Results 51 to 60 of about 276,305 (263)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

MULTI-SCALE MODELLING OF FIBRE BUNDLES

, 2013
The research deals with modelling of fibre assemblies with a view to increase the computational efficiency without restricting the fibre count to predict the intra-yarn fibre interactions.
Chakladar, N. D., Mandal, P.; id_orcid 0000-0002-4051-110X, Potluri, P.; id_orcid 0000-0002-2306-1661   +2 more
openaire   +4 more sources

Studying the Effects of Dissolved Noble Gases and High Hydrostatic Pressure on the Spherical DOPC Bilayer Using Molecular Dynamic Simulations

Membranes
Fine-grained molecular dynamics simulations have been conducted to depict lipid objects enclosed in water and interacting with a series of noble gases dissolved in the medium. The simple point-charge (SPC) water system, featuring a boundary composed of 1,
Eugeny Pavlyuk, Irena Yungerman, Alice Bliznyuk, Yevgeny Moskovitz   +3 more
doaj   +1 more source

Artificial Neural Network-Based Prediction of Total Eccentricities in Existing Buildings Using Ambient Vibration Records [PDF]

Journal of Soft Computing in Civil Engineering
This paper introduces a neural network-based methodology for determining the total floor eccentricity along one axis in existing buildings. The method utilizes ambient vibration-measured natural frequencies and corresponding frequency response amplitudes
Farah Kahlouche, Nouredine Bourahla, Ismail Derbal, Ahmed Mebarki   +3 more
doaj   +1 more source

Knowledge Representation for Multi-Scale Physiology Route Modeling

Frontiers in Neuroinformatics, 2021
We present a framework for the topological and semantic assembly of multiscale physiology route maps. The framework, called ApiNATOMY, consists of a knowledge representation (KR) model and a set of knowledge management (KM) tools.
Natallia Kokash, Bernard de Bono
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Multi-scale computational modelling in biology and physiology

Progress in Biophysics and Molecular Biology, 2008
Recent advances in biotechnology and the availability of ever more powerful computers have led to the formulation of increasingly complex models at all levels of biology. One of the main aims of systems biology is to couple these together to produce integrated models across multiple spatial scales and physical processes.
Southern, J, Pitt−Francis, J, Whiteley, J, Stokeley, D, Kobashi, H, Nobes, R, Kadooka, Y, Gavaghan, D   +7 more
openaire   +6 more sources

Multi-Scale Modelling of Sintering [PDF]

Key Engineering Materials, 2008
Sintering models at the atomistic, particle and component scales are briefly reviewed and problems in the current generation of sintering models are highlighted. A strategy of multi-scale modelling is proposed and our progress in the multiscale modelling is reported.
Jing Zhe Pan, Ruo Yu Huang
openaire   +1 more source

Wavy Ice Patterns as a Result of Morphological Instability of an Ice–Water Interface with Allowance for the Convective–Conductive Heat Transfer Mechanism

Crystals
In this research, the wavy ice patterns that form due to the evolution of morphological perturbations on the water–ice phase transition interface in the presence of a fluid flow are studied. The mathematical model of heat transport from a relatively warm
Dmitri V. Alexandrov, Eugenya V. Makoveeva, Alina D. Pashko   +2 more
doaj   +1 more source