Is the colon mucosa affected by ten days of gastric restriction in an animal model? [PDF]
Acta Cirúrgica Brasileira, 2019 Purpose To identify whether the colon mucosa is affected by ten days of gastric restriction in an animal model. Methods An experimental model of gastric restriction was devised using rats.
Flávia Emi Akamatsu +10 more
doaj +1 more source
The biochemical characterisation of respiratory mucus & mucins in normal, asthma & COPD [PDF]
, 2009 Includes abstract.Includes bibliographical references (leaves 78-87).Airway mucus hyper-secretion is the main cause of mortality and morbidity in respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD) and is the leading ...
Trimmel, Astrid Joan
core +1 more source
Mucins as diagnostic and prognostic biomarkers in a fish-parasite model: transcriptional and functional analysis. [PDF]
PLoS ONE, 2013 Mucins are O-glycosylated glycoproteins present on the apex of all wet-surfaced epithelia with a well-defined expression pattern, which is disrupted in response to a wide range of injuries or challenges.
Jaume Pérez-Sánchez +5 more
doaj +1 more source
PLoS ONE, 2019 Disease outbreaks are limiting factors for an ethical and economically sustainable aquaculture industry. The first point of contact between a pathogen and a host occurs in the mucus, which covers the epithelial surfaces of the skin, gills and ...
János Tamás Padra +6 more
doaj +1 more source
The inhibition of HIV-1 activity by crude mucus and purified mucin (mucous glycoproteins) from saliva, breast milk and the cervical tract of normal subjects, HIV positive individuals and patients with HIV-AIDS [PDF]
, 2007 Includes bibliographical references (leaves 140-161).Human saliva, breast milk and cervical secretions contain several non-immunological components including mucins (mucous glycoproteins), which protect the gastrointesinal and female reproductive tracts ...
Habte, Habtom Haileselassie
core +1 more source
Genome wide analysis of the bovine mucin genes and their gastrointestinal transcription profile
BMC Genomics, 2011 Background Mucins are large glycoproteins implicated in protection of all mucosal surfaces. In humans and rodents, the mucin gene family has been well described and previous studies have investigated the distribution and function of mucins in the ...
Vercruysse Jozef +6 more
doaj +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Airway Mucins Inhibit Oxidative and Non-Oxidative Bacterial Killing by Human Neutrophils
Frontiers in Pharmacology, 2020 Neutrophil killing of bacteria is mediated by oxidative and non-oxidative mechanisms. Oxidants are generated through the NADPH oxidase complex, whereas antimicrobial proteins and peptides rank amongst non-oxidative host defenses.
André M. Cantin +3 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
State Functions in Latvia Through an Institutional Prism: The Constitution as a Pedestal
Baltic Journal of Law & PoliticsThe article offers a conceptual perspective on the relevance of the theory of state organs developed in the 19th century in Germany for contemporary state theory in Latvia.
Šulmane Dace, Muciņš Linards
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