Results 61 to 70 of about 240,254 (279)
Frontiers in Immunology, 2022 The role of the mucosal pulmonary antibody response in coronavirus disease 2019 (COVID-19) outcome remains unclear. Here, we found that in bronchoalveolar lavage (BAL) samples from 48 patients with severe COVID-19-infected with the ancestral Wuhan virus,
Maria Julia Ruiz +36 more
doaj +1 more source
Salivary immunity and lower respiratory tract infections in non-elite marathon runners [PDF]
, 2018 Peer ReviewedPostprint (published ...
Cantó, Elisabet +11 more
core +4 more sources
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
The Immunoglobulins of Cold-Blooded Vertebrates [PDF]
, 2014 Peer reviewedPublisher ...
Chen +22 more
core +2 more sources
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Rectal Microbiome Composition Correlates with Humoral Immunity to HIV-1 in Vaccinated Rhesus Macaques. [PDF]
, 2019 The microbiome is an integral and dynamic component of the host and is emerging as a critical determinant of immune responses; however, its influence on vaccine immunogenicity is largely not well understood.
Dinasarapu, Ashok R +9 more
core +1 more source
Mucosal Immunity/Mucosal Vaccine
Nippon Shokuhin Kagaku Kogaku Kaishi, 2009 ヒトや動物には，外敵から身体を守るために免疫系が備わっている．多くのウイルスや病原菌の侵入口である粘膜面には効果的な「粘膜免疫」が存在し，抗原特異的分泌型IgA応答や細胞障害性T細胞（CTL）を誘導する．各粘膜は共通粘膜免疫機構（common mucosal immune system（CMIS））により関連をもち，ある粘膜組織で誘導されたIgA産生細胞やCTLは他の粘膜組織にも帰巣（ホーミング）する．とくに，分泌型IgA産生細胞は，腸管関連リンパ組織（GALT），鼻咽頭関連リンパ組織（NALT）および気管支関連リンパ組織（BALT）などの誘導組織（inductive site）で誘導され，実効組織（effector site）である腸管粘膜固有層，呼吸器粘膜固有層，乳腺，涙腺，唾液腺 ...
openaire +2 more sources
FEBS Open Bio, EarlyView.KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli +9 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Aims This study aimed to explore the relationship between stress‐induced hyperglycemia (SIH) and in‐hospital medical complications in patients with acute stroke. Methods We enrolled 865,765 patients with acute stroke from the Chinese Stroke Center Alliance cohort.
Xintong Song +6 more
wiley +1 more source