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Comparison of the transmembrane mucins MUC1 and MUC16 in epithelial barrier function. [PDF]
PLoS ONE, 2014 Membrane-anchored mucins are present in the apical surface glycocalyx of mucosal epithelial cells, each mucosal epithelium having at least two of the mucins.
Ilene K Gipson +3 more
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Microbial binding module employs sophisticated clustered saccharide patches to selectively adhere to mucins [PDF]
Nature CommunicationsThe mucus lining wet body surfaces forms the interphase and barrier for the microbiota and resident microbiomes. Large mucin proteins densely decorated with O-glycans make up the mucus lining to entrap, feed and shape the microbiota, and repress biofilm ...
Thapakorn Jaroentomeechai +22 more
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Frontiers in Immunology, 2020 Throughout the gastrointestinal (GI) tract, a distinct mucus layer composed of highly glycosylated proteins called mucins plays an essential role in providing lubrication for the passage of food, participating in cell signaling pathways and protecting ...
Yun Han Kwon, Waliul I Khan
exaly +3 more sources
Annals of Dermatology, 2018 Mucinous nevus is an uncommon entity classified as either a cutaneous mucinosis or a connective tissue nevus. The condition presents as grouped papules and coalescent plaques growing in a unilateral or zosteriform manner. The key histopathological feature is a band-like deposition of mucin in the superficial dermis.
Min Young Lee +3 more
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Human gastric mucins differently regulate Helicobacter pylori proliferation, gene expression and interactions with host cells. [PDF]
PLoS ONE, 2012 Helicobacter pylori colonizes the mucus niche of the gastric mucosa and is a risk factor for gastritis, ulcers and cancer. The main components of the mucus layer are heavily glycosylated mucins, to which H. pylori can adhere.
Emma C Skoog +5 more
doaj +1 more source
Assay for Assessing Mucin Binding to Bacteria and Bacterial Proteins
Bio-Protocol, 2021 Legionella pneumophila, a Gram-negative bacterium and the causative agent of Legionnaires’ disease, exports over 300 effector proteins/virulence factors, through its type II (T2SS) and type IV secretion systems (T4SS).
Lubov Grigoryeva +4 more
doaj +1 more source
Role of Anthocyanins in the Interaction between Salivary Mucins and Wine Astringent Compounds
Foods, 2023 Wine astringency is a very complex sensation whose complete mechanism has not been entirely described. Not only salivary proline-rich proteins (PRPs) are involved in its development; salivary mucins can also play an important role.
Bárbara Torres-Rochera +3 more
doaj +1 more source
PLoS Neglected Tropical Diseases, 2022 Host cell invasion is a critical step for infection by Trypanosoma cruzi, the agent of Chagas disease. In natural infection, T. cruzi metacyclic trypomastigote (MT) forms establish the first interaction with host cells.
Thiago Souza Onofre +4 more
doaj +2 more sources
Evaluation of the application of enemas containing sucralfate in tissue content of neutral and acid mucins in experimental model of diversion colitis [PDF]
Acta Cirúrgica Brasileira, 2014 PURPOSE:To evaluate the effects of sucralfate on tissue content of neutral and acids mucins in rats with diversion colitis.METHODS: Thirty-six rats were submitted to a proximal right colostomy and a distal mucous fistula.
Felipe Mendonça Chaim +6 more
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Histochemical Assessment of Mucin-Secreting Cells from the Gastric Mucosa of Guinea Pigs
Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca: Veterinary Medicine, 2020 Stomach fragments from 3 guinea pigs were collected from the three regions: cardiac, fundic and pyloric, for histochemical investigations. The anatomical segments were processed by the classical method of inclusion in paraffin and the histological ...
Adriana CHENDE +6 more
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