Results 111 to 120 of about 21,687 (212)
MUC5AC (mucin 5AC, oligomeric mucus/gel-forming) [PDF]
, 2010 Review on MUC5AC (mucin 5AC, oligomeric mucus/gel-forming), with data on DNA, on the protein encoded, and where the gene is ...
R Mejías-Luque +5 more
core +1 more source
IL-19 Up-Regulates Mucin 5AC Production in Patients With Chronic Rhinosinusitis via STAT3 Pathway
Frontiers in Immunology, 2019 The mucin gene, MUC5AC, is highly expressed both in chronic respiratory inflammatory diseases and inflammatory bowel disease where mucin secretion is regulated by members of the interleukin IL-20 subfamily. This study was conducted to determine the roles
Xiaoping Lai +12 more
doaj +1 more source
E3 Ubiquitin Ligases in MASH‐Associated Liver Fibrosis: Mechanisms and Therapeutic Opportunities
Liver International, Volume 46, Issue 10, October 2026.ABSTRACT Metabolic dysfunction‐associated steatohepatitis (MASH) is a major cause of progressive liver fibrosis and can ultimately lead to cirrhosis and hepatocellular carcinoma (HCC). MASH‐associated liver fibrosis develops through a complex interplay among lipotoxic hepatocyte injury, oxidative and endoplasmic reticulum stress, inflammatory ...
Ah‐Reum Oh +8 more
wiley +1 more source
Colocalization of MUC5B or MUC5AC and vitronectin.
, 2015 Confocal images showing localization of MUC5B (a) and MUC5AC (b) (green fluorescence), as markers of mucous cells in submucosal glands and epithelial goblet cells, respectively and vitronectin (red fluorescence).
Chun Y. Seow (701652) +6 more
core +1 more source
Multiple regulatory mechanisms of MUC5AC gene expression.
, 2014 (A) Luciferase reporter analysis of a series of constructs covering the far upstream sequence in the MUC5AC promoter. Data represent the mean of luciferase activities in SW480, SH-10-TC, and KE-39 cells measured at 24 h after transfection. The error bars
Kazuya Shiogama (381134) +11 more
core +1 more source
Suppression of MUC5AC expression in human bronchial epithelial cells by interferon-γ [PDF]
, 2016 新潟大学博士（医学）Background: Excessive mucin secretion in the airway is an important feature of airway inflammatory diseases. . MUC5AC expression is regulated by a variety of stimuli such MUC5AC expression is regulated by a variety of stimuli such MUC5AC ...
Oyanagi, Takahito, 50900
core +1 more source
Structural and genetic diversity in the secreted mucins, MUC5AC and MUC5B
The American Journal of Human GeneticsABSTRACT The secreted mucins MUC5AC and MUC5B play critical defensive roles in airway pathogen entrapment and mucociliary clearance by encoding large glycoproteins with variable number tandem repeats (VNTRs). These polymorphic and degenerate protein coding VNTRs make the loci difficult to investigate with short reads.
Elizabeth G. Plender +12 more
openaire +3 more sources
사람 기도점액상피세포에서 저산소 환경에 의한 MUC5AC 유전자의 발현 조절
, 2009 Dept. of Medicine/석사[한글]저산소 환경은 부비동 질환의 주요한 병리 기전의 하나이며 부비동 질환이 발생하면 MUC5AC, MUC5B 등의 점액 발현이 증가 되는 것으로 알려져 있다. HIF-1 (hypoxia-inducible factor-1) 은 잘 알려진 전사인자로서 저산소 환경에서 erythropoietin이나 endothelial growth factor 등 유전자의 전사를 활성화 시킨다.
신우철
core
Clinical Ophthalmology, 2018 Hideki Miyake, Naoto Mori, Hidetoshi Mano, Takahiro Imanaka, Masatsugu Nakamura Research and Development Division, Santen Pharmaceutical Co., Ltd., Osaka, Japan Purpose: Reliable measurement of MUC5AC in human tears is essential for elucidation of the ...
Miyake H +4 more
doaj