Results 51 to 60 of about 760 (134)

Acyl Carrier Protein is essential for MukBEF action inEscherichia colichromosome organization-segregation [PDF]

, 2021
AbstractStructural Maintenance of Chromosomes (SMC) complexes contribute ubiquitously to chromosome organization-segregation. SMC proteins have a conserved architecture, with a dimerization hinge and an ATPase head domain separated by a long antiparallel intramolecular coiled-coil.
Josh P. Prince, Jani R. Bolla, Gemma L. M. Fisher, Jarno Mäkelä, Carol V. Robinson, Lidia K. Arciszewska, David J. Sherratt   +6 more
openaire   +1 more source

Independent mobility of proteins and lipids in the plasma membrane of Escherichia coli [PDF]

, 2016
Biotechnology and Biological Sciences Research Council. Grant Number: BB/E009571, Oxford Centre for Integrative Systems Biology (OCISB), Engineering and Physical Science Research Council, Royal Society, Hertford College ...
Leake, MC, Lenn, T, Mastroianni, G, Mullineaux, CW, Nenninger, A, Robson, A, Xue, Q   +6 more
core   +1 more source

MukBEF on the march: taking over chromosome organization in bacteria? [PDF]

Molecular Microbiology, 2011
SummarySmc–ScpAB complexes, also called bacterial condensin, are comprised of highly conserved proteins present in a wide variety of bacteria and archaea. They facilitate bacterial chromosome segregation probably by organizing and/or compacting nascent sister chromosomes.
openaire   +3 more sources

High-resolution definition of the Vibrio cholerae essential gene set with hidden Markov model–based analyses of transposon-insertion sequencing data [PDF]

, 2014
The coupling of high-density transposon mutagenesis to high-throughput DNA sequencing (transposon-insertion sequencing) enables simultaneous and genome-wide assessment of the contributions of individual loci to bacterial growth and survival.
Chao, Michael C., Davis, Brigid M., Livny, Jonathan, Pritchard, Justin R., Rubin, Eric J., Waldor, Matthew K., Zhang, Yanjia J.   +6 more
core   +1 more source

ATP-Induced Shrinkage of DNA with MukB Protein and the MukBEF Complex of Escherichia coli [PDF]

Journal of Bacteriology, 2008
ABSTRACT Fluorescence microscopic observation of individual T4 DNA molecules revealed that the MukBEF complex (bacterial condensin) and its subunit, the MukB (a member of the SMC [structural maintenance of chromosomes] superfamily) homodimer, of Escherichia coli markedly shrunk large DNA molecules in the ...
Ning, Chen, Anatoly A, Zinchenko, Yuko, Yoshikawa, Sumiko, Araki, Shun, Adachi, Mitsuyoshi, Yamazoe, Sota, Hiraga, Kenichi, Yoshikawa   +7 more
openaire   +2 more sources

The ABCs of SMC proteins: two-armed ATPases for chromosome condensation, cohesion and repair [PDF]

, 2002
The first draft of the human genome sequence was reported a year ago. It may be a good time to remind ourselves that the genetic information encoded in the ∼3000-Mb sequence is stored not only in the public or private databases but also in the tiny space
Hirano, T.
core   +1 more source

Novobiocin Susceptibility of MukBEF-Deficient Escherichia coli Is Combinatorial with Efflux and Resides in DNA Topoisomerases [PDF]

Antimicrobial Agents and Chemotherapy, 2016
ABSTRACT Condensins play a key role in the global organization of bacterial chromosomes. In Escherichia coli , the inactivation of its sole condensin MukBEF induces severe growth defects and renders cells hypersusceptible to novobiocin.
Zoya M, Petrushenko, Hang, Zhao, Helen I, Zgurskaya, Valentin V, Rybenkov   +3 more
openaire   +2 more sources

Capturing chromosome conformation in Crenarchaea

Molecular Microbiology, Volume 123, Issue 2, Page 101-108, February 2025.
To fit into cells, chromosomes must be folded. Here we describe how members of the Archaea effect this folding process and how chromosome architecture both influences and is influenced by gene expression. Abstract While there is a considerable body of knowledge regarding the molecular and structural biology and biochemistry of archaeal information ...
Elyza Pilatowski‐Herzing, Rachel Y. Samson, Naomichi Takemata, Catherine Badel, Peter B. Bohall, Stephen D. Bell   +5 more
wiley   +1 more source

Mutational analysis of MukE reveals its role in focal subcellular localization of MukBEF [PDF]

Molecular Microbiology, 2012
SummaryBacterial condensin MukBEF is essential for global folding of the Escherichia coli chromosome. MukB, a SMC (structural maintenance of chromosome) protein, comprises the core of this complex and is responsible for its ATP‐modulated DNA binding and reshaping activities.
Weifeng, She, Elena, Mordukhova, Hang, Zhao, Zoya M, Petrushenko, Valentin V, Rybenkov   +4 more
openaire   +2 more sources

Rok from B. subtilis: Bridging genome structure and transcription regulation

Molecular Microbiology, Volume 123, Issue 2, Page 109-123, February 2025.
In our review on the dual role of B. subtilis Rok as genome organizer and gene regulator, we argue that these two functions are in fact two sides of the same coin and that the coupling between them should be taken into account in further research. We also propose a list of characteristics to aid in determining whether a protein belongs to the H‐NS‐like
Amanda M. Erkelens, Bert van Erp, Wilfried J. J. Meijer, Remus T. Dame   +3 more
wiley   +1 more source