Results 71 to 80 of about 9,290 (251)

Methods to determine the interactions of micro- and nanoparticles with mucus [PDF]

open access: yes, 2015
The present review provides an overview of methods and techniques for studying interactions of micro- and nanoparticulate drug delivery system with mucus.
Adebisi   +92 more
core   +2 more sources

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

open access: yesBMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen   +7 more
wiley   +1 more source

Design of a nanostructured mucoadhesive system containing curcumin for buccal application: from physicochemical to biological aspects

open access: yesBeilstein Journal of Nanotechnology, 2019
Mucoadhesive nanostructured systems comprising poloxamer 407 and Carbopol 974P® have already demonstrated good mucoadhesion, as well as improved mechanical and rheological properties.
Sabrina Barbosa de Souza Ferreira   +10 more
doaj   +1 more source

Development of a Mucoadhesive and an in Situ Gelling Formulation Based on κ-Carrageenan for Application on Oral Mucosa and Esophagus Walls. II. Loading of a Bioactive Hydroalcoholic Extract

open access: yesMarine Drugs, 2019
The aim of the present work was to load a Hibiscus sabdariffa (HS) hydroalcoholic extract into in situ gelling formulations for the treatment of oral mucositis and esophagitis.
Barbara Vigani   +8 more
doaj   +1 more source

A Mucoadhesive Hydrogel for Precise Resveratrol Delivery in the Management of Inflammatory Bowel Disease

open access: yesFood Frontiers, EarlyView.
CMTR‐Gel targeting to the inflamed mucosa by electrostatic interactions. ABSTRACT Natural drug‐food homology compounds have vast therapeutic potential, particularly for inflammatory bowel disease (IBD), but their poor water solubility, instability, and limited mucosal availability hinder their clinical translation.
Wenqiu Xu   +7 more
wiley   +1 more source

Characteristics, preparation and applicability in oral delivery systems of cellulose ether–based buccal films

open access: yesDrug Delivery
With the rapid development of buccal films (BFs), the demand for film-forming materials and preparation techniques has increased. Cellulose ethers (CEs) exhibit favorable properties, such as effective film formation, mucosal adhesion, and ...
Hong Cheng   +5 more
doaj   +1 more source

New Approach in Ocular Drug Delivery: In vitro and ex vivo Investigation of Cyclodextrin-Containing, Mucoadhesive Eye Drop Formulations

open access: yesDrug Design, Development and Therapy, 2021
Tivadar Bíró,1 Alexandra Bocsik,2 Bisera Jurišić Dukovski,3 Ilona Gróf,2,4 Jasmina Lovrić,3 Ildikó Csóka,1 Mária A Deli,2 Zoltán Aigner1 1Institute of Pharmaceutical Technology and Regulatory ...
Bíró T   +7 more
doaj  

Control of odontogenic pain by diclofenac and meloxicam mucoadhesive patches: A randomized, double-blinded, placebo-controlled, preliminary study

open access: yesJournal of Indian Academy of Oral Medicine and Radiology, 2016
Aims and Objectives: To evaluate and compare the efficacy of diclofenac and meloxicam as mucoadhesive patches in dental pain management. Materials and Method: This study was conducted among 45 adult patients of either sex, who were diagnosed with dental ...
Pratik R Pipalia   +3 more
doaj   +1 more source

Development and Evaluation of Tannic Acid-Coated Nanosuspension for Enhancing Oral Bioavailability of Curcumin

open access: yesPharmaceutics, 2021
Curcumin (CUR) has been used in the treatment of various diseases such as cough, fever, skin disease, and infection because of various biological benefits such as anti-inflammatory, antiviral, antibacterial, and antitumor activity.
Hyeonmin Lee   +6 more
doaj   +1 more source

Mucoadhesive polymers for oral transmucosal drug delivery: a review [PDF]

open access: yes, 2012
he oral mucosa offers an interesting site for the application of dosage forms that release drugs within/throughout the oral mucosa, by assuring a high drug bioavailability for topic and systemic effects.
Bagan, J   +6 more
core   +1 more source

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