Results 31 to 40 of about 28,581 (233)

Expresión de mucinas y moléculas relacionadas en los carcinomas mucoepidermoides de glándulas salivales: implicaciones diagnósticas y pronósticas [PDF]

, 2011
[spa] El carcinoma mucoepidermoide, es el tumor maligno más frecuente de glándulas salivales (GS). Tanto su expresión de mucinas, MUC1 y MUC4, como el número de copias del gen EGFR (receptor del Factor de Crecimiento Epidérmico) y la expresión de pERK1/2
Luján, Blanca Noemí
core   +4 more sources

Regulation of Mucin 1 and multidrug resistance protein 1 by Neuraminidase 1 alters the cytotoxic effects of doxorubicin in breast cancer cells [PDF]

World Cancer Research Journal
Objective: Elevated expression of Multidrug Resistance Protein 1 (MRP1) has been associated with poor prognosis among breast cancer patients. Chemotherapeutic drugs such as doxorubicin (DOX) are substrates of MRP1 that efflux the drug, conferring drug ...
P. Thulasiraman, K. Kerr, A. Wistner
doaj   +1 more source

MUC1-TM and MUC1-ARF expression in normal human kidney and pancreas.

, 2016
Serial sections of paraffin-embedded human pancreatic and renal tissues were immunohistochemically stained with anti-MUC1-TM SEA module antibodies (anti-MUC1-TM [DMB5F3]) and anti-MUC1-ARF antibodies (anti-MUC1-ARF [MPR2G10]) as indicated.
John Hilkens (412442), Michael Chalick (3234639), Franz-Georg Hanisch (318572), Armand Bensussan (214677), Oded Jacobi (3234645), Nechama I. Smorodinsky (140867), Tania Zehavi (367263), Ravit Ziv (3234648), Christian Garbar (3234657), Alan Meeker (3234642), Daniel H. Wreschner (3234654), Edward Pichinuk (3234651), Daniel B. Rubinstein (3234636)   +12 more
core   +1 more source

Stabilizing Functional Nucleic Acids for Real‐Sample Diagnostics

Angewandte Chemie, EarlyView.
Functional nucleic acids enable programmable real‐sample diagnostics, but often lose function in complex biological matrices. This review highlights four stabilization levers—chemical, topological, architectural, and microenvironment/interface engineering—that preserve aptamer and DNAzyme performance in saliva, serum, urine, and stool, reframing ...
Soyeon Lee, Letizia Dondi, Amal Mathai, Connor Nurmi, Yingfu Li   +4 more
wiley   +2 more sources

Detection of nuclear MUC1-ARF protein with polyclonal anti-MUC1-ARF antibodies and with three distinct anti-MUC1-ARF monoclonal antibodies, MPR2G10, MPR4B3 and MPR5C9.

, 2016
(A) Polyclonal anti-MUC1-ARF antibodies and (B) three independently isolated anti-MUC1-ARF monoclonal antibodies, MPR2G10, MPR4B3 and MPR5C9, were reacted in the presence of competing ARF peptide (B, panels 4), in its absence (B, panels 2), or with a non-
John Hilkens (412442), Michael Chalick (3234639), Franz-Georg Hanisch (318572), Armand Bensussan (214677), Oded Jacobi (3234645), Nechama I. Smorodinsky (140867), Tania Zehavi (367263), Ravit Ziv (3234648), Christian Garbar (3234657), Alan Meeker (3234642), Daniel H. Wreschner (3234654), Edward Pichinuk (3234651), Daniel B. Rubinstein (3234636)   +12 more
core   +1 more source

Functional site analysis of mucin 1 in regulating the malignant characteristics of tumor cells

Shanghai Jiaotong Daxue xuebao. Yixue ban
Objective·To identify the functional motifs of mucin 1 (MUC1) involved in regulating tumor cell proliferation, migration, and stemness maintenance.Methods·Mutational characteristics of the MUC1 gene across different cancers were identified from The ...
GAO Kexing, LIAO Chunhua, LI Shengze, MA Shuangyu, HUANG Lei   +4 more
doaj   +1 more source

Membrane-Tethered Mucin 1 Is Stimulated by Interferon and Virus Infection in Multiple Cell Types and Inhibits Influenza A Virus Infection in Human Airway Epithelium

mBio, 2022
Influenza A virus (IAV) causes significant morbidity and mortality in the human population. Tethered mucin 1 (MUC1) is highly expressed in airway epithelium, the primary site of IAV replication, and also by other cell types that influence IAV infection ...
Ethan Iverson, Kira Griswold, Daniel Song, Talita B. Gagliardi, Kajal Hamidzadeh, Mehmet Kesimer, Sanju Sinha, Melissa Perry, Gregg A. Duncan, Margaret A. Scull   +9 more
doaj   +1 more source

MUC1-TM and MUC1-ARF proteins are expressed solely in the exocrine pancreas and not in the endocrine pancreatic islets.

, 2016
Serial sections of paraffin-embedded human pancreatic tissues were immunohistochemically stained with anti-MUC1-TM SEA module antibodies (anti-MUC1-TM [DMB5F3]), anti-MUC1-ARF antibodies (anti-MUC1-ARF [MPR2G10]) and normal mouse immunoglobulin as ...
John Hilkens (412442), Michael Chalick (3234639), Franz-Georg Hanisch (318572), Armand Bensussan (214677), Oded Jacobi (3234645), Nechama I. Smorodinsky (140867), Tania Zehavi (367263), Ravit Ziv (3234648), Christian Garbar (3234657), Alan Meeker (3234642), Daniel H. Wreschner (3234654), Edward Pichinuk (3234651), Daniel B. Rubinstein (3234636)   +12 more
core   +1 more source

Mucin 1 promotes salivary gland cancer cell proliferation and metastasis by regulating the epidermal growth factor receptor signaling pathway

Journal of Dental Sciences, 2023
Background/purpose: Salivary gland cancer (SGC) is the common malignant tumor of the head and neck region with poor prognosis. Mucin 1 (MUC1) has been reported to be associated with the development of cancer.
Hao Lu, Wan-Lin Xu, Yi-Fan Wu, Wen-Jun Yang, Sheng-Wen Liu   +4 more
doaj   +1 more source

MUC1-ARF protein is observed only in those human cell lines that express the MUC1 gene.

, 2016
Lysates prepared from human cell lines A431, MCF7, KB, SY5Y, HK293 and U87 (Panels 'A' to 'E') were resolved on SDS-PAGE, western blotted, and probed with anti-MUC1-ARF MPR2G10. MUC1-ARF protein is indicated by the filled red arrowheads.
John Hilkens (412442), Michael Chalick (3234639), Franz-Georg Hanisch (318572), Armand Bensussan (214677), Oded Jacobi (3234645), Nechama I. Smorodinsky (140867), Tania Zehavi (367263), Ravit Ziv (3234648), Christian Garbar (3234657), Alan Meeker (3234642), Daniel H. Wreschner (3234654), Edward Pichinuk (3234651), Daniel B. Rubinstein (3234636)   +12 more
core   +1 more source