Results 61 to 70 of about 38,443 (210)

Extracellular matrix and proteolysis: mechanisms driving irreversible changes and shaping cell behavior

open access: yesThe FEBS Journal, EarlyView.
Irreversible ECM proteolysis by remodeling enzymes shapes development, homeostasis, and disease. ECM‐degrading proteases display cell specificity and are governed by shared mechanisms, exhibiting functional redundancy in generating matrikines, growth factors, and cytokines.
Inna Solomonov, Orit Kollet, Irit Sagi
wiley   +1 more source

Mass reconstruction with $M_2$ under constraint in semi-invisible production at a hadron collider

open access: yes, 2016
The mass-constraining variable $M_2$, a $(1+3)$-dimensional natural successor of extremely popular $M_{T2}$, possesses an array of rich features having the ability to use on-shell mass constraints in semi-invisible production at a hadron collider.
Konar, Partha, Swain, Abhaya Kumar
core   +1 more source

On-shell constrained $M_2$ variables with applications to mass measurements and topology disambiguation [PDF]

open access: yes, 2014
We consider a class of on-shell constrained mass variables that are 3+1 dimensional generalizations of the Cambridge $M_{T2}$ variable and that automatically incorporate various assumptions about the underlying event topology.
Cho, Won Sang   +6 more
core   +1 more source

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

open access: yesThe FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou   +4 more
wiley   +1 more source

Safety of intraocular anti-VEGF antibody treatment under in vitro HTLV-1 infection

open access: yesFrontiers in Immunology, 2023
IntroductionHTLV-1 (human T-cell lymphotropic virus type 1) is a retrovirus that infects approximately 20 million people worldwide. Many diseases are caused by this virus, including HTLV-1–associated myelopathy, adult T-cell leukemia, and HTLV-1 uveitis.
Yuan Zong   +5 more
doaj   +1 more source

Reconstructing the heavy resonance at hadron colliders

open access: yes, 2011
We investigate the method for constructing the invariant mass using the M_T2-assisted on-shell (MAOS) approximation to the invisible particle momenta in the cascade decays of a new particle resonance produced at hadron colliders.
Park, Chan Beom
core   +1 more source

Membrane‐type I metalloproteinase (MT1‐MMP): A key modifier of extracellular matrix microenvironment

open access: yesThe FEBS Journal, EarlyView.
MT1‐MMP: A cellular microenvironment modifier. MT1‐MMP is a major cellular microenvironment modifier, maintaining collagen homeostasis by degrading excess collagen (A), creating a migration path in motile cells such as cancer cells (B), modulating local microenvironmental signaling by cleaving transmembrane receptors (C), and destroying tissue ...
Yoshifumi Itoh, Masaki Inada
wiley   +1 more source

The Role of the Melatoninergic System in Circadian and Seasonal Rhythms—Insights From Different Mouse Strains

open access: yesFrontiers in Physiology, 2022
The melatoninergic system comprises the neurohormone melatonin and its molecular targets. The major source of melatonin is the pineal organ where melatonin is rhythmically produced during darkness.
Martina Pfeffer   +3 more
doaj   +1 more source

Resilient IT: Winning With People and Process

open access: yesInformation Systems Journal, EarlyView.
ABSTRACT In today's dynamic environment, IT organisations face numerous challenges from disruptions such as natural disasters, cybersecurity threats, international conflicts, evolving regulations, pandemics and recent global incidents such as the CrowdStrike outage.
Wesam Helou   +2 more
wiley   +1 more source

Characterization of the Mel1c melatoninergic receptor in platypus (Ornithorhynchus anatinus). [PDF]

open access: yesPLoS ONE, 2018
Melatonin is a neurohormone produced in both animals and plants. It binds at least three G-protein-coupled receptors: MT1 and MT2, and Mel1cGPR. Mammalian GPR50 evolved from the reptilian/avian Mel1c and lost its capacity to bind melatonin in all the ...
Célia Gautier   +8 more
doaj   +1 more source

Home - About - Disclaimer - Privacy