Stem Cell Research, 2015 The intestinal epithelium is a particularly attractive biological adult model to study epigenetic mechanisms driving adult stem cell renewal and cell differentiation.
Audrey Vincent +5 more
doaj +1 more source
Role of sialic acid in brachyspira hyodysenteriae adhesion to pig colonic mucins [PDF]
, 2019 Infection with Brachyspira hyodysenteriae results in mucoid hemorrhagic diarrhea. This pathogen is associated with the colonic mucus layer, mainly composed of mucins. Infection regulates mucin O-glycosylation in the colon and increases mucin secretion as
Haesebrouck, Freddy +3 more
core +2 more sources
Journal of Translational Medicine, 2018 Background MUC4 is a membrane-bound mucin that promotes carcinogenetic progression and is often proposed as a promising biomarker for various carcinomas.
Nicolas Jonckheere +1 more
doaj +1 more source
Mucosubstances in the porcine gastrointestinal tract: Fixation, staining and quantification [PDF]
, 2019 Mucins are of great interest in intestinal research and histochemical methods are often employed to identify them. Since it is in the nature of mucins that they are “hard to hold onto” once they come into contact with water, a frequently used medium in ...
Drewes, Barbara +3 more
core +1 more source
A potential role for Drosophila mucins in development and physiology. [PDF]
PLoS ONE, 2008 Vital vertebrate organs are protected from the external environment by a barrier that to a large extent consists of mucins. These proteins are characterized by poorly conserved repeated sequences that are rich in prolines and potentially glycosylated ...
Zulfeqhar A Syed +3 more
doaj +1 more source
Mucin glycosylation and sulphation in airway epithelial cells is not influenced by cystic fibrosis transmembrane conductance regulator expression [PDF]
, 2005 Abnormalities in mucus properties and clearance make a major contribution to the pathology of cystic fibrosis (CF). Our aim was to test the hypothesis that the defects in CF mucus are a direct result of mutations in the CF transmembrane conductance ...
Dell, Anne +6 more
core +1 more source
Dynamic interactions of a conserved enterotoxigenic Escherichia coli adhesin with intestinal mucins govern epithelium engagement and toxin delivery [PDF]
, 2016 At present, there is no vaccine for enterotoxigenic Escherichia coli (ETEC), an important cause of diarrheal illness. Nevertheless, recent microbial pathogenesis studies have identified a number of molecules produced by ETEC that contribute to its ...
Bhullar, Kirandeep +7 more
core +2 more sources
Effect of native gastric mucus on in vivo hybridization therapies directed at Helicobacter pylori [PDF]
, 2015 Helicobacter pylori infects more than 50% of the worldwide population. It is mostly found deep in the gastric mucus lining of the stomach, being a major cause of peptic ulcers and gastric adenocarcinoma. To face the increasing resistance of H.
Azevedo, Nuno F +13 more
core +6 more sources
The study of mucin histochemistry in benign and malignant lesions of prostate
Journal of the Scientific Society, 2014 Objective: To evaluate the usefulness of mucin stains in differentiating benign and malignant lesions of prostate. Materials and Methods: Sections were obtained from archival paraffin blocks which included randomly selected 70 cases of benign hyperplasia
Durgaprasad N Agrawal +3 more
doaj +1 more source
Enemas with mesalazine increase the tissue contents of mucins in the colonic mucosa devoid of fecal stream [PDF]
Acta Cirúrgica Brasileira, 2019 Purpose: To evaluate the inflammatory reaction and measure the content of mucins, in the colonic mucosa without fecal stream submit to intervention with mesalazine.
Carlos Augusto Real Martinez +6 more
doaj +2 more sources