Results 41 to 50 of about 79,155 (276)
Toward a Standardized Strategy of Clinical Metabolomics for the Advancement of Precision Medicine [PDF]
, 2020 Despite the tremendous success, pitfalls have been observed in every step of a clinical metabolomics workflow, which impedes the internal validity of the study.
Kang, Yun Pyo +6 more
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Towards an integrative multi-omics workflow [PDF]
, 2021 AbstractThe advent of high-throughput techniques has greatly enhanced biological discovery. Last years, analysis of multi-omics data has taken the front seat to improve physiological understanding. Handling functional enrichment results from various biological data raises practical questions.We propose an integrative workflow to better interpret ...
Florian Jeanneret, Stéphane Gazut
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Computational and Structural Biotechnology Journal, 2021 While cost-effective high-throughput technologies provide an increasing amount of data, the analyses of single layers of data seldom provide causal relations.
Otília Menyhárt, Balázs Győrffy
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Journal of Pharmaceutical Analysis, 2023 Bioinformatic analysis of large and complex omics datasets has become increasingly useful in modern day biology by providing a great depth of information, with its application to neuroscience termed neuroinformatics.
Lance M. O'Connor +4 more
doaj +1 more source
Pathway relevance ranking for tumor samples through network-based data integration [PDF]
, 2015 The study of cancer, a highly heterogeneous disease with different causes and clinical outcomes, requires a multi-angle approach and the collection of large multi-omics datasets that, ideally, should be analyzed simultaneously.
Demeester, Piet +5 more
core +3 more sources
A guide to multi-omics data collection and integration for translational medicine
Computational and Structural Biotechnology Journal, 2023 The emerging high-throughput technologies have led to the shift in the design of translational medicine projects towards collecting multi-omics patient samples and, consequently, their integrated analysis.
Efi Athieniti, George M. Spyrou
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Mapping the Human Exposome to Uncover the Causes of Breast Cancer. [PDF]
, 2019 Breast cancer is an important cause of morbidity and mortality for women, yet a significant proportion of variation in individual risk is unexplained. It is reasonable to infer that unexplained breast cancer risks are caused by a myriad of exposures and ...
Bessonneau, Vincent, Rudel, Ruthann A
core +2 more sources
, 2018 New technologies have enabled the investigation of biology and human health at an unprecedented scale and in multiple dimensions. These dimensions include a myriad of properties describing genome, epigenome, transcriptome, microbiome, phenotype, and ...
Goldenberg, Anna +5 more
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Heterogeneity in pure microbial systems: experimental measurements and modeling [PDF]
, 2017 Cellular heterogeneity influences bioprocess performance in ways that until date are not completely elucidated. In order to account for this phenomenon in the design and operation of bioprocesses, reliable analytical and mathematical descriptions are ...
González-Cabaleiro, Rebeca +4 more
core +2 more sources
Computational approaches for network-based integrative multi-omics analysis
Frontiers in Molecular Biosciences, 2022 Advances in omics technologies allow for holistic studies into biological systems. These studies rely on integrative data analysis techniques to obtain a comprehensive view of the dynamics of cellular processes, and molecular mechanisms.
Francis E. Agamah +12 more
doaj +1 more source