Results 101 to 110 of about 21,687 (212)
International Journal of Cancer, Volume 159, Issue 8, Page 1873-1883, 15 October 2026.ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest cancers due to its asymptomatic progression, late‐stage diagnosis, and treatment resistance. Efforts in early detection have centered on identifying imaging features and liquid biopsy biomarkers capable of detecting PDAC and its high‐grade precursors before clinical symptoms ...
Christine Worthington +105 more
wiley +1 more source
Клінічна та профілактична медицинаIntroduction. Determining the cause of postnasal drip syndrome can be quite challenging. Nasal septum deformation has been recognized as one possible factor.
Nataliia V. Babchenko +3 more
doaj +1 more source
MUC5AC mucin gene regulation in pancreatic cancer cells
International Journal of Oncology, 2006 MUC5AC is a secretory mucin normally expressed by the surface mucous cells of the human stomach and in the bronchial tract. It is absent from normal pancreas, but de novo expression of this mucin occurs in early-stage pancreatic intraepithelial neoplasias and in the invasive ductal adenocarcinoma of the pancreas, prompting this study of MUC5AC gene ...
Shingo, Kato +9 more
openaire +3 more sources
Clinical &Experimental Allergy, Volume 55, Issue 3, Page 264-266, March 2025.
Kirsten E. Stewart +3 more
wiley +1 more source
Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.1. Irregular dietary patterns (e.g., late breakfast, reduced meal frequency) upregulate the bai gene cluster by disrupting cholecystokinin (CCK) release rhythms and gut microbiota circadian rhythms, leading to increased production of secondary bile acids, particularly DCA. High‐carbohydrate dietary patterns increase gallstone risk (OR = 1.329).
Rui Li +6 more
wiley +1 more source
HIF-1α is involved in the regulation of MUC5AC expression.
, 2014 When HIF-1α expression is increased, MUC5AC expression is induced; conversely, when HIF-1α expression is decreased, MUC5AC expression is reduced accordingly. (A) Gain-of-function study with mammalian HIF-1α expression vector in NCI-H292 cells. DNA of the
Joo-Heon Yoon (311505) +5 more
core +1 more source
British Journal of Pharmacology, Volume 183, Issue 19, Page 5975-5991, October 2026.Background and Purpose Aspergillus fumigatus (A. fumigatus) exposure causes of severe allergic asthma, characterized by airway inflammation and epithelial dysfunction. TMBIM6 (Bax inhibitor‐1) has been implicated in airway epithelial stress responses and AKT signalling.
Young‐Jin Yu +7 more
wiley +1 more source
Updates in COPD Management: From Inflammatory Pathways to Targeted Therapies
European Journal of Clinical Investigation, Volume 56, Issue 10, October 2026.COPD is a heterogeneous disease driven by overlapping neutrophilic and eosinophilic inflammatory pathways. This review highlights the shift from symptom‐based treatment toward phenotype‐ and biomarker‐directed care. Blood eosinophils, FeNO, and IgE predict corticosteroid responsiveness and identify candidates for biologic therapy.
Sasha Raman +3 more
wiley +1 more source
Niflumic Acid Reduces Histamine-Induced MUC5AC Expression in Human Conjunctival Epithelial Cells
, 2011 Background/Aims: Histamine is an important inflammatory mediator in allergic conjunctivitis. The aim of the present study was to explore whether histamine induced MUC5AC production in human conjunctival epithelial cells (HCECs), and to describe the ...
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Journal of Anatomy, Volume 249, Issue 4, Page 950-969, October 2026.Bioengineered tissue constructs are vital technologies employed in in vitro testing of both fundamental biological principles and industrial screening practices. Current approaches to modelling the nasal mucosa in vitro are not representative and are associated with limitations that impact their reliability and predictive value.
Steven Bradbury +5 more
wiley +1 more source