Low doses of ozone alleviate cardiomyocyte ferroptosis induced by hypoxia-reoxygenation injury via the AMPK-mTOR pathway. [PDF]
Ding Y, Hong T.
europepmc +1 more source
As a New Tumor Suppressor Gene, PID1 Activates the AMPK-mTOR Signal to Inhibit the Progression of Bladder Cancer. [PDF]
Sun L, Liu C, Cao Y, Li J, Yuan L.
europepmc +1 more source
Role of AMP-Activated Protein Kinase (AMPK) in Female Reproduction: A Review. [PDF]
Kamar Bashah NA+5 more
europepmc +1 more source
mTOR Modulates NLRP3 Inflammasome Activation via Nuclear Translocation and STAT1 Inhibition. [PDF]
González-Dominguez A+6 more
europepmc +1 more source
Circulating Levels of VEGF, mTOR and MAPK in Patients With Port-Wine Stains. [PDF]
Huang Y+5 more
europepmc +1 more source
Treinamento de força versus treinamento de endurance. Existe compatibilidade?
Bernardo Neme Ide+7 more
doaj
mTOR Pathway and mTOR Inhibitors in Cancer Therapy [PDF]
1. N. Kubica and J. Blenis "mTORC1: A signaling integration node involved in cell growth" 2. Z. Feng and A.J. Levine "The Regulation of the IGF-1/mTOR Pathway by the p53 Tumor Suppressor Gene Functions" 3. H. Mead, M. Zeremski and M. Guba "mTOR Signaling in Angiogenesis" 4. J. Brugaroles "mTOR signaling and hypoxia" 5. D. Akhavan and P.S. Mischel "mTOR
Vitaly A. Polunovsky, Peter J. Houghton
openaire +1 more source
Related searches:
mTOR Signaling Pathway and mTOR Inhibitors in Cancer Therapy
Hematology/Oncology Clinics of North America, 2012Mammalian target of rapamycin (mTOR) is a serine/threonine protein kinase. It is ubiquitously expressed in cells and is a therapeutic target for the cancer treatment arsenal. Despite the great responses obtained in tumors addicted to specific mutations or overactivation of key members of the mTOR pathway (HiF1α in RCC, cyclin D1 in MCL, or TSC in SEGA),
Alejandro Gomez-Pinillos+1 more
openaire +3 more sources
mTOR Pathway and mTOR Inhibitors as Agents for Cancer Therapy
Current Cancer Drug Targets, 2008Research into mTOR, mammalian Target Of Rapamycin as an important drug target continues to be extremely interesting, both in terms of the increased molecular knowledge being acquired at the basis of various human diseases, and also for possible applications in drug cancer therapy.
Renzo Lazzarini+5 more
openaire +3 more sources