Results 21 to 30 of about 135,393 (265)

Extracellular Protease Activity of Enteropathogenic Escherechia coli on Mucin Substrate

open access: yesHayati Journal of Biosciences, 2007
Enteropathogenic Escherichia coli (EPEC) causes gastrointestinal infections in human. EPEC invasion was initiated by attachment and aggressive colonization on intestinal surface. Attachment of EPEC alter the intestine mucosal cells.
SRI BUDIARTI, NISA RACHMANIA MUBARIK
doaj   +1 more source

Dysregulated Cell–Cell Communication Characterizes Pulmonary Fibrosis

open access: yesCells, 2022
Idiopathic pulmonary fibrosis (IPF) is a progressive disease of older adults characterized by fibrotic replacement of functional gas exchange units in the lung.
Jonathan S. Kurche   +4 more
doaj   +1 more source

Regulated Mucin Secretion from Airway Epithelial Cells

open access: yesFrontiers in Endocrinology, 2013
Secretory epithelial cells of the proximal airways synthesize and secrete gel-forming polymeric mucins. The secreted mucins adsorb water to form mucus that is propelled by neighboring ciliated cells, providing a mobile barrier which removes inhaled ...
Kenneth Bruce Adler   +2 more
doaj   +1 more source

Mucins and the Microbiome [PDF]

open access: yesAnnual Review of Biochemistry, 2020
Generating the barriers that protect our inner surfaces from bacteria and other challenges requires large glycoproteins called mucins. These come in two types, gel-forming and transmembrane, all characterized by large, highly O -glycosylated mucin domains that are diversely decorated by Golgi
openaire   +2 more sources

Advances in the Evaluation of Gastrointestinal Absorption Considering the Mucus Layer

open access: yesPharmaceutics, 2023
Because of the increasing sophistication of formulation technology and the increasing polymerization of compounds directed toward undruggable drug targets, the influence of the mucus layer on gastrointestinal drug absorption has received renewed ...
Kaori Miyazaki   +2 more
doaj   +1 more source

Reduced colonic mucin degradation in breastfed infants colonized by Bifidobacterium longum subsp. infantis EVC001

open access: yesFEBS Open Bio, 2018
Mucin glycoproteins play an important role in protecting the gut epithelium by keeping gut microbes from direct contact with the gut epithelium while allowing for diffusion of small molecules from the lumen to the epithelium.
Sercan Karav   +2 more
doaj   +1 more source

Steroidal but not embryonic regulation of mucin 1 expression in bovine endometrium

open access: yesThe Journal of Reproduction and Development, 2021
In cow herd management, inadequate embryo implantation leads to pregnancy loss and causes severe economic losses. Thus, it is crucial to understand the molecular mechanisms underlying endometrial receptivity and subsequent embryo implantation ...
Kaiyu KUBOTA   +4 more
doaj   +1 more source

Microlithiasis: an important cause of ‘idiopathic’ acute pancreatitis?

open access: yesAnnals of Hepatology, 2003
Microlithiasis is the underlying cause in a significant proportion of patients with ‘idiopathic’ acute pancreatitis. The mechanism appears to be a relative deficiency of phosphatidylcholine in bile, with fast and extensive cholesterol crystallization as ...
Niels G. Venneman   +3 more
doaj   +1 more source

Lentinan -triggered butyrate-producing bacteria drive the expulsion of the intestinal helminth Trichinella spiralis in mice

open access: yesFrontiers in Immunology, 2022
Trichinellosis caused by Trichinella spiralis is a serious zoonosis with a worldwide distribution. Lentinan (LNT) is known to modulate the intestinal environment with noted health benefits, yet the effect of LNT against intestinal helminth is unknown. In
Xuemin Jin   +6 more
doaj   +1 more source

Inhibitory effect of pentoxifylline on the synthesis and deposition of glycosaminoglycans in hypothyroid skin

open access: yesBiotechnology & Biotechnological Equipment, 2022
The skin manifestations in hypothyroidism are common but their advanced forms do not have adequate therapy. Along with achievement of euthyroidism, thyroid-associated dermatopathy (TAD) needs an inhibition of the proliferation and activation of ...
Georgeta Bocheva   +5 more
doaj   +1 more source

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