Results 81 to 90 of about 159,405 (302)

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Unraveling the Central State, But How? Types of Multi-Level Governance. IHS Political Science Series: 2003, No. 87

open access: yes, 2003
The reallocation of authority upwards, downwards, and sideways from central states has drawn attention from a growing number of scholars in political science.
Marks, Gary, Hooghe, Liesbet
core  

The Economy Governing During Globalization Era [PDF]

open access: yesTheoretical and Applied Economics, 2006
World and national economie governing is an essential premise of the political stability and democratic evolution. In this study are approached theoretical and practical aspects of the economie governing.
Ion Bucur
doaj   +1 more source

SOME ASPECTS REGARDING REGIONALIZATION IN THE EUROPEAN UNION [PDF]

open access: yesStrategii Manageriale, 2014
Regional development policies initiated in the last decades, European countries, aimed at recovery economic and social development locally, economic recovery less developed areas, reducing disparities between the levels of development of the regions.
Ion, POPESCU, Cosmin-Ionut, ENESCU
doaj  

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Multi-level Governance: The General Model and the Italian Experience [PDF]

open access: yes
During the last twenty years, the introduction of the principle of subsidiarity and the identification of regions as political entities for the coordination of structural expenditure at the local level have led to the adoption of the principle of multi ...
Zampino, Simona, Bagarani, Massimo
core  

Unpacking multi-level governance of antimicrobial resistance policies: the case of Guangdong, China. [PDF]

open access: yesHealth Policy Plan, 2022
Chan OSK   +8 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Political Disagreement and Delegation in a Multi-Level Governance Setting [PDF]

open access: yes
A large share of delegation models takes into account the effect of political disagreement when explaining delegation. Yet, delegation models make sharply contrasting predictions on how political disagreement translates into the level of discretion ...
Diane Payne   +2 more
core  

Self-Governance for Sustainable Global Supply Chains: Can it deliver the impacts needed?

open access: yes, 2013
The world community convened in Rio de Janeiro in June 2012 for the third UN Conference on Sustainable Development. We are, however, increasingly facing major persistent threats, which despite being known for a few decades are still far from being ...
Walter J.V. Vermeulen   +3 more
core   +1 more source

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