Results 21 to 30 of about 29,521 (261)

Cryosectioning the intestinal crypt-villus axis: An ex vivo method to study the dynamics of epigenetic modifications from stem cells to differentiated cells

open access: yesStem Cell Research, 2015
The intestinal epithelium is a particularly attractive biological adult model to study epigenetic mechanisms driving adult stem cell renewal and cell differentiation.
Audrey Vincent   +5 more
doaj   +1 more source

Histochemical Assessment of Mucin-Secreting Cells from the Gastric Mucosa of Guinea Pigs

open access: yesBulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca: Veterinary Medicine, 2020
Stomach fragments from 3 guinea pigs were collected from the three regions: cardiac, fundic and pyloric, for histochemical investigations. The anatomical segments were processed by the classical method of inclusion in paraffin and the histological ...
Adriana CHENDE   +6 more
doaj   +1 more source

Integrative analysis of the cancer genome atlas and cancer cell lines encyclopedia large-scale genomic databases: MUC4/MUC16/MUC20 signature is associated with poor survival in human carcinomas

open access: yesJournal of Translational Medicine, 2018
Background MUC4 is a membrane-bound mucin that promotes carcinogenetic progression and is often proposed as a promising biomarker for various carcinomas.
Nicolas Jonckheere   +1 more
doaj   +1 more source

A potential role for Drosophila mucins in development and physiology. [PDF]

open access: yesPLoS ONE, 2008
Vital vertebrate organs are protected from the external environment by a barrier that to a large extent consists of mucins. These proteins are characterized by poorly conserved repeated sequences that are rich in prolines and potentially glycosylated ...
Zulfeqhar A Syed   +3 more
doaj   +1 more source

The study of mucin histochemistry in benign and malignant lesions of prostate

open access: yesJournal of the Scientific Society, 2014
Objective: To evaluate the usefulness of mucin stains in differentiating benign and malignant lesions of prostate. Materials and Methods: Sections were obtained from archival paraffin blocks which included randomly selected 70 cases of benign hyperplasia
Durgaprasad N Agrawal   +3 more
doaj   +1 more source

Enemas with mesalazine increase the tissue contents of mucins in the colonic mucosa devoid of fecal stream [PDF]

open access: yesActa Cirúrgica Brasileira, 2019
Purpose: To evaluate the inflammatory reaction and measure the content of mucins, in the colonic mucosa without fecal stream submit to intervention with mesalazine.
Carlos Augusto Real Martinez   +6 more
doaj   +2 more sources

Mucins and the Microbiome [PDF]

open access: yesAnnual Review of Biochemistry, 2020
Generating the barriers that protect our inner surfaces from bacteria and other challenges requires large glycoproteins called mucins. These come in two types, gel-forming and transmembrane, all characterized by large, highly O -glycosylated mucin domains that are diversely decorated by Golgi
openaire   +2 more sources

An inventory of mucin genes in the chicken genome shows that the mucin domain of Muc13 is encoded by multiple exons and that ovomucin is part of a locus of related gel-forming mucins

open access: yesBMC Genomics, 2006
Background Mucins are large glycoproteins that cover epithelial surfaces of the body. All mucins contain at least one PTS domain, a region rich in proline, threonine and serine.
Hansson Gunnar C   +2 more
doaj   +1 more source

Flagellin is essential for initial attachment to mucosal surfaces by Clostridioides difficile

open access: yesMicrobiology Spectrum, 2023
Mucins are glycoproteins which can be found in host cell membranes and as a gelatinous surface formed from secreted mucins. Mucosal surfaces in mammals form a barrier to invasive microbes, particularly bacteria, but are a point of attachment for others ...
Ben Sidner   +8 more
doaj   +1 more source

Mucins and Pathogenic Mucin-Like Molecules Are Immunomodulators During Infection and Targets for Diagnostics and Vaccines

open access: yesFrontiers in Chemistry, 2019
Mucins and mucin-like molecules are highly O-glycosylated proteins present on the cell surface of mammals and other organisms. These glycoproteins are highly diverse in the apoprotein and glycan cores and play a central role in many biological processes ...
Sandra Pinzón Martín   +5 more
doaj   +1 more source

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