Results 11 to 20 of about 21,265 (190)
MUC1 and endometrial receptivity [PDF]
Molecular Human Reproduction, 1998 Mucins, best known as the major constituent of mucus, are a family of highly glycosylated, high molecular weight (> or = 200 kDa) glycoproteins present on the surface of human epithelial cells. MUC1 has the features of an integral membrane protein. It has an extracellular tandem repeat domain that forms the major part of the core protein, and results ...
M, Meseguer, A, Pellicer, C, Simón
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MUC1 in hematological malignancies [PDF]
Leukemia & Lymphoma, 2016 Mucin1 (MUC1) is a transmembrane oncogenic protein that plays a central role in malignant transformation and disease evolution, including cell proliferation, survival, self-renewal, and metastatic invasion. MUC1 has been shown to interact with diverse effectors such as β-catenin, receptor tyrosine kinases, and c-Abl, which are of importance in the ...
Dina, Stroopinsky +2 more
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Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1999 The MUC1 membrane mucin was first identified as the molecule recognised by mouse monoclonal antibodies directed to epithelial cells, and the cancers which develop from them. Cloning the gene showed that the extracellular domain is made up of highly conserved repeats of 20 amino acids, the actual number varying between 25 and 100 depending on the allele.
Taylor-Papadimitriou, J +3 more
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Indian Journal of Allergy Asthma and Immunology, 2021 BACKGROUND: Asthma is a chronic disease that affects large number of people worldwide. In urban areas, asthmatic people are getting exposed to pigeon antigen (droppings and feathers) around the workplace and domestic areas.
Anil Kumar Mavi +5 more
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Human Vaccines & Immunotherapeutics, 2021 The prognosis of patients with advanced pancreatic cancer is poor despite the recent introduction of immune checkpoint inhibitors. Therefore, the development of new therapeutic approaches is urgently required.
Shuichi Ota +3 more
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Optical Aptamer Probes of Fluorescent Imaging to Rapid Monitoring of Circulating Tumor Cell
Sensors, 2016 Fluorescence detecting of exogenous EpCAM (epithelial cell adhesion molecule) or muc1 (mucin1) expression correlated to cancer metastasis using nanoparticles provides pivotal information on CTC (circulating tumor cell) occurrence in a noninvasive tool ...
Ji Yeon Hwang +4 more
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MUC1: Antibodies and Immunoassays
Tumor Biology, 2001 High molecular weight mucins represent a unique challenge as tumor markers by virtue of their complex array of epitopes. The list is dominated by the high molecular weight mucins MUC1, CEA and CA125. While the currently accepted role for these tumor markers is in the prediction and detection of relapse, it is possible that their sensitivity and ...
Rye, Phil D., McGuckin, Michael A.
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Molecular Cancer, 2006 Background The MUC1 gene encodes a mucin glycoprotein(s) which is basally expressed in most epithelial cells. In breast adenocarcinoma and a variety of epithelial tumors its transcription is dramatically upregulated.
Wreschner Daniel H +5 more
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Türk Patoloji Dergisi, 2023 Objective: Lung adenocarcinomas are divided into acinar, lepidic, papillary, micropapillary, and solid predominant subtypes according to the current World Health Organization (WHO) classification.
Melek BUYUK +5 more
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PLoS Pathogens, 2009 The bacterium Helicobacter pylori can cause peptic ulcer disease, gastric adenocarcinoma and MALT lymphoma. The cell-surface mucin MUC1 is a large glycoprotein which is highly expressed on the mucosal surface and limits the density of H.
Sara K Lindén +7 more
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