Results 41 to 50 of about 27,684 (225)

MUC1 as a putative prognostic marker for prostate cancer [PDF]

, 2008
MUC1 is expressed on the apical surface of glandular epithelium. With functions including protection, adhesion and signaling, MUC1 has been implicated in prostate cancer. There are many splice variants, the best characterized of which are MUC1/1 and MUC1/
Monica Nistér, Henrik Grönberg, Brismar, Kerstin, Nistér, Monica, Grönberg, Henrik, Rona J Strawbridge, Strawbridge, Rona J., Li, Chunde, Kerstin Brismar, Chunde Li   +9 more
core   +1 more source

Novel MUC1 aptamer selectively delivers cytotoxic agent to cancer cells in vitro. [PDF]

PLoS ONE, 2012
Chemotherapy is a primary treatment for cancer, but its efficacy is often limited by the adverse effects of cytotoxic agents. Targeted drug delivery may reduce the non-specific toxicity of chemotherapy by selectively directing anticancer drugs to tumor ...
Yan Hu, Jinhong Duan, Qimin Zhan, Fengdan Wang, Xin Lu, Xian-Da Yang   +5 more
doaj   +1 more source

Steroidal but not embryonic regulation of mucin 1 expression in bovine endometrium

The Journal of Reproduction and Development, 2021
In cow herd management, inadequate embryo implantation leads to pregnancy loss and causes severe economic losses. Thus, it is crucial to understand the molecular mechanisms underlying endometrial receptivity and subsequent embryo implantation ...
Kaiyu KUBOTA, Masafumi MIWA, Ken-Go HAYASHI, Misa HOSOE, Miki SAKATANI   +4 more
doaj   +1 more source

Detection of nuclear MUC1-ARF protein with polyclonal anti-MUC1-ARF antibodies and with three distinct anti-MUC1-ARF monoclonal antibodies, MPR2G10, MPR4B3 and MPR5C9.

, 2016
(A) Polyclonal anti-MUC1-ARF antibodies and (B) three independently isolated anti-MUC1-ARF monoclonal antibodies, MPR2G10, MPR4B3 and MPR5C9, were reacted in the presence of competing ARF peptide (B, panels 4), in its absence (B, panels 2), or with a non-
John Hilkens (412442), Michael Chalick (3234639), Franz-Georg Hanisch (318572), Armand Bensussan (214677), Oded Jacobi (3234645), Nechama I. Smorodinsky (140867), Tania Zehavi (367263), Ravit Ziv (3234648), Christian Garbar (3234657), Alan Meeker (3234642), Daniel H. Wreschner (3234654), Edward Pichinuk (3234651), Daniel B. Rubinstein (3234636)   +12 more
core   +1 more source

MUC1-TM and MUC1-ARF expression in normal human kidney and pancreas.

, 2016
Serial sections of paraffin-embedded human pancreatic and renal tissues were immunohistochemically stained with anti-MUC1-TM SEA module antibodies (anti-MUC1-TM [DMB5F3]) and anti-MUC1-ARF antibodies (anti-MUC1-ARF [MPR2G10]) as indicated.
John Hilkens (412442), Michael Chalick (3234639), Franz-Georg Hanisch (318572), Armand Bensussan (214677), Oded Jacobi (3234645), Nechama I. Smorodinsky (140867), Tania Zehavi (367263), Ravit Ziv (3234648), Christian Garbar (3234657), Alan Meeker (3234642), Daniel H. Wreschner (3234654), Edward Pichinuk (3234651), Daniel B. Rubinstein (3234636)   +12 more
core   +1 more source

MUC1-TM and MUC1-ARF proteins are expressed solely in the exocrine pancreas and not in the endocrine pancreatic islets.

, 2016
Serial sections of paraffin-embedded human pancreatic tissues were immunohistochemically stained with anti-MUC1-TM SEA module antibodies (anti-MUC1-TM [DMB5F3]), anti-MUC1-ARF antibodies (anti-MUC1-ARF [MPR2G10]) and normal mouse immunoglobulin as ...
John Hilkens (412442), Michael Chalick (3234639), Franz-Georg Hanisch (318572), Armand Bensussan (214677), Oded Jacobi (3234645), Nechama I. Smorodinsky (140867), Tania Zehavi (367263), Ravit Ziv (3234648), Christian Garbar (3234657), Alan Meeker (3234642), Daniel H. Wreschner (3234654), Edward Pichinuk (3234651), Daniel B. Rubinstein (3234636)   +12 more
core   +1 more source

Glycosylation pattern of brush border-associated glycoproteins in enterocyte-like cells: involvement of complex-type N-glycans in apical trafficking [PDF]

, 2009
We have previously reported that galectin-4, a tandem repeat-type galectin, regulates the raft-dependent delivery of glycoproteins to the apical brush border membrane of enterocyte-like HT-29 cells.
Huet, Guillemette, Stechly, Laurence, André, Sabine, Seuningen, Isabelle Van, van Seuningen, Isabelle, Gabius, Hans-Joachim, Morelle, Willy, Michalski, Jean-Claude, Porchet, Nicole   +8 more
core   +1 more source

Functional site analysis of mucin 1 in regulating the malignant characteristics of tumor cells

Shanghai Jiaotong Daxue xuebao. Yixue ban
Objective·To identify the functional motifs of mucin 1 (MUC1) involved in regulating tumor cell proliferation, migration, and stemness maintenance.Methods·Mutational characteristics of the MUC1 gene across different cancers were identified from The ...
GAO Kexing, LIAO Chunhua, LI Shengze, MA Shuangyu, HUANG Lei   +4 more
doaj   +1 more source

MUC1 modulates gastric epithelial immune response to bacteria or inflammatory stimuli

Universa Medicina, 2015
BACKGROUND Cell surface mucin glycoproteins are expressed on the mucosal surface. One of these cell surface mucins is mucin-1 (MUC1), which plays a role as a physical barrier and limits inflammation.
Shofyatul Y. Triyana, Yong H. Sheng, Michael McGuckin   +2 more
doaj   +1 more source

Mucin 1 promotes salivary gland cancer cell proliferation and metastasis by regulating the epidermal growth factor receptor signaling pathway

Journal of Dental Sciences, 2023
Background/purpose: Salivary gland cancer (SGC) is the common malignant tumor of the head and neck region with poor prognosis. Mucin 1 (MUC1) has been reported to be associated with the development of cancer.
Hao Lu, Wan-Lin Xu, Yi-Fan Wu, Wen-Jun Yang, Sheng-Wen Liu   +4 more
doaj   +1 more source