Results 21 to 30 of about 7,245,224 (256)

EVALUATING RISK FACTORS FOR MULTI DRUG RESISTANCE POST LIVING DONOR LIVER TRANSPLANTATION. [PDF]

open access: yesAl-Azhar Journal of Pharmaceutical Sciences, 2013
Living donor liver transplantation (LDLT) has been used for end stage liver disease (ESLD) since 1989. LDLT has basically resolved the problem of donor organ shortages.
Sarah Osman
doaj   +1 more source

Nitroheterocyclic drug resistance mechanisms in Trypanosoma brucei [PDF]

open access: yes, 2016
Objectives The objective of this study was to identify the mechanisms of resistance to nifurtimox and fexinidazole in African trypanosomes. Methods Bloodstream-form Trypanosoma brucei were selected for resistance to nifurtimox and fexinidazole by ...
Kelner, Anna   +5 more
core   +1 more source

Psychogenetic, genetic and epigenetic mechanisms in Candida auris: Role in drug resistance

open access: yesJournal of Infection and Public Health, 2023
In recent years, we are facing the challenge of drug resistance emergence in fungi. The availability of limited antifungals and development of multi-drug resistance in fungal pathogens has become a serious concern in the past years in the health sector ...
Ali A. Rabaan   +18 more
doaj   +1 more source

Shock caused by multidrug-resistant Erysipelothrix rhusiopathiae bacteremia: a rare case report and literature review

open access: yesJournal of Infection in Developing Countries, 2017
Erysipelothrix rhusiopathiae infection occurs in animals and humans. It manifests primarily as a local skin lesion, which can be treated with antibiotics. Systemic infection with E. rhusiopathiae is rare, with low occurrence of bacteremia. We describe a
Zhenning Liu, Min Zhao
doaj   +1 more source

Drug resistance characteristics of Salmonella isolated from diarrheal patients in Shunyi, Beijing

open access: yesZhongguo shipin weisheng zazhi, 2021
ObjectiveTo study the drug resistance characteristics of Salmonella isolated from diarrheal patients in Shunyi, Beijing.MethodsCollected stool samples of diarrheal patients in Shunyi, Beijing 2013-2018.
JIN Hongwu   +5 more
doaj   +1 more source

Programmatically selected multidrug-resistant strains drive the emergence of extensively drug-resistant tuberculosis in South Africa [PDF]

open access: yes, 2013
South Africa shows one of the highest global burdens of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB). Since 2002, MDR-TB in South Africa has been treated by a standardized combination therapy, which until 2010 included
Pillay, Manormoney   +41 more
core   +2 more sources

Systematic functional identification of cancer multi-drug resistance genes

open access: yesGenome Biology, 2020
Background Drug resistance is a major obstacle in cancer therapy. To elucidate the genetic factors that regulate sensitivity to anti-cancer drugs, we performed CRISPR-Cas9 knockout screens for resistance to a spectrum of drugs.
Man-Tat Lau   +14 more
doaj   +1 more source

Investigation of antibiotic resistance genotypic and phenotypic characteristics of marine aquaculture fish carried in the Dalian area of China

open access: yesFrontiers in Microbiology, 2023
Due to the long-term and irrational use of antibiotics for the prevention and control of bacterial diseases in aquaculture, antibiotic resistance genes have become a new source of pollution in aquatic products.
Zihui Gao   +6 more
doaj   +1 more source

Drug resistance-conferring mutations in Mycobacterium tuberculosis from Madang, Papua New Guinea [PDF]

open access: yes, 2012
: BACKGROUND: Monitoring drug resistance in Mycobacterium tuberculosis is essential to curb the spread of tuberculosis (TB). Unfortunately, drug susceptibility testing is currently not available in Papua New Guinea (PNG) and that impairs TB control in ...
Gagneux, S.   +35 more
core   +1 more source

Chaperonin GroEL/GroES over-expression promotes multi-drug resistance in E. coli following exposure to aminoglycoside antibiotics

open access: yesFrontiers in Microbiology, 2016
Antibiotic resistance is an increasing challenge to modern healthcare. Aminoglycoside antiobiotics cause translation corruption and protein misfolding and aggregation in Escherichia coli.
Lise eGoltermann   +2 more
doaj   +1 more source

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