Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
An Expert Based Multi Attribute Group Decision Making (MAGDM) Model for Portfolio Evaluation: Application on Ground Force Units [PDF]
, 2013 This main objective of this dissertation is to propose an expert based multi attribute group decision making model (MAGDM) for portfolio evaluation and demonstrate it by applying it to evaluate brigade types under different military missions ...
Gultekin, Metin
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Fuzzy Interval-Valued Multi Criteria Based Decision Making for Ranking Features in Multi-Modal 3D Face Recognition [PDF]
, 2017 Soodamani Ramalingam, 'Fuzzy interval-valued multi criteria based decision making for ranking features in multi-modal 3D face recognition', Fuzzy Sets and Systems, In Press version available online 13 June 2017.
Ramalingam, Soodamani
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A method to solve Multi-attribute Group linguistic Decision-Making problems [PDF]
Proceedings on Intelligent Systems and Knowledge Engineering (ISKE2007), 2007 This paper presents a method to solve multiattribute group decision-making with linguistic assessment. The method is based on the use of fuzzy linguistic approach, and on the use of fuzzy majority of consensus, represented by means of a linguistic quantifier.
Fang An Deng, Zheng Pei, Hua Zhao
openaire +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Cumulative dominance and heuristic performance in binary multi-attribute choice [PDF]
, 2005 Working paper 895, Department of Economics and Business, Universitat Pompeu FabraSeveral studies have reported high performance of simple decision heuristics in multi-attribute decision making.
Baucells, M +2 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Contractors Perspective on the Selection of Innovative Sustainable Technologies for Achieving Zero Carbon Retail Buildings [PDF]
, 2014 The use of innovative sustainable technologies (IST) has been regarded as an effective approach to enhancing energy efficiency and reducing carbon emissions of buildings. However, contractors face significant challenges in the selection of IST.
Fuertes, A +3 more
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Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Homologous expression and purification of human HAX‐1 for structural studies
FEBS Open Bio, EarlyView.This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source