Results 31 to 40 of about 5,453 (193)

Putting bicarbonate on the spot: pharmacological insights for CFTR correction in the airway epithelium

Frontiers in Pharmacology, 2023
Introduction: Cystic fibrosis (CF) is caused by defective Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) proteins. CFTR controls chloride (Cl−) and bicarbonate (HCO3−) transport into the Airway Surface Liquid (ASL). We investigated the impact
Miroslaw Zajac, Miroslaw Zajac, Miroslaw Zajac, Miroslaw Zajac, Agathe Lepissier, Agathe Lepissier, Agathe Lepissier, Elise Dréano, Elise Dréano, Elise Dréano, Benoit Chevalier, Benoit Chevalier, Benoit Chevalier, Aurélie Hatton, Aurélie Hatton, Aurélie Hatton, Mairead Kelly-Aubert, Mairead Kelly-Aubert, Mairead Kelly-Aubert, Daniela Guidone, Gabrielle Planelles, Aleksander Edelman, Aleksander Edelman, Aleksander Edelman, Emmanuelle Girodon, Emmanuelle Girodon, Alexandre Hinzpeter, Alexandre Hinzpeter, Alexandre Hinzpeter, Gilles Crambert, Iwona Pranke, Iwona Pranke, Iwona Pranke, Luis. J. V. Galietta, Isabelle Sermet-Gaudelus, Isabelle Sermet-Gaudelus, Isabelle Sermet-Gaudelus, Isabelle Sermet-Gaudelus   +37 more
doaj   +1 more source

Role of Host and Bacterial Lipids in Pseudomonas aeruginosa Respiratory Infections

Frontiers in Immunology, 2022
The opportunistic pathogen Pseudomonas aeruginosa is one of the most common agents of respiratory infections and has been associated with high morbidity and mortality rates. The ability of P. aeruginosa to cause severe respiratory infections results from
Pamella Constantino-Teles, Albane Jouault, Lhousseine Touqui, Alessandra Mattos Saliba   +3 more
doaj   +1 more source

Prevalência da mutação ΔF508 no gene cystic fibrosis transmembrane conductance regulator em pacientes com fibrose cística em um centro de referência no Brasil

Jornal de Pediatria, 2012
OBJETIVO: Verificar a presença da mutação ΔF508 no gene cystic fibrosis transmembrane conductance regulator na população de pacientes com fibrose cística, diagnosticados pelo teste de sódio e cloro no suor, em acompanhamento no Ambulatório de Pneumologia
Andréia Marisa Bieger, Fernando Augusto de Lima Marson, Carmen Sílvia Bertuzzo   +2 more
doaj   +1 more source

Methotrexate does not affect lung function in children with juvenile idiopathic arthritis

, 2023
Pediatric Pulmonology, Volume 58, Issue 12, Page 3630-3636, December 2023.
Thomas Perrin, Laurianne Coutier, Julien Ranchoup, Anas Rifard, Mathilde Eymery, Camille Ohlmann, Marie‐Christine Werck‐Gallois, Audrey Laurent, Marine Desjonquères, Agnès Duquesne, Alexandre Belot, Philippe Reix   +11 more
wiley   +1 more source

The Prognosis of ART Is Not Altered in Cystic Fibrosis Women: A Case-Report Study

Frontiers in Endocrinology, 2022
Research QuestionUnlike in men, a very limited number of studies were focused on the specificity of ART management of cystic fibrosis (CF) in women. The purpose of this study was to determine the causes of infertility in patients, the appropriate ART ...
Inès Braham, Adeline Morisot, Samir Boukaïdi, Marie Perceval, Isabelle Durieu, Christine Rousset-Jablonski, Sylvie Hieronimus, Sylvie Leroy, Nicolas Chevalier, Nicolas Chevalier   +9 more
doaj   +1 more source

Neonatal low respiratory tract chlamydia trachomatis infection: Diagnostic and treatment management

Respiratory Medicine Case Reports, 2019
Maternal infection during pregnancy by Chlamydia trachomatis (Chlamydia t.) can result in neonatal interstitial lung disease. It remains difficult for physicians to establish this diagnosis and to select the best treatment, as there is no recommendation.
M. Jouglet, I. Wuillaume, C. Buchs, P. Reix, C. Schweitzer, L. Coutier   +5 more
doaj   +1 more source

Diagnostic néonatal et recompositions temporelles: Le cas de la mucoviscidose [PDF]

, 2014
International audienceCet article a pour objectif de reconstituer la structuration temporelle qui cadre le protocole diagnostique et l’annonce d’une maladie rare, la mucoviscidose.
Langeard, Chloé, Minguet, Guy
core   +5 more sources

TLR3 promotes MMP-9 production in primary human airway epithelial cells through Wnt/β-catenin signaling

Respiratory Research, 2017
Background Airway epithelial cells (AEC) act as the first line of defence in case of lung infections. They constitute a physical barrier against pathogens and they participate in the initiation of the immune response.
P.-J. Royer, K. Henrio, M. Pain, J. Loy, A. Roux, A. Tissot, P. Lacoste, C. Pison, S. Brouard, A. Magnan, the COLT consortium   +10 more
doaj   +1 more source

The gut-lung axis in the CFTR modulator era

Frontiers in Cellular and Infection Microbiology, 2023
The advent of CFTR modulators represents a turning point in the history of cystic fibrosis (CF) management, changing profoundly the disease’s clinical course by improving mucosal hydration.
Florian Lussac-Sorton, Florian Lussac-Sorton, Éléna Charpentier, Éléna Charpentier, Sébastien Imbert, Sébastien Imbert, Sébastien Imbert, Maxime Lefranc, Stéphanie Bui, Stéphanie Bui, Stéphanie Bui, Michael Fayon, Michael Fayon, Michael Fayon, Patrick Berger, Patrick Berger, Patrick Berger, Raphaël Enaud, Raphaël Enaud, Raphaël Enaud, Laurence Delhaes, Laurence Delhaes, Laurence Delhaes   +22 more
doaj   +1 more source

Mécanismes et conséquences des mutations [PDF]

, 2005
L’identification des mutations à l’origine de maladies génétiques chez l’homme a pris ces dernières années un essor considérable. Il est devenu possible d’établir le spectre des mutations délétères pour une maladie génétique donnée, et des bases de ...
Hanna, Nadine, Parfait, Béatrice, Vidaud, Dominique, Vidaud, Michel   +3 more
core   +1 more source