Results 41 to 50 of about 1,383,541 (213)

Optimasi Hidroksipropil Metilselulosa dan Polivinil Pirolidon dalam Sediaan Mucoadhesive Buccal Film Diltiazem Hidroklorida [PDF]

open access: yes, 2021
Diltiazem HCl is a class of benzodiazepine calcium channel blockers used to treat angina pectoris, arrhythmias, and hypertension. Diltiazem HCl improves first-pass metabolism, a short half time of 3-5 hours, and bioavailability of diltiazem for oral ...
Wicaksono, Yudi   +2 more
core   +1 more source

Comparative Analysis of the Functional Properties of Films Based on Carrageenans, Chitosan, and Their Polyelectrolyte Complexes

open access: yesMarine Drugs, 2021
The influence of the structural features of carrageenan on the functional properties of the films was studied. The carrageenans and chitosan films, as well as three-layer films containing a polyelectrolyte complex (PEC) of the two, were prepared.
Aleksandra V. Volod’ko   +5 more
doaj   +1 more source

Development and Characterization of an Amorphous Solid Dispersion of Furosemide in the Form of a Sublingual Bioadhesive Film to Enhance Bioavailability

open access: yesPharmaceutics, 2017
Administered by an oral route, Furosemide (FUR), a diuretic used in several edematous states and hypertension, presents bioavailability problems, reported as a consequence of an erratic gastrointestinal absorption due to various existing polymorphic ...
Viviana De Caro   +5 more
doaj   +1 more source

Comparative Study of Different Combinational Mucoadhesive Formulations of Sumatriptan-Metoclopramide [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2016
Purpose: Sumatriptan succinate (Sum) is a Serotonin 5- HT1 receptor agonist, used in the treatment of migraine. It is absorbed rapidly but incompletely when taken orally and underwent first - pass metabolism, resulting in a low bioavailability of about ...
Mitra Jelvehgari   +5 more
doaj   +1 more source

Intranasal Zolmitriptan-Loaded Bilosomes with Extended Nasal Mucociliary Transit Time for Direct Nose to Brain Delivery

open access: yesPharmaceutics, 2021
This study aimed at delivering intranasal zolmitriptan directly to the brain through preparation of bilosomes incorporated into a mucoadhesive in situ gel with extended nasal mucociliary transit time.
Mai M. El Taweel   +3 more
doaj   +1 more source

Biodegradable and Biocompatible Functional Polymers for Biomedical Applications

open access: yesAdvanced Functional Materials, EarlyView.
Biodegradable and biocompatible functional polymers integrate electrical, mechanical, and stimuli‐responsive functionalities while enabling programmed degradation under physiological conditions. This review introduces recent advances in conductive, shape‐memory, self‐healing, photocurable, and adhesive polymer systems, emphasizing material design ...
Won Bae Han   +5 more
wiley   +1 more source

Quality by Design-Guided Systematic Development and Optimization of Mucoadhesive Buccal Films

open access: yesPharmaceutics, 2023
Mucoadhesive buccal films have found increased popularity in pharmaceutical drug delivery due to the several advantages that they possess. The present study strives to develop and optimize chitosan-based mucoadhesive buccal films by relying on quality-by-
Alharith A. A. Hassan   +4 more
doaj   +1 more source

Programmable Pneumatic Actuator System for a Bioinspired Artificial Colon

open access: yesAdvanced Materials Technologies, EarlyView.
A modular soft robotic colon simulator driven by programmable pneumatic actuation is developed to mimic physiological and pathological‐like motility patterns of the large intestine. Finite element–guided design and distributed control enable anatomically realistic deformation for peristalsis, segmentation, and mass movements, supporting capsule ...
Andrew Bickerdike   +6 more
wiley   +1 more source

Understanding Dutch film culture: a comparative approach [PDF]

open access: yes, 2013
In terms of cinema attendance, the Netherlands has always differed from other European countries. During the first decade of permanent film exhibition—a crucial phase in cinema’s development as a mass medium—the movies failed to gain a firm foothold in ...
Thissen, Judith   +4 more
core   +2 more sources

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

open access: yesAdvanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib   +8 more
wiley   +1 more source

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