Design and evaluation of sustained release mucoadhesive film of sumatriptan succinate containing grafted co-polymer as the platform [PDF]
Saudi Pharmaceutical Journal, 2022 Purpose: The primary goal of this research is to improve the bioavailability and efficacy of Sumatriptan succinate by incorporating it in the mucoadhesive film for the treatment of migraine. Mucoadhesive film offers an excellent substitute to deliver the
Surajpal Verma +9 more
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Mucoadhesive film containing α-mangostin shows potential role in oral cancer treatment [PDF]
BMC Oral Health, 2021 Background Oral cancer is often preceded by a mucosal lesion called an oral potentially malignant disorder (OPMD). Many plant-derived compounds are of value in medicine.
Piyawat Tangsuksan +7 more
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Three-Dimensional Printing of an Apigenin-Loaded Mucoadhesive Film for Tailored Therapy to Oral Leukoplakia and the Chemopreventive Effect on a Rat Model of Oral Carcinogenesis [PDF]
Pharmaceutics, 2022 Oral leukoplakia, which presents as white lesions in the oral cavity, including on the tongue, is precancerous in nature. Conservative treatment is preferable, since surgical removal can markedly reduce the patient’s quality of life. In the present study,
Hiroyuki Takashima +5 more
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Improved Bioavailability of Montelukast through a Novel Oral Mucoadhesive Film in Humans and Mice [PDF]
Pharmaceutics, 2020 The leukotriene receptor antagonist Montelukast (MTK) is an approved medication for the treatment of asthma and allergic rhinitis. The existing marketed tablet forms of MTK exhibit inconsistent uptake and bioavailability, which partially explains the ...
Johanna Michael +10 more
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Evaluation of a curcumin-containing mucoadhesive film for periodontal postsurgical pain control [PDF]
Journal of Indian Society of Periodontology, 2019 Background: Management of pain and discomfort is important to make the postoperative period as pleasant as possible. Nonsteroidal anti-inflammatory drugs are traditionally prescribed; however, they are associated with numerous side effects.
Anu Anil +2 more
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Development and Evaluation of a Novel Mucoadhesive Film Containing Acmella oleracea Extract for Oral Mucosa Topical Anesthesia. [PDF]
PLoS ONE, 2016 PURPOSE:To develop an anesthetic mucoadhesive film containing Acmella oleracea (jambu) extract for topical use on oral mucosa. METHODS:Ethanolic extracts from aerial parts of jambu were prepared by maceration.
Verônica Santana de Freitas-Blanco +10 more
doaj +2 more sources
Design, optimization and characterization of mucoadhesive buccal film as a novel delivery system for doxazosin mesylate [PDF]
Saudi Pharmaceutical JournalDoxazosin mesylate is a selective α1-adrenergic receptor antagonist with low oral bioavailability due to poor aqueous solubility and extensive first-pass hepatic metabolism.
Nidhal Khazaal Maraie, Ali N. Wannas
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Formulation of mucoadhesive dissolving film containing cinnamaldehyde and chitosan incorporating papain enzyme for inhibit oral candidiasis: in vitro study [PDF]
Scientific ReportsObjective: To find a mucoadhesive dissolving film formula based on cinnamaldehyde (C) and shrimp skin chitosan (K) incorporating papain enzyme (P), in order to inhibit oral candidiasis caused by Candida albicans, in diabetes mellitus patients.
Andi Asti Akhriani +7 more
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A novel formulation for radiotherapy-induced oral mucositis: Triamcinolone acetonide mucoadhesive film [PDF]
Journal of Research in Medical Sciences, 2019 Background: The main purpose of this study was to evaluate the effectiveness of triamcinolone acetonide (TA) mucoadhesive films versus placebo as a preventive and therapeutic intervention of oral mucositis (OM) induced by radiotherapy for head-and-neck ...
Fahimeh Pakravan +4 more
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Pharmaceutics, 2021 Currently, pharmaceutical companies are working on innovative methods, processes and products. Oral mucoadhesive systems, such as tablets, gels, and polymer films, are among these possible products.
Krisztián Pamlényi +3 more
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