Results 111 to 120 of about 123,318 (262)
Knowledge and Management of Aquatic Ecosystems, 1996 Mitochondrial DNA (mtDNA) variation in the white-clawed crayfish, Austropotamobius pallipes pallipes, was examined by restriction endonuclease analysis of samples obtained from three geographical locations representing two very différent habitats : the ...
GRANDJEAN F., SOUTY-GROSSET C.
doaj +1 more source
European Journal of Entomology, 2010 This is the first study of the morphological and molecular variation in two peripheral populations of the butterfly Jutta Arctic, Oeneis jutta, a glacial relict species endangered by the fragmentation of its habitat in Poland.
Lech KRZYSZTOFIAK +5 more
doaj +1 more source
, 2003 MtDNA-based identification of blowflies in forensic entomology: More accurate postmortem interval estimation and ...
RI Dadour (14547584) +4 more
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Advanced Science, EarlyView.This study identifies Nupr1 as a crucial stress‐responsive orchestrator driving AD. Under severe stress, Nupr1 massively accumulates within mitochondria to sequester p53, triggering apoptosis and concurrently repressing the Gadd45b‐mediated survival program.
Xi Yang +14 more
wiley +1 more source
GENETICS, EVOLUTION, AND PHYLOGEOGRAPHY OF MOOSE [PDF]
Alces, 2004 Early studies of genetic variation in moose (Alces alces) indicated little variation. Recent studies have indicated higher levels of variation in nuclear markers; nonetheless, genetic heterogeneity of moose is relatively low compared with other mammals ...
Kris J. Hundertmark, R. Terry Bowyer
doaj
Mitochondrial Quality Control in Degenerative Musculoskeletal Diseases: Signaling Networks and Therapeutic Landscapes [PDF]
Advanced scienceMitochondrial quality control (MQC) collapse redefines osteoarthritis, intervertebral disc degeneration, and osteoporosis as disorders of organelle dysfunction. Damaged mitochondria leak mtDNA and metabolites, driving cGAS‐STING inflammation, epigenetic reprogramming, and metabolic memory.
Gao H +7 more
europepmc +2 more sources
Advanced Science, EarlyView.This review presents a pathology‐driven framework unifying nanomedicine across TBI, SCI, and PNI. Epidemiological evidence and comparative single‐cell transcriptomic reanalysis define shared pathological modules, injury‐specific effectors, and therapeutic bottlenecks. Six functional paradigms connect nanomaterial structure and biological fate to injury‐
Mouyuan Sun +12 more
wiley +1 more source
Biomarker Validation for Aging: Lessons from mtDNA Heteroplasmy Analyses in Early Cancer Detection
, 2009 The anticipated biological and clinical utility of biomarkers has attracted significant interest recently. Aging and early cancer detection represent areas active in the search for predictive and prognostic biomarkers.
Peter E. Barker, Mahadev Murthy
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Advanced Science, EarlyView.Oxaliplatin‐resistant colorectal cancer cells utilize a previously unappreciated PLK1‐CEP55‐ESCRT‐driven vesicular extrusion mechanism to clear L‐OHP‐induced cellular damage. The natural withanolide Tubocapsenolide A directly targets and inhibits PLK1 to disrupt this specific damage‐clearance machinery. This blockade induces severe nucleolar stress and
Yueying Yang +15 more
wiley +1 more source
Angewandte Chemie, EarlyView.This review highlights an emerging anticancer approach integrating platinum agents into photodynamic therapy (PDT) and photoactivated chemotherapy (PACT) systems, further augmented by cancer cell membrane‐ and organelle‐targeting. By directing photoactivated platinum complexes from nontargeted distribution to cancer cells or defined subcellular sites ...
Shu Chen +3 more
wiley +2 more sources