Results 91 to 100 of about 21,687 (212)

TRPM5-mediated calcium uptake regulates mucin secretion from human colon goblet cells

open access: yeseLife, 2013
Mucin 5AC (MUC5AC) is secreted by goblet cells of the respiratory tract and, surprisingly, also expressed de novo in mucus secreting cancer lines. siRNA-mediated knockdown of 7343 human gene products in a human colonic cancer goblet cell line (HT29-18N2)
Sandra Mitrovic   +10 more
doaj   +1 more source

The characteristics of MUC5AC in the corneal tear film [PDF]

open access: yes, 2000
The mucous layer located on the cornea epithelial surface is mainly composed of mucin.It is unique in being composed of a central protein back bone surrounded by an outermost dense oligosaccharide matrix, yet its pre-cise composition is still unknown ...
김응권
core  

A review of xenobiotic membrane transporter expression within the human placenta: Lessons gained from primary tissue and in vitro methodologies

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A summary of the current knowledge around membrane transporter expression in the most widely used in vitro models of human trophoblasts, including primary placental tissue, cancer cell lines and trophoblast stem cells, as well as the techniques to attempt to mimic the human placenta in vivo.
Rhiannon Pass   +2 more
wiley   +1 more source

Monocyte inflammation augments acrolein-induced Muc5ac expression in mouse lung

open access: yes, 1999
Acrolein, an unsaturated aldehyde found in smog and tobacco smoke, can induce airway hyperreactivity, inflammation, and mucus hypersecretion. To determine whether changes in steady-state mucin gene expression ( Muc2 and Muc5ac) are associated with ...
Steven D. Shapiro   +4 more
core   +1 more source

PGE2 induces MUC2 and MUC5AC expression in human intrahepatic biliary epithelial cells via EP4/p38MAPK activation

open access: yesAnnals of Hepatology, 2013
Background. MUC2 and MUC5AC overproduction is considered to be associated with hepatolithiasis and related to inflammation. However, mechanisms underlying MUC upregulation under inflammatory stimulation in human intrahepatic biliary epithelial cells ...
Yang Li   +3 more
doaj   +1 more source

A combination of cytokeratin 5/6, p63, p40 and MUC5AC are useful for distinguishing squamous cell carcinoma from adenocarcinoma of the cervix

open access: yesDiagnostic Pathology, 2020
Purpose Squamous cell carcinomas and adenocarcinomas are the most common types of cervical cancer. Compared to squamous cell carcinomas, adenocarcinomas are more common in younger women and have a poorer prognosis.
Hailing Li   +6 more
doaj   +1 more source

Early Gastric Cancer Detected During 15‐year Surveillance After Ménétrier Disease Remission and Successfully Treated With Endoscopic Submucosal Dissection: A Case Report

open access: yesDEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Ménétrier disease (MD) was diagnosed based on hypoalbuminemia and giant gastric folds extending from the body to the fundus in a woman in her 70s. A serum anti‐Helicobacter pylori antibody test and urea breath test yielded negative results.
Takaaki Shamoto   +8 more
wiley   +1 more source

Dose‐Related Gastric Toxicity of Diethyl Phthalate in Female Wistar Rats

open access: yesJournal of Applied Toxicology, Volume 46, Issue 11, Page 4242-4254, November 2026.
ABSTRACT Diethyl phthalate (DEP) is commonly used in cosmetics, personal care products, and pharmaceutical formulations as a low‐molecular‐weight phthalate. Despite its widespread use, information on its effects on the gastric mucosa remains limited. This study examined the dose‐related effects of DEP on inflammation, oxidative stress, gastric mucosal ...
Gul Sahika Gokdemir   +5 more
wiley   +1 more source

Novel molecular diagnostic system of limbal stem cell deficiency based on MUC5AC transcript detection in corneal epithelium by PCR-reverse dot blot

open access: yes, 2013
Purpose. To evaluate the sensitivity and specificity of a PCR-strip system based on reverse dot blot for detection of MUC5AC mRNA in corneal epithelium samples from patients with limbal stem cell deficiency (LSCD), and to determine the correlation with ...
Torras, Josep   +12 more
core   +1 more source

The Influence of MUC5AC SNPs on expression of MUC5AC and mucus hypersecretion genes during asthma exacerbations [PDF]

open access: yesJournal of Allergy and Clinical Immunology, 2020
Daniel Jackson   +19 more
openaire   +1 more source

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