Results 121 to 130 of about 166,442 (338)

The mtDNA of Human Rights [PDF]

Science, Technology, & Human Values, 2017
Mitochondrial replacement therapy is a process whereby a child is created by combining the nuclear DNA of two people wishing to have a child with mitochondrial DNA (mtDNA) donated by a third person. It poses a new question as to the extent of a person’s right to know the identity of those from whom their DNA is inherited. In commentary upon Turkmendag’
openaire   +2 more sources

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

Advanced Science, EarlyView.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li, Yumei Wang, Xiaoxi Fan, Miao Xu, Jiawen Li, Wenfei Tan, Jianxiang Zhang, Heran Li   +7 more
wiley   +1 more source

GENETICS, EVOLUTION, AND PHYLOGEOGRAPHY OF MOOSE [PDF]

Alces, 2004
Early studies of genetic variation in moose (Alces alces) indicated little variation. Recent studies have indicated higher levels of variation in nuclear markers; nonetheless, genetic heterogeneity of moose is relatively low compared with other mammals ...
Kris J. Hundertmark, R. Terry Bowyer
doaj  

Some limitations in the use of the mitochondrial DNA cytb gene as a molecular marker for phylogenetic and population genetic studies by the example of the Apodemus genus

Вавиловский журнал генетики и селекции, 2015
The interpretation of a signal sent by the mtDNA cytb gene as a molecular marker in phylogenetic and population genetic research can be complicated by cumulative influence of parallel mutations, i.e., the entropy of nucleotide sequences.
A. G. Lapinski, M. V. Pavlenko, L. L. Solovenchuk, V. V. Gorbachev   +3 more
doaj   +1 more source

Uncovering the sources of DNA found on the Turin Shroud [PDF]

, 2015
The Turin Shroud is traditionally considered to be the burial cloth in which the body of Jesus Christ was wrapped after his death approximately 2000 years ago.
Achilli, Alessandro, Barcaccia, Gianni, Galla, Giulio, Olivieri, Anna, Torroni, Antonio   +4 more
core   +1 more source

Prehistoric and historic traces in the mtDNA of Mozambique: insights into the Bantu expansions and the slave trade [PDF]

, 2001
Luı́sa Pereira, Vincent Macaulay, Antonio Torroni, Rosaria Scozzari, Maria João Prata, António Amorim   +5 more
openalex   +1 more source

Mitochondrial Transplantation as a Therapeutic Strategy for Inherited Mitochondrial Diseases

Advanced Science, EarlyView.
Mitochondrial transplantation (MTx) offers a promising therapeutic avenue for mitochondrial diseases. This review comprehensively evaluates MTx, differentiating its feasibility for mtDNA‐ and nDNA‐based disorders. It examines its potential for genetic correction, alongside inherent limitations, technical challenges, and crucial ethical considerations ...
Parmeshar Singh, Amir Tahavvori, Cyrus E. Kuschner, Blanca B. Espin, Jacob Kazmi, Sofhia V. Ramos, Tai Yin, Kei Hayashida, Kanako Ito‐Hagiwara, Yusuke Endo, Keitaro Yoshioka, Jun Hagiwara, Avijot Sohi, Alisha Oropallo, Ghania Haddad, Timmy Li, Lance B. Becker, Junhwan Kim   +17 more
wiley   +1 more source

European mtDNA Variants Are Associated With Differential Responses to Cisplatin, an Anticancer Drug: Implications for Drug Resistance and Side Effects. [PDF]

, 2019
Background: Cisplatin, a powerful antitumor agent, causes formation of DNA adducts, and activation of apoptotic pathways. Presently, cisplatin resistance develops in up to 70% of patients but the underlying molecular mechanism(s) are unclear and there ...
Abedi, Sina, Atilano, Shari R, Bota, Daniela, Chang, Steven, Chwa, Marilyn, Jazwinski, S Michal, Kenney, M Cristina, Liu, Catherine, Lu, Stephanie, Miceli, Michael V, Norman, Lucas, Patel, Tej H, Thaker, Kunal, Udar, Nitin   +13 more
core   +1 more source

Comparative Genetics Using Three mtDNA Markers in Aedes aegypti (Linnaeus) Populations from Municipalities in the State of Mato Grosso, Brazil.

, 2023
Sandra Mariotto, Mari Rose Oliveira Silva, Cristina Márcia de Menezes Butakka, Lenicy Lucas de Miranda Cerqueira, Rosina Djunko Miyazaki, Giovanna Campos Camolezi, Fabiana Aparecida Caldart Rodrigues   +6 more
openalex   +2 more sources

Hub genes and diagnostic model associated with mitochondrial function in Alzheimer's disease

Animal Models and Experimental Medicine, EarlyView.
Alzheimer's disease (AD) is the most common neurodegenerative disorder, and mitochondrial dysfunction has been confirmed in AD patients and mouse models. However, the pathogenic genes associated with AD and early diagnostic methods based on mitochondrial function remain to be explored.
Xuchao Zhu, Ling Zhang, Chuan Qin
wiley   +1 more source