Results 11 to 20 of about 28,581 (233)
Detection of Circulating Mammary Mucin (MUC1) and MUC1 Immune Complexes (MUC1-CIC) in Healthy Women [PDF]
The International Journal of Biological Markers, 2001 There is convincing epidemiological evidence that multiparity provides protection against the development of breast cancer. In the present study we evaluated the levels of MUC1 and MUC1 circulating immune complexes (MUC1-CIC) in 135 serum samples ...
M.V. Croce +3 more
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Suppression of MUC1-Overexpressing Tumors by a Novel MUC1/CD3 Bispecific Antibody
Antibodies, 2023 Mucin1 (MUC1) is abnormally glycosylated and overexpressed in a variety of epithelial cancers and plays a critical role in tumor progression. MUC1 has received remark attention as an oncogenic molecule and is considered a valuable tumor target for ...
Jun Fang, Shifa Lai, Haoyang Yu, Lan Ma
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RETRACTION: Recombinant Nanobody Against Muc1 Tandem Repeats Inhibits Growth, Invasion, Metastasis, and Vascularization of Spontaneous Mouse Mammary Tumors. [PDF]
Mol OncolRETRACTION: P. Merikhian, B. Darvishi, N. Jalili, M. R. Esmailinejad, A. S. Khatibi, S. M. Kalbolandi, M. Salehi, M. Mosayebzadeh, M. S. Barough, K. Majidzadeh‐A, F. Yadegari, F. Rahbarizadeh, and L. Farahmand, “Recombinant Nanobody Against Muc1 Tandem Repeats Inhibits Growth, Invasion, Metastasis, and Vascularization of Spontaneous Mouse Mammary ...
europepmc +2 more sources
MUC1 expressing tumor growth was retarded after human mucin 1 (MUC1) plasmid DNA immunization [PDF]
, 2022 INTRODUCTION: Naked DNA is one of the attractive tools for vaccination studies. We studied naked DNA vaccination against the human tumor antigen, mucin, which is encoded by the MUC1 gene.
Jeong, Hwan-Kyu +7 more
core +1 more source
MUC1 and endometrial receptivity [PDF]
Molecular Human Reproduction, 1998 Mucins, best known as the major constituent of mucus, are a family of highly glycosylated, high molecular weight (> or = 200 kDa) glycoproteins present on the surface of human epithelial cells. MUC1 has the features of an integral membrane protein. It has an extracellular tandem repeat domain that forms the major part of the core protein, and results ...
M, Meseguer, A, Pellicer, C, Simón
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Human Vaccines & Immunotherapeutics, 2021 The prognosis of patients with advanced pancreatic cancer is poor despite the recent introduction of immune checkpoint inhibitors. Therefore, the development of new therapeutic approaches is urgently required.
Shuichi Ota +3 more
doaj +1 more source
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1999 The MUC1 membrane mucin was first identified as the molecule recognised by mouse monoclonal antibodies directed to epithelial cells, and the cancers which develop from them. Cloning the gene showed that the extracellular domain is made up of highly conserved repeats of 20 amino acids, the actual number varying between 25 and 100 depending on the allele.
Taylor-Papadimitriou, J +3 more
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MUC1 in hematological malignancies [PDF]
Leukemia & Lymphoma, 2016 Mucin1 (MUC1) is a transmembrane oncogenic protein that plays a central role in malignant transformation and disease evolution, including cell proliferation, survival, self-renewal, and metastatic invasion. MUC1 has been shown to interact with diverse effectors such as β-catenin, receptor tyrosine kinases, and c-Abl, which are of importance in the ...
Dina, Stroopinsky +2 more
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Türk Patoloji Dergisi, 2023 Objective: Lung adenocarcinomas are divided into acinar, lepidic, papillary, micropapillary, and solid predominant subtypes according to the current World Health Organization (WHO) classification.
Melek BUYUK +5 more
doaj +1 more source
MUC1: Antibodies and Immunoassays
Tumor Biology, 2001 High molecular weight mucins represent a unique challenge as tumor markers by virtue of their complex array of epitopes. The list is dominated by the high molecular weight mucins MUC1, CEA and CA125. While the currently accepted role for these tumor markers is in the prediction and detection of relapse, it is possible that their sensitivity and ...
Rye, Phil D., McGuckin, Michael A.
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