Results 61 to 70 of about 1,383,541 (213)

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

A novel lidocaine hydrochloride mucoadhesive films for periodontal diseases

Journal of Materials Science: Materials in Medicine, 2019
Periodontal diseases are inflammatory disorders caused primarily by dental plaque microorganisms that even may need surgery to remove damaged tissue. Adhesive biocompatible films may be an adequate form in order to improve drug retention or prevent microbial infections by covering the surgical site.
María Pleguezuelos-Villa, Amparo Nácher, María Jesús Hernández, M. A. Ofelia Vila Busó, María Barrachina, Nuria Peñalver, Octavio Díez-Sales   +6 more
openaire   +3 more sources

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). II. Treatments in more advanced clinical development

Epilepsia, EarlyView.
Abstract This article summarizes data for 13 investigational treatments for which at least preliminary seizure outcome data in patients with epilepsy were reported at the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices held in Madrid, Spain, on May 3–6, 2026.
Meir Bialer, Cecilie Johannessen Landmark, Matthias J. Koepp, Emilio Perucca, Piero Perucca, Torbjörn Tomson, H. Steve White, Elaine Wirrell   +7 more
wiley   +1 more source

Peptide‐based antibacterial nanoplatforms: Design principles, stimuli‐regulated behaviors, and applications

Responsive Materials, EarlyView.
Peptide‐based antibacterial nanoplatforms, encompassing self‐assembled peptides and peptide‐engineered inorganic, polymeric, and lipid nanocarriers, are systematically reviewed. The article highlights design principles and stimuli‐responsive regulation for improving peptide stability, delivery efficiency, and antibacterial performance.
Peng Tan, Chenlong Zhou, Shuaikang Yang, Zhenduo Chen, Guanghui Zhao, Qi Tang, Haoyu Yan, Feng Li, Xi Ma   +8 more
wiley   +1 more source

New Mucoadhesive Polymeric Film for Ophthalmic Administration of Acetazolamide

Recent Patents on Drug Delivery & Formulation, 2014
This article reports the results concerning the design and manufacture of a novel polymeric film for ocular administration of acetazolamide (AZM), and a patent document presented to INPI- National Institute of Industrial/Intelectual Property.
Tartara, Luis Ignacio, Palma, Santiago Daniel, Ahumada, Maria I., Allemandi, Daniel Alberto, Llabot, Juan Manuel   +4 more
openaire   +3 more sources

Effect of Hyaluronic Acid on Palatal Wound Healing—A Randomized Crossover Clinical Trial

Clinical Oral Implants Research, EarlyView.
ABSTRACT Aim To assess the effect of a hyaluronic acid (HyA) containing gel on patient‐related outcomes (PRO) and wound healing after palatal punch‐biopsy representing a free gingival graft. Material and Methods A punch‐biopsy (6 mm diameter, 2 mm thickness) was harvested from one side of the palate at Day 0 and from the contralateral side at Day 21 ...
Madeleine Dahi, Sara Amash, Kristina Bertl, Florian Beck, Patrick Heimel, Andreas Stavropoulos   +5 more
wiley   +1 more source

Formulation and Evaluation of Mucoadhesive Vaginal Film

International Journal of Pharmaceutical Research and Applications
Objective: The objective of the present work is to Formulate and evaluate mucoadhesive vaginal film for Treatment of vaginal infection. Experimental Work: Women are frequently affected with vulvovaginitis, or inflammation of the vulva and vagina. In this study, a novel approach is developed to manage the vaginal infection.
Patel Shaishvi Rajesh, Prajapati Nirali Anilkumar, Hitesh Jain Hitesh Jain, D.B. Meshram D.B. Meshram   +3 more
openaire   +1 more source

Polymeric Based Mucoadhesive Film for CannabidiolControl Release

, 2023
Abstract Cannabidiol is a non-psychoactive cannabinoid isolated from the cannabis plant. Instead of intoxicating effects, Cannabidiol is known for its antioxidant, anti-inflammatory, and anti-anxiety effects. Being antagonist to CB1 and CB2 cannabinoid receptors, Cannabidiol binds to CB receptors through negative allosteric modulation; reduce ...
Wacharakul Laoasoke, Chasuda Choipang, Sonthaya Chaiarwut, Orawan Suwantong, สถาบันวิจัยจุฬาภรณ์ อาคารวิจัยเคมี Chuysinuan, Supanna Techasakul, Pakakrong Sangsanoh, Pitt Supaphol   +7 more
openaire   +1 more source

Gastroretentive microparticles for drug delivery applications [PDF]

, 2011
Many strategies have been proposed to explore the possibility of exploiting gastroretention for drug delivery. Such systems would be useful for local delivery, for drugs that are poorly soluble at higher pH or primarily absorbed from the proximal small ...
Conway, Barbara R, Barbara R. Conway, Adeola Adebisi, Adebisi, Adeola, Conway, Barbara R., Adebisi, Adeola O.   +5 more
core   +1 more source

FORMULATION AND OPTIMIZATION OF MUCOADHESIVE BUCCAL FILM FOR NICOTINE REPLACEMENT THERAPY

, 2023
Objective: Nicotine replacement therapy (NRT) is a widely used method for reducing the desire to smoke and managing withdrawal symptoms during smoking cessation efforts.
PASWAN, SURESH K., SAINI, T. R., SONI, PRAKASH K., PRAKASH, AADITAYA   +3 more
core   +1 more source