Cubic Microcontainers Improve In Situ Colonic Mucoadhesion and Absorption of Amoxicillin in Rats [PDF]
Pharmaceutics, 2020 An increased interest in colonic drug delivery has led to a higher focus on the design of delivery devices targeting this part of the gastrointestinal tract. Microcontainers have previously facilitated an increase in oral bioavailability of drugs.
Juliane Fjelrad Christfort +7 more
doaj +2 more sources
Development of a Standardized Method for Measuring Bioadhesion and Mucoadhesion That Is Applicable to Various Pharmaceutical Dosage Forms [PDF]
Pharmaceutics, 2022 Although some methods for measuring bioadhesion/mucoadhesion have been proposed, a standardized method is not yet available. This is expected to hinder systematic comparisons of results across studies.
Lola Amorós-Galicia +7 more
doaj +2 more sources
Development of keratin nanoparticles for controlled gastric mucoadhesion and drug release [PDF]
Journal of Nanobiotechnology, 2018 Background Nanotechnology-based drug delivery systems have been widely used for oral and systemic dosage forms delivery depending on the mucoadhesive interaction, and keratin has been applied for biomedical applications and drug delivery.
Zhongjun Cheng +8 more
doaj +2 more sources
Tobramycin-loaded nanoparticles of thiolated chitosan for ocular drug delivery: Preparation, mucoadhesion and pharmacokinetic evaluation [PDF]
Heliyon, 2023 The present work aimed to develop nanoparticles of tobramycin (TRM) using thiolated chitosan (TCS) in order to improve the mucoadhesion, antibacterial effect and pharmacokinetics.
Sadaf Javed +14 more
doaj +2 more sources
Colloidal Interactions in Simulated Intestinal Fluids: Implications for Oral Drug Delivery at the Nanoscale [PDF]
Small ScienceOral drug delivery remains the most preferred administration route, and new oral delivery concepts continuously arise to enable oral delivery of new therapeutics. This study investigates how colloidal structures in five simulated intestinal fluids (SIFs)
Juliane Fjelrad Christfort +5 more
doaj +2 more sources
Recent advancement in polymeric nanoparticles for oral chemotherapy: Transforming cancer treatment [PDF]
BioImpactsOral chemotherapy offers an attractive alternative to conventional intravenous administration by providing high patient compliance and improved treatment adherence.
Karthik Mangu +2 more
doaj +2 more sources
Impact of variables on buccal mucoadhesive film-forming spray for clotrimazole [PDF]
Journal of Advanced Pharmaceutical Technology & ResearchBuccal spray is an attractive dosage form for its ease of application, especially for infant and geriatric patients. The aim in this work was to optimize and prepare a clotrimazole buccal spray through exploring the role of main variables producing a ...
Nidhal Khazaal Maraie +1 more
doaj +2 more sources
Sodium Carboxymethyl Cellulose-Stabilised Multiple Emulsions with pH-Sensitive Behaviour, Enhanced Stability and Mucoadhesion for Oral Delivery of Chemopreventive Agents. [PDF]
PharmaceuticsMarkowska-Radomska A +2 more
europepmc +3 more sources
Mitigating Mucoadhesion of β-Cyclodextrins via PEGylation: Insights from <sup>19</sup>F Diffusion NMR Analysis. [PDF]
Int J Mol SciNguyen KTH, Ba Y.
europepmc +3 more sources
Heat-Induced Structural Changes in Lactoferrin for Enhanced Mucoadhesion. [PDF]
ACS Appl Bio MaterHazt B +6 more
europepmc +2 more sources