Results 21 to 30 of about 28,581 (233)
The research status and prospects of MUC1 in immunology
Human Vaccines & Immunotherapeutics, 2023 In immune processes, molecular – molecular interactions are complex. As MUC1 often appears to be an important molecule in inflammation and tumor immunity, it is necessary to summarize the leading countries, authors, journals, and the cooperation among ...
Linna Long +7 more
doaj +1 more source
Optical Aptamer Probes of Fluorescent Imaging to Rapid Monitoring of Circulating Tumor Cell
Sensors, 2016 Fluorescence detecting of exogenous EpCAM (epithelial cell adhesion molecule) or muc1 (mucin1) expression correlated to cancer metastasis using nanoparticles provides pivotal information on CTC (circulating tumor cell) occurrence in a noninvasive tool ...
Ji Yeon Hwang +4 more
doaj +1 more source
BMC Cancer, 2006 Background HNSCC progression to adjacent tissue and nodes may be mediated by altered glycoproteins and glycolipids such as MUC1 mucin. This report constitutes a detailed statistical study about MUC1 expression and anti-MUC1 immune responses in relation ...
Segal-Eiras Amada +3 more
doaj +1 more source
MUC1 modulates gastric epithelial immune response to bacteria or inflammatory stimuli
Universa Medicina, 2015 BACKGROUND Cell surface mucin glycoproteins are expressed on the mucosal surface. One of these cell surface mucins is mucin-1 (MUC1), which plays a role as a physical barrier and limits inflammation.
Shofyatul Y. Triyana +2 more
doaj +1 more source
American Journal of Respiratory Cell and Molecular Biology, 2008 Abstract MUC1 is a membrane-tethered mucin expressed on the surface of epithelial cells lining mucosal surfaces. Recent studies have begun to elucidate the physiologic function of MUC1 in the airways, pointing to an antiinflammatory role that is initiated late in the course of bacterial infection and is mediated through inhibition of ...
K. Chul Kim, Erik P. Lillehoj
openaire +1 more source
Amplified Detection of Breast Cancer Autoantibodies Using MUC1-Based Tn Antigen Mimics [PDF]
, 2020 In many human carcinomas, mucin-1 (MUC1) is overexpressed and aberrantly glycosylated, resulting in the exposure of previously hidden antigens. This generates new patient antibody profiles that can be used in cancer diagnosis.
Hinou, Hiroshi [0000-0003-2223-7300] +15 more
core +1 more source
Cell Death and Disease, 2022 Mitophagy is a vital process that controls mitochondria quality, dysregulation of which can promote cancer. Oncoprotein mucin 1 (MUC1) targets mitochondria to attenuate drug-induced apoptosis.
Quanfu Li +11 more
doaj +1 more source
Steroidal but not embryonic regulation of mucin 1 expression in bovine endometrium
The Journal of Reproduction and Development, 2021 In cow herd management, inadequate embryo implantation leads to pregnancy loss and causes severe economic losses. Thus, it is crucial to understand the molecular mechanisms underlying endometrial receptivity and subsequent embryo implantation ...
Kaiyu KUBOTA +4 more
doaj +1 more source
MUC1-C promotes the suppressive immune microenvironment in non-small cell lung cancer
OncoImmunology, 2017 The cancer immune microenvironment is of importance for the effectiveness of immunotherapy; however, its dysregulation is poorly understood. The MUC1-C oncoprotein is aberrantly overexpressed in non-small cell lung cancer (NSCLC) and has been linked to ...
Audrey Bouillez +8 more
doaj +1 more source
A ROS‐Responsive and Mucoadhesive Thermosensitive Hydrogel Encapsulated with Mizoribine for Synergistic Dry Eye Therapy [PDF]
Advanced scienceThe ROS‐responsive in situ thermosensitive MZR@SPPP hydrogel system enables dual‐stage drug loading and sustained ocular delivery. Upon administration, it gelates at ocular surface temperature, enhancing ocular adhesion. By scavenging free radicals, restoring NRF2‐mediated antioxidant defense and mitochondrial homeostasis, and suppressing inflammatory ...
Qin D +13 more
europepmc +2 more sources