A bulky glycocalyx fosters metastasis formation by promoting G1 cell cycle progression. [PDF]
, 2017 Metastasis depends upon cancer cell growth and survival within the metastatic niche. Tumors which remodel their glycocalyces, by overexpressing bulky glycoproteins like mucins, exhibit a higher predisposition to metastasize, but the role of mucins in ...
Barnes, J Matthew +7 more
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Urachal Mucinous Cystadenocarcinoma [PDF]
BMJ Case Reports, 2019 A 57-year-old man presented with a 6-month history of pelvic fullness. He had no lower urinary tract symptoms or altered bowel habits. On examination, there was a non-tender pelvic mass which extended from the pubic symphysis to the level of the umbilicus.
Ryan Pereira +3 more
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Drop spreading and drifting on a spatially heterogeneous film: capturing variability with asymptotics and emulation [PDF]
, 2018 A liquid drop spreading over a thin heterogeneous precursor film (such as an inhaled droplet on the mucus-lined wall of a lung airway) will experience perturbations in shape and location as its advancing contact line encounters regions of low or high ...
Coveney, Sam +2 more
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Perianal mucinous adenocarcinoma [PDF]
Cancer, 1977 Perianal mucinous adenocarcinoma, also known as anal duct or anal gland carcinoma, is a rare tumor usually associated with chronic fistulae-in-ano. Whether the tumor occurs primarily and the fistula is a secondary manifestation, or whether this tumor arises in a chronic fistulous tract is debatable. Diagnosis can be made only by open deep biopsy of the
P G, Prioleau, M S, Allen, T, Roberts
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Lamellar Structures of MUC2-Rich Mucin: A Potential Role in Governing the Barrier and Lubricating Functions of Intestinal Mucus [PDF]
, 2012 Mucus is a ubiquitous feature of mammalian wet epithelial surfaces, where it lubricates and forms a selective barrier that excludes a range of particulates, including pathogens, while hosting a diverse commensal microflora.
Garcia De La Torre, Angela +6 more
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A mucin-like peptide from Fasciola hepatica instructs dendritic cells with parasite specific Th1-polarizing activity [PDF]
, 2017 Fasciolosis is a trematode zoonosis of interest in public health and cattle production. We report here the immunostimulatory effect of a 66 mer mucin-like peptide from Fasciola hepatica (Fhmuc), which synergizes with lipopolysaccharide (LPS) to promote ...
Brossard, Natalie +6 more
core +1 more source
Receptor uptake arrays for vitamin B12, siderophores and glycans shape bacterial communities
, 2017 Molecular variants of vitamin B12, siderophores and glycans occur. To take up variant forms, bacteria may express an array of receptors. The gut microbe Bacteroides thetaiotaomicron has three different receptors to take up variants of vitamin B12 and 88 ...
Frank, Steven A.
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Retroperitoneal mucinous cystadenoma
European Journal of Obstetrics & Gynecology and Reproductive Biology, 1999 A case of retroperitoneal mucinous cystadenoma histologically confirmed in a 21-year-old woman is reported. Although ultrasound, CT and MR detected the tumor, a preoperative diagnosis could not be established by imaging methods. The cystic tumor was removed and microscopic examination revealed a mucinous cystadenoma. Mullerian mesothelial metaplasia of
Kehagias, DT +3 more
openaire +4 more sources
Unraveling the Differences of the Hydrolytic Activity of Trypanosoma cruzi trans-Sialidase and Trypanosoma rangeli Sialidase: A Quantum Mechanics–Molecular Mechanics Modeling Study [PDF]
, 2014 Chagas’ disease, also known as American trypanosomiasis, is a lethal, chronic disease that currently affects more than 10 million people in Central and South America. The trans-sialidase from Trypanosoma cruzi (T. cruzi, TcTS) is a crucial enzyme for the
Bueren Calabuig, Juan A. +2 more
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Model Systems of Human Intestinal Flora, to Set Acceptable Daily Intakes of Antimicrobial Residues [PDF]
, 2000 The veterinary use of antimicrobial drugs in food producing animals may result in residues in food, that might modify the consumer gut flora. This review compares three model systems that maintain a complex flora of human origin: (i) human flora ...
Cemiglia CE +9 more
core +2 more sources