Applied Sciences, 2021 Photodynamic therapy (PDT) combines light, a photosensitizing chemical substance, and molecular oxygen to elicit cell death and is employed in the treatment of a variety of diseases, including cancer.
Edith Alejandra Carreño +5 more
doaj +2 more sources
MTT assay to evaluate the cytotoxic potential of a drug
Bangladesh Journal of Pharmacology, 2017 Quantification of cell viability and proliferation form the fundamental for numerous in vitro assays in response to external factors. An MTT assay is a colorimetric assay based on assessing the cell metabolic activity.
Ashutosh Bahuguna +3 more
doaj +2 more sources
Evaluating the Proliferation of Human PeripheralBlood Mononuclear Cells Using MTT Assay [PDF]
International Journal of Basic Science in Medicine, 2017 Introduction: 3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) assay is a safe, convenient, and low-cost technique with high applications for the measurement of cell proliferation rate in researches and clinical laboratories.
Nada Molaae +4 more
doaj +2 more sources
The MTT Assay: Utility, Limitations, Pitfalls, and Interpretation in Bulk and Single-Cell Analysis. [PDF]
Int J Mol Sci, 2021 The MTT assay for cellular metabolic activity is almost ubiquitous to studies of cell toxicity; however, it is commonly applied and interpreted erroneously.
Ghasemi M +3 more
europepmc +2 more sources
J Conserv Dent, 2023 Aim: The aim of this study was to compare the cytotoxic effect of calcium silicate-based Bio-C, CeraSeal, and mineral trioxide aggregate (MTA)-based (MTA-Fillapex) sealers to a widely used resin-based sealer (AH Plus) using 3-(4, 5 dimethythiazol-2yl)-2,
Kumar A +5 more
europepmc +2 more sources
Evaluation of the Cytotoxicity of a Newly Developed Obturating Material for Pulpectomy in Primary Teeth Using Embryonic Toxicology, Brine Shrimp Lethality, and MTT Assay: An In Vitro Study. [PDF]
Eur J DentFathima J N +6 more
europepmc +3 more sources
Cytotoxicity of some 1-(2,4-dihydroxyphenyl)-3-(4-phenylpiperidin-1-yl) prop-2-en-1-one derivatives using MTT assay [PDF]
Trends in Pharmaceutical Sciences, 2015 Some N-substituted piperidine structures were synthesized and evaluated for cytotoxic activity against four different cell lines using the standard MTT assay method and Doxorubicin was used as the reference drug.
Farzaneh Fesahat +5 more
doaj +4 more sources
Mitochondrial biogenesis and metabolic hyperactivation limits the application of MTT assay in the estimation of radiation induced growth inhibition. [PDF]
Sci Rep, 2018 Metabolic viability based high throughput assays like MTT and MTS are widely used in assessing the cell viability. However, alteration in both mitochondrial content and metabolism can influence the metabolic viability of cells and radiation is a ...
Rai Y +8 more
europepmc +2 more sources
In vitro Cell Viability by CellProfiler® Software as Equivalent to MTT Assay. [PDF]
Pharmacogn Mag, 2017 Objective: This study evaluated in vitro cell viability by the colorimetric MTT stands for 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (3-(4, 5-dimethylthiazolyl-2)-2, 5-diphenyltetrazolium bromide) (3-(4, 5-dimethylthiazolyl-2)-2, 5 ...
Gasparini LS +9 more
europepmc +2 more sources
Effects of E407a on the viability, metabolic and functional activity of dermal fibroblasts [PDF]
Ķazaķstannyṇ Klinikalyķ Medicinasy, 2021 Aim. To evaluate the effects of semi-refined carrageenan (E407a) on the viability, metabolic and functional activity of skin fibroblasts in vitro. Materials and methods.
Anton Tkachenko +3 more
doaj +1 more source