Results 11 to 20 of about 1,383,541 (213)
Optimization of Hydroxy Propyl Methyl Cellulose and Carbomer In Diltiazem Hydrochloride Mucoadhesive Buccal Film [PDF]
Indonesian Journal of Pharmacy, 2021 Diltiazem hydrochloride (HCl) is a category of calcium channel blocker used as an antihypertensive agent. Diltiazem HCl is a low bioavailable drug due to high first-pass metabolism and a short half-life (3-5 hours); hence mucoadhesive buccal film was ...
Lina Winarti +2 more
doaj +3 more sources
Concept of Orodispersible or Mucoadhesive “Tandem Films” and Their Pharmaceutical Realization [PDF]
Pharmaceutics, 2022 Orodispersible or mucoadhesive films as a patient-oriented dosage form for low-dosed drugs are usually produced using solvent casting. This paper presents a modification of the solvent casting technique that aimed to divide oral films into two or more ...
Anja Göbel, Jörg Breitkreutz
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Formulation and Characterization of Captopril-Loaded Chitosan Mucoadhesive Buccal Films with Different Permeation-Enhancing Components [PDF]
PharmaceuticsBackground/Objectives: The buccal mucosa offers a promising non-invasive route for systemic drug delivery, particularly for hydrophilic compounds like captopril (CAP), which exhibit low permeability and are subject to gastrointestinal instability and ...
Hala Rayya +7 more
doaj +2 more sources
Enhanced gastrointestinal survivability of recombinant Lactococcus lactis using a double coated mucoadhesive film approach. [PDF]
PLoS ONE, 2019 Vaccine administration via the oral route is preferable to parenteral routes due to ease of administration. To date, most available oral vaccines comprises of live attenuated pathogens as oppose to peptide-based vaccines due to its low bioavailability ...
Ee Wern Tan +4 more
doaj +2 more sources
Mucoadhesive Gelatin Buccal Films with Propranolol Hydrochloride: Evaluation of Mechanical, Mucoadhesive, and Biopharmaceutical Properties [PDF]
Pharmaceutics, 2021 This study processes and characterizes propranolol hydrochloride/gelatin mucoadhesive buccal films. Two types of gelatin are used: Gelatin from porcine skin, type A (GA), and gelatin from bovine skin (GB). The influence of gelatin type on mechanical, mucoadhesive, and biopharmaceutical characteristics of buccal films is evaluated.
Marija Jovanović +5 more
openaire +6 more sources
International Journal of Current Pharmaceutical Research, 2021 The buccal route of administration has many advantages, including gastrointestinal bypass surgery and first pass through the liver. The mucoadhesive membrane is a retention dosage form that can release the drug directly into the biological matrix. Cheek technology has proven to be an advanced alternative to other traditional devices.
SINDHU G. D. +2 more
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Journal of Industrial Textiles, 2022 In the present study a double layer mucoadhesive buccal film containing nanocarriers encapsulated with neem extract was fabricated through electrospinning and solvent casting techniques for dental therapeutic applications. The morphological, physical and
Anahita Rohani Shirvan +3 more
doaj +1 more source
Mucoadhesion and Mechanical Assessment of Oral Films
European Journal of Pharmaceutical Sciences, 2021 Aligned with efforts to overcome shortcomings of conventional oral dosage forms, mucoadhesive oral thin films have been the focus of drug development. Transmucosal drug delivery through oral cavity is a popular alternative to deliver many drugs due to several advantages over conventional oral delivery including greater bioavailability due to bypassing ...
Samaneh Alaei, Hamid Omidian
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Development of Mucoadhesive Buccal Film for Rizatriptan: In Vitro and In Vivo Evaluation
Pharmaceutics, 2021 The reduced therapeutic efficacy of rizatriptan in migraine treatment is primarily due to low oral bioavailability and extensive first pass metabolism. The purpose of this investigation was to optimize the thin mucoadhesive buccal film of rizatriptan and
Anroop B. Nair +6 more
doaj +1 more source
Molecules, 2023 Taraxaci folium and Matricariae flos plant extracts contain a wide range of bioactive compounds with antioxidant and anti-inflammatory effects. The aim of the study was to evaluate the phytochemical and antioxidant profile of the two plant extracts to ...
Oana Mihaela Neagu +12 more
doaj +1 more source