Results 81 to 90 of about 12,444,642 (294)
Beyond the Unitary State: Multi-Level Governance, Politics, and Cross-Cultural Perspectives on Animal Welfare. [PDF]
Chaney P, Jones IR, Narayan N.
europepmc +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Multi-level Governance and Security: The Security Sector Reform Process in the Central African Republic [PDF]
Analysing how the SSR process in CAR has been defined and then implemented, this article puts emphasis on the international interactions between institutional actors who may be geographically/territorially situated at different levels of the policy ...
Niagalé Bagayoko-Penone
core
European social dialogue as multi-level governance : towards more autonomy and new dependencies [PDF]
Almost twenty years ago the Maastricht Treaty introduced procedures for European Social Dialogue, as part of a larger package of measures to strengthen the social dimension of European integration.
Keune, M.; id_orcid +4 more
core +2 more sources
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
SOME ASPECTS REGARDING REGIONALIZATION IN THE EUROPEAN UNION [PDF]
Regional development policies initiated in the last decades, European countries, aimed at recovery economic and social development locally, economic recovery less developed areas, reducing disparities between the levels of development of the regions.
Ion, POPESCU, Cosmin-Ionut, ENESCU
doaj
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Multi-level Governance: The General Model and the Italian Experience [PDF]
During the last twenty years, the introduction of the principle of subsidiarity and the identification of regions as political entities for the coordination of structural expenditure at the local level have led to the adoption of the principle of multi ...
Zampino, Simona, Bagarani, Massimo
core
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Political Disagreement and Delegation in a Multi-Level Governance Setting [PDF]
A large share of delegation models takes into account the effect of political disagreement when explaining delegation. Yet, delegation models make sharply contrasting predictions on how political disagreement translates into the level of discretion ...
Diane Payne +2 more
core

