Results 31 to 40 of about 775 (136)
The Plant Journal, Volume 115, Issue 4, Page 1084-1099, August 2023., 2023 Significance Statement The understanding of the role of the structural maintenance of chromosomes (SMC) 5/6 complexes in plants, particularly of the NSE5 and NSE6 subunits, is poor. We identified a previously unrecognized NSE6 motif mediating interaction with NSE5 and mapped the Physcomitrium patens PpNSE6‐binding site at the PpSMC5 arm. These findings
Edit Lelkes +9 more
wiley +1 more source
BioMed Research International, Volume 2023, Issue 1, 2023., 2023 As an omnipresent opportunistic bacterium, Pseudomonas aeruginosa PAO1 is responsible for acute and chronic infection in immunocompromised individuals. Currently, this bacterium is on WHO’s red list where new antibiotics are urgently required for the treatment.
Atikur Rahman +6 more
wiley +1 more source
The Role of MukE in Assembling a Functional MukBEF Complex [PDF]
Journal of Molecular Biology, 2011 The MukB-MukE-MukF protein complex is essential for chromosome condensation and segregation in Escherichia coli. The central component of this complex, the MukB protein, is related functionally and structurally to the ubiquitous SMC (structural maintenance of chromosomes) proteins.
Melanie, Gloyd +2 more
openaire +2 more sources
Non-random segregation of sister chromosomes byEscherichia coliMukBEF axial cores [PDF]
SSRN Electronic Journal, 2020 SummaryTheEscherichia colistructural maintenance of chromosomes complex, MukBEF, forms axial cores to chromosomes that determine their spatio-temporal organization. Here, we show that axial cores direct chromosome arms to opposite poles and generate the translational symmetry between newly replicated sister chromosomes.
Jarno Mäkelä +2 more
openaire +2 more sources
Environmental Microbiology, Volume 23, Issue 6, Page 3318-3331, June 2021., 2021 Summary Rok, a Bacillus subtilis nucleoid‐associated protein (NAP), negatively regulates competence development and silences xenogeneic genes. We show that rok inactivation increases rpoB482 natural intraspecies chromosomal transformation (CT) and plasmid transformation to a different extent.
Ester Serrano +2 more
wiley +1 more source
Journal of Cellular Physiology, Volume 236, Issue 5, Page 3579-3598, May 2021., 2021 The condensin II complex mutations R551P, R551S, and S556F cause genomic instability by causing DNA damage, anaphase defects, micronuclei, and chromosomal instability. DNA damage and anaphase defects are caused primarily by ataxia telangiectasia and Rad3‐related‐dependent telomere dysfunction.
Emily Weyburne, Giovanni Bosco
wiley +1 more source
BioEssays, Volume 43, Issue 4, April 2021., 2021 DNA topoisomerases are fundamental to the life of all cells due to their numerous roles in DNA metabolic processes; this includes transcription, replication, chromosome segregation, DNA repair, neurodevelopment, tumour suppression, mitochondrial DNA maintenance, and RNA processing, with new roles still being actively elucidated 50 years after their ...
Shannon J. McKie +2 more
wiley +1 more source
The MaoP/maoS Site-Specific System Organizes the Ori Region of the E. coli Chromosome into a Macrodomain. [PDF]
PLoS Genetics, 2016 The Ori region of bacterial genomes is segregated early in the replication cycle of bacterial chromosomes. Consequently, Ori region positioning plays a pivotal role in chromosome dynamics. The Ori region of the E.
Michèle Valens +2 more
doaj +1 more source
Distinct Activities of Bacterial Condensins for Chromosome Management in Pseudomonas aeruginosa
Cell Reports, 2020 Summary: Three types of structurally related structural maintenance of chromosomes (SMC) complexes, referred to as condensins, have been identified in bacteria.
Virginia S. Lioy +4 more
doaj +1 more source
Molecular basis for SMC rod formation and its dissolution upon DNA binding. [PDF]
, 2015 SMC condensin complexes are central modulators of chromosome superstructure in all branches of life. Their SMC subunits form a long intramolecular coiled coil, which connects a constitutive "hinge" dimerization domain with an ATP-regulated "head ...
Alipour +57 more
core +6 more sources