Results 41 to 50 of about 79,223 (384)
Journal of Infection and Public Health, 2023 Background: Lymphocytic choriomeningitis virus (LCMV) infects many individuals worldwide and causes severe infection in the immunosuppressant recipient, spontaneous abortion, and congenital disabilities in infants.
Muhammad Waqas +9 more
doaj +1 more source
Structural and biophysical analysis of important biomedical enzymes and nano-architectures [PDF]
, 2008 Dopa decarboxylase (DDC) is an important enzyme in the catecholamine biosynthesis pathways. Catecholamines, e.g., dopamine, serotonin, etc. often are the major neuromodulators or neurotransmitters.
Chattopadhyay, Arundhati
core +1 more source
PLoS ONE, 2023 Chikungunya virus (CHIKV) is an emerging viral infectious agent with the potential of causing pandemic. There is neither a protective vaccine nor an approved drug against the virus.
Shirin Mahmoodi +2 more
semanticscholar +1 more source
Vaccines, 2023 Candida dubliniensis is an opportunistic pathogen associated with oral and invasive fungal infections in immune-compromised individuals. Furthermore, the emergence of C. dubliniensis antifungal drug resistance could exacerbate its treatment.
N. Akhtar +8 more
semanticscholar +1 more source
Multi-epitope peptide vaccines for human lymphatic filariasis [PDF]
International Journal of Infectious Diseases, 2014 The rise of drug-resistant tuberculosis threatens the very fabric of traditional tuberculosis control efforts, particularly in South Africa, Eastern Europe and parts of Asia. Initial complacency was guided by laboratory observations which suggested that drug-resistant strains of Mycobacterium tuberculosis are less transmissible than drug-susceptible ...
J. Madhumathi +5 more
openaire +2 more sources
Immunoinformatics study of CD40 ligand-targeting vaccine constructs: a novel immunotherapeutic approach [PDF]
Osong Public Health and Research PerspectivesObjectives Incorporating CD40 ligand (CD40L) into vaccine strategies has shown considerable potential for enhancing immune responses. In this study, we designed and formulated a CD40L-based multi-epitope vaccine construct using immunoinformatics ...
Seyed Amir Sadeghi +4 more
doaj +1 more source
Predicting the effectiveness of hepatitis C virus neutralizing antibodies by bioinformatic analysis of conserved epitope residues using public sequence data [PDF]
, 2018 Hepatitis C virus (HCV) is a global health issue. Although direct-acting antivirals are available to target HCV, there is currently no vaccine. The diversity of the virus is a major obstacle to HCV vaccine development. One approach toward a vaccine is to
Cowton, Vanessa M. +3 more
core +2 more sources
Evidence for conservation in antigen gene sequences combined with extensive polymorphism at VNTR loci [PDF]
, 2020 Theileria parva is a tick‐transmitted apicomplexan protozoan parasite that infects lymphocytes of cattle and African Cape buffalo (Syncerus caffer), causing a frequently fatal disease of cattle in eastern, central and southern Africa.
Ahmed, Jabbar +13 more
core +1 more source
Design of a multi-epitope vaccine candidate against Vibrio cholerae. [PDF]
Sci RepCholera is an acute, highly contagious diarrheal disease caused by the gram-negative bacterium Vibrio cholerae, typically contracted through contaminated water or food. Without timely treatment, cholera can lead to severe dehydration and death. The COVID-19 pandemic has underscored the critical importance of vaccine development, emphasizing the need ...
Koupaei FN +6 more
europepmc +4 more sources
In silico based multi-epitope vaccine design against norovirus
Journal of Biomolecular Structure and Dynamics, 2022 Norovirus (NoV) belongs to the Calciviridae family that causes diarrhoea, vomiting, and stomach pain in people who have acute gastroenteritis (AGE). Identifying multi-epitope dependent vaccines for single stranded positive sense viruses such as NoV has been a long due.
Pallavi M. Shanthappa +4 more
openaire +2 more sources