Results 71 to 80 of about 7,772 (216)
Xenogeneic Mitochondrial Transplantation Improves Selected Age‐Associated Phenotypes in Mice
Advanced Science, EarlyView.Yak‐derived xenogeneic mitochondrial transplantation improves selected age‐associated phenotypes in mice, enhances mitochondrial functional readouts, and engages host mitochondrial quality‐control pathways. Broad tissue biodistribution, increased ATP production and mtDNA copy number, reduced ROS levels and dysfunctional mitochondria, improved motility ...
Wenpeng Li +5 more
wiley +1 more source
Matrilineal Components and Genetic Relationship of Silkies from China and Japan
The Journal of Poultry Science, 2010 Silkie is a famous black-bone chicken breed with beautiful silky feather. The unique medical property of this chicken was recorded in Chinese traditional medicine dictionary about 700 years ago.
Bing Zhou +4 more
doaj +1 more source
Advanced Science, EarlyView.ABSTRACT Doxorubicin‐induced cardiomyopathy (DIC) remains a dose‐limiting clinical challenge. This study reveals that cardiac vascular endothelial cells (CVECs) act as initial sensors of doxorubicin cardiotoxicity: circulating doxorubicin activates the cGAS‑STING pathway in CVECs, triggering NLRP3 inflammasome‑mediated pyroptosis and release of ...
Wang Jun +10 more
wiley +1 more source
Complete mitochondrial genome of Sporophila maximiliani (Ave, Passeriformes)
Mitochondrial DNA. Part B. Resources, 2017 Sporophila maximiliani, commonly known as Great-billed Seed-Finch or ‘bicudo’, is a trafficked bird in Brazil due to the species’ beauty and singing, which is appreciated by breeders and collectors.
Sandra Ludwig +5 more
doaj +1 more source
mtDNA synthesis ignites the inflammasome [PDF]
Nature Reviews Immunology, 2018 Macrophage priming by inflammatory stimuli drives the new synthesis and oxidation of mitochondrial DNA, which is essential for NLRP3 inflammasome activation.
openaire +2 more sources
Advanced Science, EarlyView.This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng +14 more
wiley +1 more source
Mitochondrial DNA. Part B. Resources, 2017 Skinks are present under the Scincidae family, widely distributed species in Indian subcontinent. Uttarakhand is one of the hotspot where number of identified and unidentified skink species reported.
Ankita Rajpoot +3 more
doaj +1 more source
Phylogenetic relatedness of Erebia medusa and E. epipsodea (Lepidoptera: Nymphalidae) confirmed
European Journal of Entomology, 2013 The extensive genus Erebia is divided into several groups of species according to phylogenetic relatedness. The species Erebia medusa was assigned to the medusa group and E. epipsodea to the alberganus group.
Martina ŠEMELÁKOVÁ +2 more
doaj +1 more source
Biomarkers of Sarcopenia: Current Status and Future Perspectives
AGING MEDICINE, EarlyView.In this review, we summarize the various biomarkers discovered in recent years, including biochemical, imaging, and physical testing markers. We analyze their advantages and disadvantages and propose potential ways to improve the diagnostic accuracy of biomarkers, as well as future research directions.
Bijin Luo +6 more
wiley +1 more source