Results 141 to 150 of about 21,265 (190)
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MUC1 and the Immunobiology of Cancer
Journal of Mammary Gland Biology and Neoplasia, 2002The membrane epithelial mucin MUC1 is expressed at the luminal surface of most simple epithelial cells, but expression is greatly increased at lactation and in most breast carcinomas. The increase in level of expression of MUC1 in breast cancer is accompanied by changes in the profile of glycosyl transferases involved in the synthesis of the O-glycans ...
Taylor-Papadimitriou, J +6 more
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MUC1, The Renaissance Molecule
Journal of Mammary Gland Biology and Neoplasia, 2001MUC1 is a large, heavily glycosylated mucin expressed on the apical surfaces of most simple, secretory epithelia including the mammary gland, gastrointestinal, respiratory, urinary and reproductive tracts. Although MUC1 was thought to be an epithelial-specific protein, it is now known to be expressed on a variety of hematopoietic cells as well.
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Nature Reviews Cancer, 2012
The UK press got carried away with a cancer story this week. It seems that a universal cancer vaccine is on its way, despite the fact that it has only been trialled in ten patients (with five more still to be recruited).
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The UK press got carried away with a cancer story this week. It seems that a universal cancer vaccine is on its way, despite the fact that it has only been trialled in ten patients (with five more still to be recruited).
openaire +1 more source
Expression of MUC1 in tubal pregnancy
Fertility and Sterility, 2008The MUC1 mucin is normally expressed in the epithelium of the fallopian tube, and its expression on the epithelium of the tubes with ectopic pregnancies has not been studied. The mean (+/- SEM) histologic score for MUC1 was 1.4 +/- 0.2 in the luminal epithelium of tubes with ectopic pregnancies, and the histologic score for normal tubes was 2.8 +/- 0.2;
Ricardo Francalacci, Savaris +3 more
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BJU International, 2003
OBJECTIVE To detect the expression and transcription pattern of MUC1 in benign and malignant disease, and in two widely studied cell lines, and to investigate the glycosylation of MUC‐1 in bone metastasis of prostate cancer, as mucins have been implicated in the progression and behaviour of several cancers.
I C, Schut +6 more
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OBJECTIVE To detect the expression and transcription pattern of MUC1 in benign and malignant disease, and in two widely studied cell lines, and to investigate the glycosylation of MUC‐1 in bone metastasis of prostate cancer, as mucins have been implicated in the progression and behaviour of several cancers.
I C, Schut +6 more
openaire +2 more sources
Bortezomib resistance and MUC1 in myeloma
Blood, 2014In this issue of Blood , Yin et al make the novel discovery that targeting the mucin 1 C-terminal subunit (MUC1-C) oncoprotein reverses resistance to the proteasome inhibitor bortezomib in multiple myeloma cells by triggering depletion of glutathione (GSH) pools and induction of oxidative injury.
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MUC1: Structure, Function, and Clinic Application in Epithelial Cancers
International Journal of Molecular Sciences, 2021Zhang Shiqing, Joshua Ko, Zhang Zhu
exaly
A review on development of MUC1-based cancer vaccine
Biomedicine and Pharmacotherapy, 2020Han Lei, Tong Gao
exaly

