Arthritis &Rheumatology, Accepted Article.Objective Mitochondria are organelles with a hypomethylated circular genome. Mitochondrial DNA (mtDNA) in the systemic circulation has been implicated in inflammation. This study investigates the role of circulating DNA in systemic sclerosis (SSc) and the cellular mechanisms governing its release.
Stavros Giaglis +9 more
wiley +1 more source
Quantification and sequencing of somatic deleted mtDNA in single cells: evidence for partially duplicated mtDNA in aged human tissues [PDF]
, 2001 Natalya D. Bodyak
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GENETIC POLYMORPHISM AND TAXONOMIC STATUS OF ROE DEER (ARTIODACTYLA, CERVIDAE, CAPREOLUS GRAY, 1821) OF THE PENZA REGION ACCORDING TO THE RESULTS OF mtDNA ANALYSIS [PDF]
, 2023 С. В. Титов +3 more
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Exosome as bioactive nanovesicle for diagnostic and therapeutic applications in periodontitis
BMEMat, EarlyView.This review introduces the mechanism that exosomes participate in the pathogenesis of periodontitis and their potential as biomarkers for early diagnosis and summarizes the application of cell‐ or plant‐derived exosomes or engineered exosomes in periodontitis or periodontal regeneration while proposing the perspective of translational application of ...
Yu Wang +6 more
wiley +1 more source
Probing the pathogenicity of patient-derived variants of MT-ATP6 in yeast
Disease Models & Mechanisms, 2023 Emilia Baranowska +8 more
doaj +1 more source
Relationships of scincid lizards (Mabuya spp.) from the islands of the Gulf of Guinea based on mtDNA sequence data [PDF]
, 2005 José Jesus +2 more
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Biomaterial design strategies for enhancing mitochondrial transplantation therapy
BMEMat, EarlyView.Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang +12 more
wiley +1 more source
The distinct spatiotemporal distribution and effect of feed restriction on mtDNA copy number in broilers [PDF]
, 2020 Xiangli Zhang +8 more
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Avoiding misleading estimates using mtDNA heteroplasmy statistics to study bottleneck size and selection [PDF]
, 2022 Konstantinos Giannakis +3 more
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Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy
BMEMat, EarlyView.This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma +9 more
wiley +1 more source