Results 51 to 60 of about 27,684 (225)

MUC1/SEC and MUC1/Y overexpression is associated with inflammation in Sjogren's syndrome [PDF]

, 2015
Artículo de publicación ISIOBJECTIVES: To evaluate the expression and localization of MUC1/SEC and MUC1/Y isoforms in labial salivary glands (LSG) from Sj€ogren’s syndrome patients (SS patients), as well as their in vitro expression induced by ...
Hermoso Ramello, Marcela, Alliende, C., Smorodinsky, N. I., Alliende, Cecilia, Leyton, C., Castro, I., Leyton Martínez, Cecilia, Urzúa, U., Barrera, María José, Bahamondes Lorca, Verónica, González Burgos, María Julieta, Quest, Andrew F. G., Bahamondes, V., Sung, H. H., Molina, C., Urzúa Tobar, Ulises, González, S., Herrera Cisterna, Luisa, Molina, Claudio, Cortés, J., Barrera, M. J., Aguilera, S., Herrera, L., Sung Hsieh, Hsiao, González, M. J.   +24 more
core   +2 more sources

MUC1-ARF protein is observed only in those human cell lines that express the MUC1 gene.

, 2016
Lysates prepared from human cell lines A431, MCF7, KB, SY5Y, HK293 and U87 (Panels 'A' to 'E') were resolved on SDS-PAGE, western blotted, and probed with anti-MUC1-ARF MPR2G10. MUC1-ARF protein is indicated by the filled red arrowheads.
John Hilkens (412442), Michael Chalick (3234639), Franz-Georg Hanisch (318572), Armand Bensussan (214677), Oded Jacobi (3234645), Nechama I. Smorodinsky (140867), Tania Zehavi (367263), Ravit Ziv (3234648), Christian Garbar (3234657), Alan Meeker (3234642), Daniel H. Wreschner (3234654), Edward Pichinuk (3234651), Daniel B. Rubinstein (3234636)   +12 more
core   +1 more source

Analysis of Epithelial Growth Factor-Receptor (EGFR) Phosphorylation in Uterine Smooth Muscle Tumors [PDF]

, 2013
Uterine fibroids are the commonest uterine benign tumors. A potential mechanism of malignant transformation from leiomyomas to leiomyosarcomas has beendescribed.
Darius Dian, Antonis Makrigiannakis, Jeschke, Udo, Klaus Friese, Weissenbacher, Tobias, Mayr, Doris, David Roeder, Udo Jeschke, Nina Ditsch, Thomas Vrekoussis, Tobias Weissenbacher, Vrekoussis, Thomas, Dian, Darius, Ditsch, Nina, Friese, Klaus, Doris Mayr, Makrigiannakis, Antonis, Roeder, David   +17 more
core   +1 more source

MUC1 expressing tumor growth was retarded after human mucin 1 (MUC1) plasmid DNA immunization [PDF]

, 2022
INTRODUCTION: Naked DNA is one of the attractive tools for vaccination studies. We studied naked DNA vaccination against the human tumor antigen, mucin, which is encoded by the MUC1 gene.
Jeong, Hwan-Kyu, Apostolopoulos, Vasso, Son, Hye-Youn, Kim, Chul-Woo   +3 more
core   +1 more source

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave, Ashish B. Jadhav, Nitin B. Waghamode, Shubham Khot, Rajiya Khan, Ravi Hole, Shankar M. Dhobale, Manoj Aswar, Keshav Raj Paudel   +8 more
wiley   +1 more source

MUC1-C is a master regulator of MICA/B NKG2D ligand and exosome secretion in human cancer cells

Journal for ImmunoTherapy of Cancer, 2023
Background The MUC1-C protein evolved in mammals to protect barrier tissues from loss of homeostasis; however, MUC1-C promotes oncogenesis in association with chronic inflammation. Aberrant expression of MUC1-C in cancers has been linked to depletion and
Satoshi Ishikawa, Donald Kufe, Constantine Mitsiades, Nami Yamashita, Atsushi Fushimi, Atrayee Bhattacharya, Yoshihiro Morimoto, Tatsuaki Daimon, Haruka Hirose, Shizuka Yamano, Naoki Haratake, Rehan Ahmad, Hidekazu Takahashi, Olga Dashevsky   +13 more
doaj   +1 more source

Optical Detection of Cellular Signals at Material Interfaces

Advanced Healthcare Materials, EarlyView.
Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.
Xuchen Ren, Jitong Ren, Zixin Zhang, Koney Eungkon Kim, Francis L. Hong, Yuecheng Peter Zhou   +5 more
wiley   +1 more source

MUC1-targeted CAR-T cell secreted anti-PD-1 IgG antibody enhances antitumor activity in Cholangiocarcinoma. [PDF]

Sci Rep
Cholangiocarcinoma (CCA) is a highly aggressive malignancy with poor prognosis and limited therapeutic options. Gene expression analysis of patient samples and flow cytometry of CCA cell lines demonstrated significant upregulation of MUC1 and PD-L1 ...
Khuisangeam N, Chinsuwan T, Intanachai T, Thaiwong R, Boonkrai C, Phakham T, Pisitkun T, Suppipat K, Hirankarn N, Tawinwung S.   +9 more
europepmc   +2 more sources

Immunotherapy with mannan-MUC1 and IL-12 in MUC1 transgenic mice

Vaccine, 2000
Mice immunised with oxidised mannan-MUC1 fusion protein (M-FP) develop MHC restricted CD8(+) cytotoxic T cells. We now demonstrate that in MUC1/HLA-A2 transgenic mice, IL-12 gives enhanced CTL, CTLp and tumor protection. CTLp in MUC1 transgenic mice with M-FP were 1/55,000, and with IL-12, this increased to 1/19,000, with improved tumor protection ...
Lees, Catherine, Apostolopoulos, Vasso, Acres, Bruce, Ramshaw, Ian, Ramsay, Alistair, Ong, Cheng Soon, McKenzie, Ian F C   +6 more
openaire   +2 more sources

MUC1 is a receptor for the Salmonella SiiE adhesin that enables apical invasion into enterocytes [PDF]

, 2019
The cellular invasion machinery of the enteric pathogen Salmonella consists of a type III secretion system (T3SS) with injectable virulence factors that induce uptake by macropinocytosis. Salmonella invasion at the apical surface of intestinal epithelial
dI&I I&I-2, Richard W. Wubbolts (3797863), LS Celbiologie-Algemeen, Afd Chemical Biology and Drug Discovery, Karin Strijbis, Nancy M. C. Bleumink-Pluym (132115), Luijkx, Yvette M. C. A., Richard W Wubbolts, Strijbis, Karin, Jos P. M. van Putten (103913), Sub Center for Cell Imaging, Jos P M van Putten, Wubbolts, Richard W., Bleumink-Pluym, Nancy M. C., Yvette M. C. A. Luijkx (6294311), Faculteit Diergeneeskunde, dB&C I&I, Karin Strijbis (352877), van Putten, Jos P. M., LS Infectiebiologie (Bacteriologie), Xinyue Li, Nancy M C Bleumink-Pluym, Xinyue Li (628935), Li, Xinyue, Yvette M C A Luijkx   +24 more
core   +1 more source