Formulation and evaluation of floating mucoadhesive alginate beads for targetingHelicobacter pylori [PDF]
Objectives: There are various obstacles in the eradication of Helicobacter.pylori (H. pylori) infections, including low antibiotic levels and poor accessibility of the drug at the site of the infection.
Adebisi +59 more
core +1 more source
Polycomplex Carrier for Buccal Mucoadhesion Delivery of Metronidazole
Introduction. One of the well-known requirements for buccal drug delivery systems is the demonstration of mucoadhesive properties of the carrier, ensuring retention on the mucosa for a long time with the gradual release of the included drug. It should be
R. I. Moustafine +4 more
doaj +1 more source
Polysaccharide food matrices for controlling the release, retention and perception of flavours [PDF]
Polysaccharides have many roles across both the food and pharmaceutics industries. They are commonly used to enhance viscosity, stabilise emulsions and to add bulk to food products.
Cook, Sarah L. +3 more
core +1 more source
The buccal route of administration has many advantages, including gastrointestinal bypass surgery and first pass through the liver. The mucoadhesive membrane is a retention dosage form that can release the drug directly into the biological matrix. Cheek technology has proven to be an advanced alternative to other traditional devices.
SINDHU G. D. +2 more
openaire +2 more sources
A Thermosensitive Gel Containing Biodegradable Nanoparticles Carrying Calcium Hydroxide as Antibacterial Intracanal Therapy. [PDF]
ABSTRACT Aim To characterise and evaluate mucoadhesive strength and antibacterial properties of a nanotechnological formulation for endodontic disinfection based on biodegradable nanoparticles dispersed in a thermosensitive gel containing calcium hydroxide (Ca(OH)2‐NPs‐gel).
Roig-Soriano X +9 more
europepmc +2 more sources
Freeze-dried mucoadhesive polymeric system containing pegylated lipoplexes : towards a vaginal sustained released system for siRNA [PDF]
peer reviewedTopical vaginal sustained delivery of siRNA presents a significant challenge due to the short residence time of formulations. Therefore, a drug delivery system capable to adhere to the vaginal mucosa is desirable, as it could allow a ...
Furst, Tania +7 more
core +1 more source
The formation of mucosal ulcers is an end result of epithelial damage, and it occurs due to some specific causes, such as trauma, aphthous stomatitis, lichen planus and lichenoid reactions, cytotoxic effects of chemotherapy and radiation, and drug ...
Thais F. R. Alves +9 more
doaj +1 more source
Mucoadhesive drug delivery systems are those that provide intimate contact of the drug with the mucosa for an extended period of time. In present work, mucoadhesive chitosan microspheres of Levosalbutamol sulphate were prepared by Spray drying method ...
D Dinal Patel +3 more
doaj +1 more source
Chitosan-g-oligo(epsilon-caprolactone) polymeric micelles: microwave-assisted synthesis and physicochemical and cytocompatibility characterization [PDF]
With the aim to produce mucoadhesive polymeric micelles for drug administration by mucosal routes, chitosan-g-oligo(epsilon-caprolactone) copolymers were synthesized by the microwave-assisted ring-opening polymerization of epsilon-caprolactone using ...
Calderon, Marcelo +5 more
core +1 more source
Development of Mucoadhesive Gel Microbicide to Target Mucosal HIV Reservoirs [PDF]
The wide use of microbicide is mainly depends on its effectiveness, less frequent application, ready availability and most importantly cost. The aim of this work was to develop affordable microbicide mucoadhesive gel formulation of synthetic anti HIV ...
Shegokar, Ranjita, Singh, Kamalinder K
core +1 more source

