Results 71 to 80 of about 53,284 (299)

Transmembrane mucins in lung adenocarcinoma: understanding of current molecular mechanisms and clinical applications

open access: yesCell Death Discovery
The mucin family is a group of highly glycosylated macromolecules widely present in human epithelial cells and with subtypes of secreted and membrane-associated forms.
Xiaoqing Li   +8 more
doaj   +1 more source

Mucosubstances in the porcine gastrointestinal tract: Fixation, staining and quantification [PDF]

open access: yes, 2019
Mucins are of great interest in intestinal research and histochemical methods are often employed to identify them. Since it is in the nature of mucins that they are “hard to hold onto” once they come into contact with water, a frequently used medium in ...
Drewes, Barbara   +3 more
core   +1 more source

Evaluating the capacity of human gut microorganisms to colonize the zebrafish larvae (Danio rerio) [PDF]

open access: yes, 2018
Indexación: Scopus.In this study we evaluated if zebrafish larvae can be colonized by human gut microorganisms. We tested two strategies: (1) through transplantation of a human fecal microbiota and (2) by successively transplanting aerotolerant anaerobic
Angelica Reyes-Jara   +14 more
core   +4 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Dynamic interactions of a conserved enterotoxigenic Escherichia coli adhesin with intestinal mucins govern epithelium engagement and toxin delivery [PDF]

open access: yes, 2016
At present, there is no vaccine for enterotoxigenic Escherichia coli (ETEC), an important cause of diarrheal illness. Nevertheless, recent microbial pathogenesis studies have identified a number of molecules produced by ETEC that contribute to its ...
Bhullar, Kirandeep   +7 more
core   +2 more sources

Drop spreading with random viscosity [PDF]

open access: yes, 2016
We examine theoretically the spreading of a viscous liquid drop over a thin film of uniform thickness, assuming the liquid's viscosity is regulated by the concentration of a solute that is carried passively by the spreading flow. The solute is assumed to
Jensen, Oliver E., Xu, Feng
core   +9 more sources

Analysis of stromal mucin in oral epithelial dysplasia & oral squamous cell carcinoma- A histochemical study

open access: yesJournal of Oral Biology and Craniofacial Research, 2019
Background: Mucins are glycoproteins that act as a selective molecular barrier and its alterations usually accompany the carcinogenesis. Aim: To evaluate the transition of mucins in the grades of oral epithelial dysplasia (OED) and oral squamous cell ...
Ankita Sahni   +5 more
doaj   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

open access: yesAdvanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz   +3 more
wiley   +1 more source

Bovine Submaxillary Mucin [PDF]

open access: yesNature, 1961
A CONVENIENT method for the isolation of bovine submaxillary mucin in a relatively undegraded and homogeneous state compared to earlier methods1 has been developed in this Laboratory. Fresh glands (640 gm.) were ground and stirred mechanically with three changes of 500 ml. of cold water for a total of 54 hr.
S, TSUIKI, Y, HASHIMOTO, W, PIGMAN
openaire   +2 more sources

Gut microbiota facilitates dietary heme-induced epithelial hyperproliferation by opening the mucus barrier in colon [PDF]

open access: yes, 2015
Colorectal cancer risk is associated with diets high in red meat. Heme, the pigment of red meat, induces cytotoxicity of colonic contents and elicits epithelial damage and compensatory hyperproliferation, leading to hyperplasia.
Clara Belzer   +13 more
core   +2 more sources

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