Results 41 to 50 of about 9,290 (251)
Mucoadhesion: mucin-polymer molecular interactions
International Journal of Pharmaceutics, 2021 Mucoadhesion, adhesion of a material to a mucous membrane or a mucus-covered surface, has been employed in drug delivery to prolong contact with adsorption sites and consequently a likely improvement of drug absorption. Mucoadhesion in the oral cavity also provides additional effects on tactile mouthfeel and extended flavor delivery, which impact ...
Quoc Dat, Pham +5 more
openaire +2 more sources
Antibiotics, 2021 The emergence of resistance to antifungal drugs has made the treatment of vulvovaginal candidiasis (VVC) very challenging. Among natural substances, biosurfactants (BS) produced by Lactobacillus have gained increasing interest in counteracting Candida ...
Angela Abruzzo +8 more
doaj +1 more source
Functional physico-chemical, ex vivo permeation and cell viability characterization of omeprazole loaded buccal films for pediatric drug delivery [PDF]
, 2016 Buccal films were prepared from aqueous and ethanolic Metolose gels using the solvent casting approach (40 °C). The hydration (PBS and simulated saliva), mucoadhesion, physical stability (20 °C, 40 °C), in vitro drug (omeprazole) dissolution (PBS and ...
Boateng, Joshua +2 more
core +2 more sources
Sorafenib Repurposing for Ophthalmic Delivery by Lipid Nanoparticles: A Preliminary Study
Pharmaceutics, 2021 Uveal melanoma is the second most common melanoma and the most common intraocular malignant tumour of the eye. Among various treatments currently studied, Sorafenib was also proposed as a promising drug, often administered with other compounds in order ...
Angela Bonaccorso +8 more
doaj +1 more source
Novel glycopolymer hydrogels as mucosa-mimetic materials to reduce animal testing [PDF]
, 2015 Glycopolymer hydrogels capable of mimicking mucosal tissue in mucoadhesion testing have been designed. Liquid formulations containing mucoadhesive polymers were found to be retained on these tissues to the same extent as ex vivo gastric mucosa, when ...
Bansil +32 more
core +2 more sources
Posterior Segment Ophthalmic Drug Delivery: Role of Muco-Adhesion with a Special Focus on Chitosan
Pharmaceutics, 2021 Posterior segment eye diseases (PSEDs) including age macular degeneration (AMD) and diabetic retinopathy (DR) are amongst the major causes of irreversible blindness worldwide.
Ayah Mohammad Burhan +8 more
doaj +1 more source
Polysaccharide based formulations for mucosal drug delivery: A review [PDF]
, 2015 There has been increased interest in novel drug delivery systems to be administered via mucosal routes as an alternative to the currently used traditional routes such as parenteral (injections) and oral routes of administration.
Boateng, Joshua +2 more
core +1 more source
Drug Delivery, 2019 Oral drug delivery is an attractive noninvasive alternative to injectables. However, oral delivery of biopharmaceuticals is highly challenging due to low stability during transit in the gastrointestinal tract (GIT), resulting in low systemic ...
Stine Harloff-Helleberg +6 more
doaj +1 more source
Development and evaluation of aceclofenac-loaded mucoadhesive microcapsules
Journal of Advanced Pharmaceutical Technology & Research, 2011 Microencapsulation is an accepted process used to achieve controlled release and drug targeting for many years. Mucoadhesion has been a topic of interest in the design of drug delivery systems to prolong its intestinal residence time.
Santhosh Kumar Mankala +2 more
doaj +1 more source
Dizajniranje i vrednovanje okularnih umetaka moksifloksacin hidroklorida [PDF]
, 2012 The objective of the present investigation was to prepare and evaluate ocular inserts of moxifloxacin. An ocular insert was made from an aqueous dispersion of moxifloxacin, sodium alginate, polyvinyl alcohol, and dibutyl phthalate by the film casting ...
A. Mundada +18 more
core +2 more sources