Improved Formazan Dissolution for Bacterial MTT Assay [PDF]
The MTT assay, based on the enzymatic reduction of the water-soluble, yellowish tetrazolium salt 3-(4,5-dimethylthiazol)-2,5-diphenyl-tetrazolium bromide (MTT) to purple formazan, is commonly used for assessment of cell viability and proliferation ...
Ludmil Benov
doaj +6 more sources
Evaluation of Direct Colorimetric MTT Assay for Rapid Detection of Rifampicin and Isoniazid Resistance in Mycobacterium tuberculosis. [PDF]
With the spread of multidrug-resistant tuberculosis (MDR-TB) strains there is an increasing need for new accurate and cost-effective methods for a rapid diagnostic and drug susceptibility testing (DST), particularly in low-income countries where ...
Gadissa Bedada Hundie +2 more
doaj +11 more sources
Interference of Phenylethanoid Glycosides from Cistanche tubulosa with the MTT Assay [PDF]
The MTT assay, as a screening method, has been widely used to measure the viability and proliferation of cells. However, it should be noted that MTT assay may not accurately reflect the effect of Cistanche tubulosa ethanolic extract on EA.hy926 cells ...
Yu-Jie Wang +3 more
doaj +5 more sources
The MTT assay application to measure the viability of spermatozoa: a variety of the assay protocols [PDF]
The MTT reduction assay is one of the methods used to evaluate the viability of sperm. In the assay, a tetrazolium component (MTT) is converted into MTT formazan by some specific enzymes in the viable cells.
Kakanang Buranaamnuay
doaj +3 more sources
Quantitative evaluation of human sperm viability using MTT assay: A laboratory study [PDF]
Background: 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyl tetrazolium bromide (MTT) assay which evaluates cellular mitochondrial activity is widely used for the assessment of cell proliferation and viability.
Hamid Reza Momeni +2 more
doaj +3 more sources
Anti-cancer drug-mediated increase in mitochondrial mass limits the application of metabolic viability-based MTT assay in cytotoxicity screening. [PDF]
The high-throughput metabolic viability-based colorimetric MTT test is commonly employed to screen the cytotoxicity of different chemotherapeutic drugs.
Kumar A, Rai Y, Bhatt AN.
europepmc +4 more sources
DRAQ7 as an Alternative to MTT Assay for Measuring Viability of Glioma Cells Treated With Polyphenols. [PDF]
Background/Aim: The tetrazolium-based MTT cytotoxicity assay is well established for screening putative anti-cancer agents. However, it has limitations including lack of reproducibility with glioma cells treated with polyphenols.
Rooprai HK +6 more
europepmc +4 more sources
Mathematical Modeling for an MTT Assay in Fluorine-Containing Graphene Quantum Dots [PDF]
The paper reports on a new mathematical model, starting with the original Hill equation which is derived to describe cell viability (V) while testing nanomaterials (NMs).
Paulo C. Morais, Dieime C. Silva
doaj +2 more sources
Effect of growth media on the MTT colorimetric assay in bacteria.
Reduction of tetrazolium salts to colored formazan products by metabolically active cells is widely used for assessment of cell viability. Among the tetrazolium compounds most commonly used is MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium ...
Ludmil Benov
doaj +3 more sources
Anticancer metal complexes: synthesis and cytotoxicity evaluation by the MTT assay. [PDF]
Ganot N +4 more
europepmc +3 more sources

