Results 41 to 50 of about 37,093 (292)

The protective role of conjunctival goblet cell mucin sialylation

open access: yesNature Communications, 2023
Conjunctival goblet cells secrete mucins that are heavily glycosylated. Here, the authors show that sialylation of mucins is essential for capturing and encapsulates allergen particles and thus reduces the risk for developing allergic conjunctivitis.
Moe Matsuzawa   +19 more
doaj   +1 more source

Aeromonas salmonicida binds α2-6 linked sialic acid, which is absent among the glycosphingolipid repertoires from skin, gill, stomach, pyloric caecum, and intestine

open access: yesVirulence, 2022
Carbohydrates can both protect against infection and act as targets promoting infection. Mucins are major components of the slimy mucus layer covering the fish epithelia.
John Benktander   +4 more
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Upregulation of cell-surface mucin MUC15 in human nasal epithelial cells upon influenza A virus infection

open access: yesBMC Infectious Diseases, 2019
Background Cell-surface mucins are expressed in apical epithelial cells of the respiratory tract, and contribute a crucial part of the innate immune system.
Zhuang Gui Chen   +9 more
doaj   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

open access: yesFEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki   +5 more
wiley   +1 more source

A detection and quantification label-free tool to speed up downstream processing of model mucins. [PDF]

open access: yesPLoS ONE, 2018
Mucins are high-molecular weight glycoproteins (0.25-20 MDa) containing one or more domains that are heavily O-glycosylated. Their implications as targets for cancer treatment have increased the interest in these glycoproteins, mainly in the fields of ...
Sofia B Carvalho   +7 more
doaj   +1 more source

Advances in Sustainable and Wearable Textile Based Soft Robotics

open access: yesAdvanced Functional Materials, EarlyView.
This Review examines advances in wearable textile‐based soft robotics, focusing on sustainable materials, integrated sensing, and scalable actuation. It discusses manufacturing and system integration across healthcare, assistive robotics, prosthetics, and human–machine interfaces, and highlights key challenges in circular design, including life‐cycle ...
Zahir Abbas   +6 more
wiley   +1 more source

The role of human breast milk mucus and mucins in HIV-AIDS [PDF]

open access: yes, 2012
Includes abstract.Includes bibliographical references.Milk molecules such as mucins, antibodies, bactericidal enzymes like lysozymes and fatty acids that lyse bacteria, viral particles and bacterial peptides, offer anti-microbial activity in milk ...
Mthembu, Yolanda
core   +1 more source

Transmembrane mucins in lung adenocarcinoma: understanding of current molecular mechanisms and clinical applications

open access: yesCell Death Discovery
The mucin family is a group of highly glycosylated macromolecules widely present in human epithelial cells and with subtypes of secreted and membrane-associated forms.
Xiaoqing Li   +8 more
doaj   +1 more source

Analysis of stromal mucin in oral epithelial dysplasia & oral squamous cell carcinoma- A histochemical study

open access: yesJournal of Oral Biology and Craniofacial Research, 2019
Background: Mucins are glycoproteins that act as a selective molecular barrier and its alterations usually accompany the carcinogenesis. Aim: To evaluate the transition of mucins in the grades of oral epithelial dysplasia (OED) and oral squamous cell ...
Ankita Sahni   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy