Results 91 to 100 of about 10,180,203 (304)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Multi-scale modeling of dense gas-particle flows
, 2012 Dense gas-particle flows are encountered in a variety of industrially important processes for large scale production of fuels, fertilizers and base chemicals.
Kuipers, J.A.M.; id_orcid +2 more
core
, 2009 This paper is a continuation of the paper titled “Concurrent multi-scale modeling of civil infrastructure for analyses on structural deteriorating—Part I: Modeling methodology and strategy” with the emphasis on model updating and verification for the ...
Yu, Y. +7 more
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Multi-Scale Modeling of Physical Properties of Nanoporous Frameworks: Predicting Mechanical, Thermal and Adsorption Behavior [PDF]
Nanoporous frameworks are a large and diverse family of materials, with a key role in various industrial processes and applications such as energy production and conversion, fluid separation, gas storage, water harvesting, and many more.
Arthur, Hardiagon +1 more
core +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Multi-scale modeling - WRF-CIM coupling
, 2018 In this dataset you can find WRF and CIM simulated data produced and used in the paper (Multi-scale modeling of the urban meteorology: Integration of a new canopy model in the WRF model). More details on the datasets can be found in the Python Notebook.
Mauree, Dasaraden (5086469) +1 more
core +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Concurrent multi-scale modeling of structures and damage analyses
, 2007 The methodology and strategy for concurrent multi-scale modeling of large structures such as long span bridges were studied in order to perform the multi-scale numerical analysis on structural, dynamic response and local damage.
Li, Z.X. +4 more
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