu, Haixi Liu, Quan Liu, Quan Liu, Dixian Luo, Dixian Luo, Dixian Luo   +13 more
doaj   +2 more sources

Long-term Outcomes of Bladder Exstrophy–Epispadias Complex: A Multicenter Study by Indian Association of Pediatric Surgeons

Journal of Indian Association of Pediatric Surgeons
Background: Bladder exstrophy–epispadias complex (BEEC) requires complex reconstruction, yet long-term comparative outcomes from low- and middle-income countries are limited.
Kirtikumar J. Rathod, Vikesh Agrawal, Ramesh Babu, Himanshu Acharya, Vinay Chandrashekhar, Sanjay Rao, Santosh B. Kurbet, Mahantesh V. Patil, Sandip Kumar Rahul, Rupesh Keshri, Pradnya S. Bendre, Shilpa Sharma, Narendra Babu, Shubhalaxmi Nayak, Sumitra Kumar Biswas   +14 more
doaj   +2 more sources

Respiratory Bacteria and Antimicrobial Resistance Genes Detected by Long-Read Metagenomic Sequencing Following Feedlot Arrival, Subsequent Treatment Risk and Phenotypic Resistance in Feedlot Calves [PDF]

Antibiotics
Background/Objectives: Long-read metagenomic sequencing can assign antimicrobial resistance genes (ARGs) to speciated bacterial reads. This study evaluated whether metagenomic data from respiratory bacteria derived from feedlot calves sampled in the ...
Jennifer N. Abi Younes, Lianne McLeod, Stacey R. Lacoste, Zhijian Chai, Emily K. Herman, E. Luke McCarthy, John R. Campbell, Sheryl P. Gow, Paul Stothard, Matthew G. Links, Simon J. G. Otto, Cheryl L. Waldner   +11 more
doaj   +2 more sources

Novel Recombinase Polymerase Amplification Assay Is Sensitive for Detection of Macrolide Resistance Genes Relevant to Bovine Respiratory Disease Management in Feedlot Calves [PDF]

Veterinary Sciences
Macrolides are crucial for the management and treatment of bovine respiratory disease (BRD). However, antimicrobial resistance (AMR) threatens the efficacy of these and other antimicrobials.
Tara Funk, Lianne McLeod, Cheyenne C. Conrad, Rahat Zaheer, Simon J. G. Otto, Cheryl L. Waldner, Tim A. McAllister   +6 more
doaj   +2 more sources

ZERO POWER CRITICALITY BENCHMARK EVALUATION OF THE MSRE IN WIMS [PDF]

EPJ Web of Conferences, 2021
This paper discusses work done to benchmark the deterministic code WIMS [1] against the Monte Carlo code Serpent [2] and experiment. Comparison is made against the Molten Salt Reactor Experiment at Oak Ridge National Laboratory as well as a Serpent model
Constable Charlie, Lindley Ben, Parks Geoff   +2 more
doaj   +2 more sources

Novel triple-target panels utilizing methylation-sensitive restriction enzyme-based quantitative PCR for detecting advanced cervical precancers and cancers among high-risk HPV-positive women [PDF]

Journal of Translational Medicine
Background Optimal triage option for high-risk HPV-positive (hrHPV) women remains uncertain. We aimed to utilize methylation-sensitive restriction enzyme-based quantitative PCR (MSRE-qPCR) technique and develop triple-target human gene methylation panels
Shimin Chen, Hongshuang Dai, Shangying Hu, Tangjie Gao, Ming Chen, Xinghua Zhou, Lizhong Dai, Xuelian Zhao, Fanghui Zhao   +8 more
doaj   +2 more sources

MSRE-PCR for analysis of gene-specific DNA methylation [PDF]

Nucleic Acids Research, 2005
Abnormal DNA methylation is observed in certain promoters of neoplastic cells, although the likelihood of methylation for each individual promoter varies. Simultaneous analysis of many promoters in the same sample can allow use of statistical methods for identification of neoplasia.
Anait S Levenson, VÍCTOR V Levenson, Gartenhaus Ronald B   +2 more
exaly   +3 more sources

Preliminary Study of Transient Simulations in the MSRE Primary Loop with Modelica/TRANSFORM

Energies
Compared to conventional solid-fueled reactors, the liquid fuel transport in molten salt reactors (MSRs) leads to a strong coupling between thermal-hydraulics and neutronics.
Rui Yan, Yang Zou
exaly   +3 more sources