Results 91 to 100 of about 120,377 (263)

The initial peopling of the Americas: A growing number of founding mitochondrial genomes from Beringia [PDF]

, 2010
Pan-American mitochondrial DNA (mtDNA) haplogroup C1 has been recently subdivided into three branches, two of which (C1b and C1c) are characterized by ages and geographical distributions that are indicative of an early arrival from Beringia with Paleo ...
Perego, Ugo A., Baharak Hooshiar Kashani, Woodward, Scott R., Zimmermann B, Daniel Corach, Lancioni, Hovirag, Panara, Fausto, Huber G, Nora Babudri, Gabriela Huber, Kashani, Baharak Hooshiar, Babudri N, Valeria Carossa, Woodward SR, Anna Olivieri, Natalie M. Myres, Huber, Gabriela, Ekins JE, Jayne E. Ekins, Torroni, Antonio, Ugo A. Perego, Norman Angerhofer, Hooshiar Kashani, Baharak, Panara F, Scott R. Woodward, Parson W, Carossa, Valeria, Walther Parson, Gómez Carballa, Alberto, Pala, Maria, Babudri, Nora, Parson, Walther, Lancioni H, Myres NM, PEREGO, UGO ALESSANDRO, Alberto Gómez-Carballa, Antonio Torroni, Corach D, Zimmermann, Bettina, Ornella Semino, Salas A, Antonio Salas, Hovirag Lancioni, Angerhofer N, Gomez-Carballa, Alberto, Angerhofer, Norman, Achilli, Alessandro, Semino, Ornella, Salas, Antonio, Gómez Carballa A, Myres, Natalie M., Ekins, Jayne E., Corach, Daniel, Maria Pala, Alessandro Achilli, Bettina Zimmermann, Olivieri, Anna, Fausto Panara   +57 more
core   +1 more source

Senkyunolide I Inhibits mtDNA‐cGAS‐STING Signaling in Macrophages via Targeting VDAC1 Oligomerization to Attenuate Ulcerative Colitis

Advanced Science, EarlyView.
In macrophages, senkyunolide I (SEI) directly targets the K12 residue of VDAC1 to inhibit its stress‐induced oligomerization, a critical upstream event that effectively prevents mitochondrial DNA release and subsequent cGAS‐STING pathway activation.
Zhiming Ye, Yihang Huang, Bohao Han, Lei Zhang, Can Yu, Yang Yang, Bing Liu, Yongping Jian, Zhixiang Xu, Cheng Zeng   +9 more
wiley   +1 more source

Analysis of pathogenic variants of the mtDNA MT-TS1 gene in patients with hearing loss in Buryatia

Якутский медицинский журнал
In this work we searched for pathogenic variants of the mtDNA MT-TS1 gene in patients with hearing impairments in Buryatia. One rare variant m.7445A>C was found in the MT-TS1 gene out of five investigated variants in one patient (1/165; 0.6%).
T. V. Borisova, A. M. Cherdonova, G. P. Romanov, A. V. Solovyov, V. G. Pshennikova, F. M. Teryutin, N. A. Barashkov, S. A. Fedorova   +7 more
doaj   +1 more source

Matrilineal Components and Genetic Relationship of Silkies from China and Japan

The Journal of Poultry Science, 2010
Silkie is a famous black-bone chicken breed with beautiful silky feather. The unique medical property of this chicken was recorded in Chinese traditional medicine dictionary about 700 years ago.
Bing Zhou, Shi-Yi Chen, Qing Zhu, Yong-Gang Yao, Yi-Ping Liu   +4 more
doaj   +1 more source

Chemical Bond‐Orchestrated Energy Depletion to Augment Lung Cancer Chemo‐Immunotherapy

Advanced Science, EarlyView.
This study grafted dichloroacetic acid (DCA) into perylenediimide (PDI) skeleton via ionic or covalent bond to create novel metabolic agent PDIC‐AC and PDIC‐NAC, explicitly elaborated the underlying energy metabolism and therapeutic mechanism, and developed a promising strategy for energy metabolism‐targeting chemo‐immunotherapy by chemical bond ...
Xuejie Zhao, Yuting Liu, Xiao Huang, Liwen Zhao, Chunli Li, Yongwei Huang   +5 more
wiley   +1 more source

Complete mitochondrial genome of Sporophila maximiliani (Ave, Passeriformes)

Mitochondrial DNA. Part B. Resources, 2017
Sporophila maximiliani, commonly known as Great-billed Seed-Finch or ‘bicudo’, is a trafficked bird in Brazil due to the species’ beauty and singing, which is appreciated by breeders and collectors.
Sandra Ludwig, Ana Paula Vimieiro Martins, Ana Luiza Lemos Queiroz, Anderson Oliveira do Carmo, Bárbara Bruna Ribeiro Oliveira-Mendes, Evanguedes Kalapothakis   +5 more
doaj   +1 more source

Analysis of mitochondrial DNA variation in the Egyptian population and its implications for forensic DNA analysis [PDF]

, 2010
The genetic sequence of human mitochondrial DNA (mtDNA) is of particular interest to forensic investigations involving human identification, as well as population genetics.
Gomaa, R
core  

IFI27 and BAX are Essential for GSDME‐Mediated Myeloma Cell Pyroptosis

Advanced Science, EarlyView.
The proposed model of GSDME‐mediated MM cell pyroptosis modulated by IFI27 and BAX. IFI27 is downregulated in MM cells. Upon pyroptotic stimulation, such as DOX or ETO treatment, IFI27 is induced, therefore liberating BAX from BCL‐2 ❶. BAX is then recruited to mitochondria and forms homo‐oligomeric channels in OMM, therefore leading to cytochrome C ...
Yaoli Cui, Yuening Sun, Ziyang Liu, Xuntao Lai, Yunshu Zhao, Yan'er Wang, Yuanming He, Fang Xu, Du Feng, Longlong Liu, Zhenqian Huang, Lijie Xing, Xinliang Mao   +12 more
wiley   +1 more source

The preliminary molecular study of four skink species in Rajaji Tiger Reserve (RTR), Uttarakhand, using 12S rRNA mitochondrial locus

Mitochondrial DNA. Part B. Resources, 2017
Skinks are present under the Scincidae family, widely distributed species in Indian subcontinent. Uttarakhand is one of the hotspot where number of identified and unidentified skink species reported.
Ankita Rajpoot, Archana Bahuguna, Ved Prakash Kumar, Dhyanendra Kumar   +3 more
doaj   +1 more source

Phylogenetic relatedness of Erebia medusa and E. epipsodea (Lepidoptera: Nymphalidae) confirmed

European Journal of Entomology, 2013
The extensive genus Erebia is divided into several groups of species according to phylogenetic relatedness. The species Erebia medusa was assigned to the medusa group and E. epipsodea to the alberganus group.
Martina ŠEMELÁKOVÁ, Peter PRISTAŠ, Ľubomír PANIGAJ   +2 more
doaj   +1 more source