Results 71 to 80 of about 123,318 (262)

Chemical Bond‐Orchestrated Energy Depletion to Augment Lung Cancer Chemo‐Immunotherapy

Advanced Science, EarlyView.
This study grafted dichloroacetic acid (DCA) into perylenediimide (PDI) skeleton via ionic or covalent bond to create novel metabolic agent PDIC‐AC and PDIC‐NAC, explicitly elaborated the underlying energy metabolism and therapeutic mechanism, and developed a promising strategy for energy metabolism‐targeting chemo‐immunotherapy by chemical bond ...
Xuejie Zhao, Yuting Liu, Xiao Huang, Liwen Zhao, Chunli Li, Yongwei Huang   +5 more
wiley   +1 more source

Complete mitochondrial genome of an undescribed gnomefish of the genus Scombrops (Teleostei, Scombropidae) from southern waters off Kyushu Island, Japan

Mitochondrial DNA. Part B. Resources, 2017
The complete mitochondrial genome of an undescribed gnomefish species of the genus Scombrops was determined using a PCR-based method. The total length of mitochondrial DNA (mtDNA) was 16,521 bp, and included 13 protein-coding genes, two ribosomal RNA ...
Yukako Mochizuki, Riko Yamada, Hirotoshi Shishido, Yasuji Masuda, Shizuko Nakai, Noriyuki Takai, Shiro Itoi, Haruo Sugita   +7 more
doaj   +1 more source

The complete mitochondrial genome sequence of the hawk moth, Theretra oldenlandiae (Lepidoptera: Sphingidae)

Mitochondrial DNA. Part B. Resources, 2020
In this study, we analyzed the complete mitochondrial genome sequence of the hawk moth, Theretra oldenlandiae. The complete mitogenome sequence of T. oldenlandiae was observed to be a circular molecule 15,312 bp long and consisting of 13 protein-coding ...
Xu Wang, Hao Zhang, Wei-Ying Qu, Yi-Xin Huang   +3 more
doaj   +1 more source

The Multifaceted Origin of Taurine Cattle Reflected by the Mitochondrial Genome [PDF]

, 2009
A Neolithic domestication of taurine cattle in the Fertile Crescent from local aurochsen (Bos primigenius) is generally accepted, but a genetic contribution from European aurochsen has been proposed.
Malusà, Arianna, Perego, Ugo A., Baharak Hooshiar Kashani, Baharak Hooshiar, Bandelt, Hans-Jürgen, Ferretti, Luca, Pala, Maria, Paolo Ajmone-Marsan, Silvia Bonfiglio, BANDELT HJ, Ugo A Perego, PEREGO, UGO ALESSANDRO, Hans-Jürgen Bandelt, Antonio Torroni, Ornella Semino, Ajmone-Marsan, Paolo, Ro Achilli, Achilli, Alessandro, Liotta, Luigi, Semino, Ornella, Anna Olivieri, LIOTTA L, Ajmone Marsan, Paolo, AJMONE MARSAN P, Luca Ferretti, Luigi Liotta, Torroni, Antonio, Maria Pala, Ugo A. Perego, Alessandro Achilli, Olivieri, Anna, Bonfiglio, Silvia, Arianna Malusà, Hooshiar Kashani, Baharak, MALUSA', ARIANNA, Bonfiglio S., Achilli Alessandro, Hooshiar Kashani B, Ajmone-Marsan Paolo, Pala M., Torroni Antonio, Kashani B. H., Bonfiglio S, Bandelt H. J., Liotta Luigi, Kashani Baharak Hooshiar, Ferretti L., Olivieri Anna, Malusà Arianna, Ajmone Marsan P., Perego UA, Semino O., Malusà A, Achilli A., Lotta L, Malusà A., Perego U. A., Bonfiglio Silvia, Bandelt Hans-Jürgen, Pala Maria, Ferretti Luca, Torroni A., Olivieri A, Semino Ornella, Semino O, Perego Ugo A., Olivieri A., Ferretti L, Pala M   +68 more
core   +2 more sources

IFI27 and BAX are Essential for GSDME‐Mediated Myeloma Cell Pyroptosis

Advanced Science, EarlyView.
The proposed model of GSDME‐mediated MM cell pyroptosis modulated by IFI27 and BAX. IFI27 is downregulated in MM cells. Upon pyroptotic stimulation, such as DOX or ETO treatment, IFI27 is induced, therefore liberating BAX from BCL‐2 ❶. BAX is then recruited to mitochondria and forms homo‐oligomeric channels in OMM, therefore leading to cytochrome C ...
Yaoli Cui, Yuening Sun, Ziyang Liu, Xuntao Lai, Yunshu Zhao, Yan'er Wang, Yuanming He, Fang Xu, Du Feng, Longlong Liu, Zhenqian Huang, Lijie Xing, Xinliang Mao   +12 more
wiley   +1 more source

Sequence and phylogenetic analysis of the mitochondrial genome for the Northern Anchovy, Engraulis mordax (Engraulidae: Clupeiformes)

Mitochondrial DNA. Part B. Resources, 2019
The northern anchovy, Engraulis mordax, is a small planktivorous fish from the northeastern Pacific Ocean that is an important forage for fishes, birds, and marine mammals, and is also the target of a commercial fishery.
Olivia H. Lewis, Sean C. Lema
doaj   +1 more source

Klotho‐Derived Peptide 1 Protects against Acute Kidney Injury by Directly Targeting Mitochondrial ATAD3A

Advanced Science, EarlyView.
This study uncovers that KP1, a Klotho‐derived peptide, protects the kidney against acute kidney injury, a clinical syndrome with high morbidity and mortality. KP1 enters tubular epithelial cells via endocytosis, directly interacts with the mitochondrial ATAD3A/HIGD2A complex, thereby preventing cytochrome c release, and caspases activation, and ...
Xiaoyao Zhang, Shihui Lin, Tianyu Wu, Zhixin Zhang, Hong Zhou, Xue Hong, Youhua Liu   +6 more
wiley   +1 more source

Complete mitochondrial genome of the four-lined snake, Elaphe quatuorlineata (Bonnaterre, 1790)

Mitochondrial DNA. Part B. Resources, 2019
Here, we present complete mitochondrial genome of the four-lined snake, Elaphe quatuorlineata (Bonnaterre, 1790) and its comparison with closely related E. sauromates (Pallas, 1814).
Daniel Jablonski, Katarina Soltys, Evgeniy Simonov   +2 more
doaj   +1 more source

An Unusual Amino Acid Substitution Within Hummingbird Cytochrome c Oxidase Alters a Key Proton-Conducting Channel

G3: Genes, Genomes, Genetics, 2020
Hummingbirds in flight exhibit the highest mass-specific metabolic rate of all vertebrates. The bioenergetic requirements associated with sustained hovering flight raise the possibility of unique amino acid substitutions that would enhance aerobic ...
Cory D. Dunn, Bala Anı Akpınar, Vivek Sharma   +2 more
doaj   +1 more source

A Note On The Denisova Cave mtDNA Sequence [PDF]

, 2010
The recently published Altai fossil sequence from Denisova Cave was purported to be so different from anatomically modern humans, yet have the physiological landmarks of that species designation. When the published sequence was examined it was found that
Niccolo Caldararo
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