Results 21 to 30 of about 53,284 (299)

Gp35/50 mucin molecules of Trypanosoma cruzi metacyclic forms that mediate host cell invasion interact with annexin A2.

open access: yesPLoS Neglected Tropical Diseases, 2022
Host cell invasion is a critical step for infection by Trypanosoma cruzi, the agent of Chagas disease. In natural infection, T. cruzi metacyclic trypomastigote (MT) forms establish the first interaction with host cells.
Thiago Souza Onofre   +4 more
doaj   +2 more sources

Cryosectioning the intestinal crypt-villus axis: An ex vivo method to study the dynamics of epigenetic modifications from stem cells to differentiated cells

open access: yesStem Cell Research, 2015
The intestinal epithelium is a particularly attractive biological adult model to study epigenetic mechanisms driving adult stem cell renewal and cell differentiation.
Audrey Vincent   +5 more
doaj   +1 more source

Histochemical Assessment of Mucin-Secreting Cells from the Gastric Mucosa of Guinea Pigs

open access: yesBulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca: Veterinary Medicine, 2020
Stomach fragments from 3 guinea pigs were collected from the three regions: cardiac, fundic and pyloric, for histochemical investigations. The anatomical segments were processed by the classical method of inclusion in paraffin and the histological ...
Adriana CHENDE   +6 more
doaj   +1 more source

Helicobacter suis infection alters glycosylation and decreases the pathogen growth inhibiting effect and binding avidity of gastric mucins [PDF]

open access: yes, 2019
Helicobacter suis is the most prevalent non-Helicobacter pylori Helicobacter species in the human stomach and is associated with chronic gastritis, peptic ulcer disease, and gastric mucosa-associated lymphoid tissue (MALT) lymphoma. H. suis colonizes the
Adamczyk, Barbara   +11 more
core   +1 more source

Integrative analysis of the cancer genome atlas and cancer cell lines encyclopedia large-scale genomic databases: MUC4/MUC16/MUC20 signature is associated with poor survival in human carcinomas

open access: yesJournal of Translational Medicine, 2018
Background MUC4 is a membrane-bound mucin that promotes carcinogenetic progression and is often proposed as a promising biomarker for various carcinomas.
Nicolas Jonckheere   +1 more
doaj   +1 more source

Sialic Acid Glycobiology Unveils Trypanosoma cruzi Trypomastigote Membrane Physiology. [PDF]

open access: yes, 2016
Trypanosoma cruzi, the flagellate protozoan agent of Chagas disease or American trypanosomiasis, is unable to synthesize sialic acids de novo. Mucins and trans-sialidase (TS) are substrate and enzyme, respectively, of the glycobiological system that ...
A Acosta-Serrano   +83 more
core   +5 more sources

A potential role for Drosophila mucins in development and physiology. [PDF]

open access: yesPLoS ONE, 2008
Vital vertebrate organs are protected from the external environment by a barrier that to a large extent consists of mucins. These proteins are characterized by poorly conserved repeated sequences that are rich in prolines and potentially glycosylated ...
Zulfeqhar A Syed   +3 more
doaj   +1 more source

Role of sialic acid in brachyspira hyodysenteriae adhesion to pig colonic mucins [PDF]

open access: yes, 2019
Infection with Brachyspira hyodysenteriae results in mucoid hemorrhagic diarrhea. This pathogen is associated with the colonic mucus layer, mainly composed of mucins. Infection regulates mucin O-glycosylation in the colon and increases mucin secretion as
Haesebrouck, Freddy   +3 more
core   +2 more sources

Lamellar Structures of MUC2-Rich Mucin: A Potential Role in Governing the Barrier and Lubricating Functions of Intestinal Mucus [PDF]

open access: yes, 2012
Mucus is a ubiquitous feature of mammalian wet epithelial surfaces, where it lubricates and forms a selective barrier that excludes a range of particulates, including pathogens, while hosting a diverse commensal microflora.
Garcia De La Torre, Angela   +6 more
core   +1 more source

The study of mucin histochemistry in benign and malignant lesions of prostate

open access: yesJournal of the Scientific Society, 2014
Objective: To evaluate the usefulness of mucin stains in differentiating benign and malignant lesions of prostate. Materials and Methods: Sections were obtained from archival paraffin blocks which included randomly selected 70 cases of benign hyperplasia
Durgaprasad N Agrawal   +3 more
doaj   +1 more source

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