Results 31 to 40 of about 1,383,541 (213)
Mucoadhesive buccal films of glibenclamide: Development and evaluation
International Journal of Pharmaceutical Investigation, 2011 Glibenclamide is an oral hypoglycemic drug completely metabolized in the liver, the principal metabolite being very weakly active, buccal delivery may be useful for the treatment of diabetes more effectively. The aim of the present study was to design formulations and systematically evaluate in vitro and ex vivo performances of buccal films of ...
Muzib, Y Indira, Kumari, K Srujana
openaire +3 more sources
Journal of Functional Biomaterials, 2021 Background: The study aimed at assessing the mucoadhesive properties and the barrier effect of a formulation, labelled as AL2106, containing sodium chondroitin sulfate (ChS), xyloglucan from tamarind seed extract, and glycerol, by evaluating the capacity
Tiziana Maria Grazia Pecora +6 more
doaj +1 more source
An Optimasi Polivinil Pirolidon dan Kitosan dalam Sediaan Mucoadhesive Buccal Film Diltiazem HCl [PDF]
, 2020 Diltiazem HCl adalah golongan benzoatiazepin penghambat kanal kalsium (calcium channel blocker) yang digunakan dalam pengobatan angina pektoris, aritmia, dan hipertensi. Diltiazem HCl mengalami first pass metabolism di hati, waktu paruh yang pendek yakni
Rosyidi, Viddy Agustian +2 more
core +1 more source
A multilayered nanofibrous mucoadhesive system for chamomile and Lidocaine controlled delivery in aphthous [PDF]
Nanomedicine JournalObjective(s): The mucoadhesive systems are among the preferred dosage forms for oral disorders. They can be designed to concentrate the drug at the site of action, control the drug release, and reduce both the frequency of medication and the systemic ...
Zeynab Ahmadifard +3 more
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The formulation of mucoadhesive drug form for topical application in the oral cavity - application, manufacturing technology and testing methods [PDF]
Farmacja Polska, 2021 There are over four hundred different diseases occurring within the oral cavity. These include, among others, mucositis, periodontitis, gingivitis, caries, oral infections, which are usually treated topically. Active substances for topical application in
Michał Krzysztof Kołodziejczyk +4 more
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Formulation and evaluation of mucoadhesive buccal films of enalapril maleate
Indian Journal of Pharmaceutical Sciences, 2010 Enalapril maleate is used in the treatment of hypertension and angina pectoris. It shows low bioavailability due to high hepatic first pass metabolism. Hence the present work was undertaken to formulate mucoadhesive buccal films of enalapril maleate with an objective to improve therapeutic efficacy, patient compliance and the bioavailability.
Semalty, A, Semalty, Mona, Nautiyal, U
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Marine Drugs, 2020 Women are still at high risk of contracting the human immunodeficiency virus (HIV) virus due to the lack of protection methods under their control, especially in sub-Saharan countries.
Raúl Cazorla-Luna +7 more
doaj +1 more source
In Vitro Evaluation of Mucoadhesive Films for Gingival Administration of Lidocaine [PDF]
AAPS PharmSciTech, 2013 The aim of this study was the optimization of a lidocaine-based film formulation for the prevention of pain from needle prick during the injection of local anesthetic in dentistry. Film performances were evaluated in vitro by studying lidocaine permeation across pig esophageal epithelium as model for nonkeratinized buccal mucosa.
PADULA, Cristina +4 more
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Development of Imiquimod-Loaded Mucoadhesive Films for Oral Dysplasia [PDF]
Journal of Pharmaceutical Sciences, 2013 Oral squamous dysplasia, which can usually be readily visualized as leukoplakia during an oral examination and confirmed by histology, is often considered a premalignant condition. Current treatments, however, focus on the final stages of disease, and treatments such as surgery can lead to postoperative disabilities.
Sandeep K, Ramineni +3 more
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Illustration of the mucoadhesive film production.
, 2016 Illustration of the mucoadhesive film production.
Rodney Alexandre Ferreira Rodrigues (3119697) +10 more
core +1 more source