Results 61 to 70 of about 608,623 (303)

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin   +8 more
wiley   +1 more source

Immunogenicity and efficacy of a rabies-based vaccine against highly pathogenic influenza H5N1 virus

open access: yesEmerging Microbes and Infections
The recent spillover of highly pathogenic influenza A/H5N1 (HPAI-H5N1) viruses to cattle, other mammals, and humans poses a major risk to animal and human health.
Nir Paran   +8 more
doaj   +1 more source

The Interaction of the Gut Microbiota with the Mucus Barrier in Health and Disease in Human

open access: yesMicroorganisms, 2018
Glycoproteins are major players in the mucus protective barrier in the gastrointestinal and other mucosal surfaces. In particular the mucus glycoproteins, or mucins, are responsible for the protective gel barrier.
Anthony P. Corfield
doaj   +1 more source

Understanding the Burden of Orofacial Involvement and Patient Treatment Preferences in Systemic Sclerosis: Results From a Large International Survey

open access: yesArthritis Care &Research, EarlyView.
Objective Orofacial manifestations are significantly impactful in patients with systemic sclerosis (SSc) yet remain understudied, with no dedicated clinical guidelines to inform their management. Methods An international online survey comprised38 questions addressing orofacial manifestations of SSc, including patients’ confidence in their treating ...
Eleni Deligianni   +4 more
wiley   +1 more source

Mucosal melanoma – diagnostic challenge

open access: yes
Mucosal melanoma malignum (mMM) is a rare and aggressive malignancy that carries a poor prognosis. Most commonly, it develops on the mucous membranes in the head and neck region, and within the genitalia. Because of its anatomical location and absence of
Paulina Karp   +2 more
core   +1 more source

Incidence, Risk Factors and Management of Adverse Events in Contemporary Real‐World Care of Children with Juvenile Idiopathic Arthritis

open access: yesArthritis Care &Research, Accepted Article.
Objective We describe the frequency, risk factors, severity, and management of actionable and serious adverse events (AAE and SAE) in children with newly diagnosed Juvenile Idiopathic Arthritis (JIA) in Canada. Methods We enrolled patients within 3 months of JIA diagnosis in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry,
Bashayer Alnuaimi   +10 more
wiley   +1 more source

Role of IL-17 in modulating B cell response during influenza infection in mice

open access: yes, 2011
The 15th International Congress of Mucosal Immunology (ICMI 2011), Paris, France, 5-9 July ...
Lu, L
core  

Biodegradable and Biocompatible Functional Polymers for Biomedical Applications

open access: yesAdvanced Functional Materials, EarlyView.
Biodegradable and biocompatible functional polymers integrate electrical, mechanical, and stimuli‐responsive functionalities while enabling programmed degradation under physiological conditions. This review introduces recent advances in conductive, shape‐memory, self‐healing, photocurable, and adhesive polymer systems, emphasizing material design ...
Won Bae Han   +5 more
wiley   +1 more source

The science of mucositis [PDF]

open access: yesSupportive Care in Cancer, 2022
Joanne Bowen, Hannah Wardill
openaire   +2 more sources

Chitosan-based mucosal adjuvants: Sunrise on the ocean

open access: yes, 2015
Mucosal vaccination, which is shown to elicit systemic and mucosal immune responses, serves as a non-invasive and convenient alternative to parenteral administration, with stronger capability in combatting diseases at the site of entry.
Fan, Qingze   +5 more
core   +1 more source

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