Results 71 to 80 of about 39,694 (292)
Journal of Social Science Education, 2008 The present research on the development of citizenship education in (transformation) countries fails to ac-knowledge that systems of citizenship education are political organisations by nature. This research does not analyse citizenship education (CE) as
Reinhold Hedtke, Tatjana Zimenkova
doaj +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Social policy and international interventions in South East Europe: conclusions [PDF]
, 2007 This book has brought together three fields of study; that concerned with the role of international actors and their influence on national polices; changes taking place to social policies in the context of globalisation, transnationalism and ...
Deacon, Bob +2 more
core
Insights in the cost of continuous broadband Internet on trains for multi-service deployments by multiple actors with resource sharing [PDF]
, 2014 The economic viability of broadband Internet services on trains has always been proved difficult, mainly due to a high investment cost and low willingness to pay by train passengers, but also due to unused opportunities such as non-passenger services (e ...
Colle, Didier +4 more
core +2 more sources
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Geo: Geography and EnvironmentAs climate change makes the future of urban living appear increasingly daunting, many people and communities are already experiencing climate impacts.
J. E. Goncalves, N. Narendra, T. Verma
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Collaboration and complexity: an experiment on the effect of multi-actor coupled design [PDF]
, 2016 Design of complex systems requires collaborative teams to overcome limitations of individuals; however, teamwork contributes new sources of complexity related to information exchange among members.
De Weck, Olivier L, Grogan, Paul T.
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Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Ironi Sampah dan Pariwisata: Respon Multiaktor atas Krisis Sampah di Kawasan Wisata Kaliurang
Gadjah Mada Journal of Tourism StudiesThe massive development of tourism in the Kaliurang area of Yogyakarta over several decades has had a significant impact on environmental changes, both physical and non-physical.
Runavia Mulyasari, Vania Sekar Widyawati
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