Results 31 to 40 of about 133,349 (299)
Bmi-1 regulates mucin levels and mucin O-glycosylation in the submandibular gland of mice.
PLoS ONE, 2021 Mucins, the major components of salivary mucus, are large glycoproteins abundantly modified with O-glycans. Mucins present on the surface of oral tissues contribute greatly to the maintenance of oral hygiene by selectively adhering to the surfaces of ...
Akihiko Kameyama +2 more
doaj +1 more source
Kidney International Reports, 2017 Sequencing peptides included in the urinary proteome identifies the parent proteins and may reveal mechanisms underlying the pathophysiology of chronic kidney disease.
Zhen-Yu Zhang +15 more
doaj +1 more source
Three-dimensional modeling of single stranded DNA hairpins for aptamer-based biosensors. [PDF]
, 2017 Aptamers consist of short oligonucleotides that bind specific targets. They provide advantages over antibodies, including robustness, low cost, and reusability.
Jeddi, Iman, Saiz, Leonor
core +2 more sources
Sensitivity of Human Intrahepatic Cholangiocarcinoma Subtypes to Chemotherapeutics and Molecular Targeted Agents: A Study on Primary Cell Cultures. [PDF]
PLoS ONE, 2015 We investigated the sensitivity of intrahepatic cholangiocarcinoma (IHCCA) subtypes to chemotherapeutics and molecular targeted agents. Primary cultures of mucin- and mixed-IHCCA were prepared from surgical specimens (N.
Alice Fraveto +15 more
doaj +1 more source
, 2021 ABSTRACT Despite extensive research efforts in prostate cancer for the last several decades, the disease remains a leading cause of cancer death in men in the developed world. A typical feature of prostate cancer initiation and progression is the landscape of genetic alterations, which changes the expression patterns of numerous molecules in prostate ...
Kapoor A +5 more
europepmc +3 more sources
Analysis of Epithelial Growth Factor-Receptor (EGFR) Phosphorylation in Uterine Smooth Muscle Tumors [PDF]
, 2013 Uterine fibroids are the commonest uterine benign tumors. A potential mechanism of malignant transformation from leiomyomas to leiomyosarcomas has beendescribed.
Abe +40 more
core +3 more sources
Mucin 1 protects against severeStreptococcus pneumoniaeinfection [PDF]
Virulence, 2017 Streptococcus pneumoniae is a bacterial pathogen that commonly resides in the human nasopharynx, typically without causing any disease. However, in some cases these bacteria migrate from the nasopharynx to other sites of the body such as the lungs and bloodstream causing pneumonia and sepsis, respectively.
Poshmaal Dhar +3 more
openaire +3 more sources
Cancer Reports, 2022 Background Breast cancer is a very common cancer that can be severe if not discovered early. The current tools to detect breast cancer need improvement. Cancer has a universal tendency to affect glycosylation.
Joonas Terävä +8 more
doaj +1 more source
MUC1 positive cutaneous metastasis with transepidermal elimination from a breast carcinoma [PDF]
, 2013 Breast cancer is the most common cause of cutaneous metastases from internal malignancies. Generally, the neoplastic cells are located in the dermis or hypodermis, while a finding of transepidermal elimination on cutaneous metastases is exceptional.
Abba, Martín Carlos +5 more
core +3 more sources
Mucin 1 Regulates Cox-2 Gene in Pancreatic Cancer [PDF]
Pancreas, 2015 Eighty percent of pancreatic ductal adenocarcinomas (PDAs) overexpress mucin 1 (MUC1), a transmembrane mucin glycoprotein. MUC1(high) PDA patients also express high levels of cyclooxygenase 2 (COX-2) and show poor prognosis. The cytoplasmic tail of MUC1 (MUC1-CT) partakes in oncogenic signaling, resulting in accelerated cancer progression.
Nath, Sritama +4 more
openaire +2 more sources